The effect of prostaglandin E1 on the increase of serum lactate and plasma granulocyte elastase activity during radical surgery for esophageal cancer

1994 ◽  
Vol 8 (3) ◽  
Author(s):  
Takae Kawamura ◽  
Kazutoshi Okada ◽  
Hiroshi Okada ◽  
Junne Akiyama ◽  
Midori Ishida ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Prostaglandin E1 ◽  
Radical Surgery ◽  
Serum Lactate ◽  
Elastase Activity ◽  
Granulocyte Elastase

The effect of prostaglandin E1 on the increase of serum lactate and plasma granulocyte elastase activity during radical surgery for esophageal cancer

1994 ◽  
Vol 8 (3) ◽  
pp. 261-264
Author(s):  
Takae Kawamura ◽  
Kazutoshi Okada ◽  
Hiroshi Okada ◽  
Junne Akiyama ◽  
Midori Ishida ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Prostaglandin E1 ◽  
Radical Surgery ◽  
Serum Lactate ◽  
Elastase Activity ◽  
Granulocyte Elastase

scholarly journals A Case of Chylothorax after Radical Surgery for Esophageal Cancer Cured by Lipiodol Lymphangiography

2005 ◽  
Vol 38 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Mamoru Uemura ◽  
Yuichiro Doki ◽  
Osamu Ishikawa ◽  
Jun Ueda ◽  
Kouichi Yoshikawa ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Radical Surgery

VS01.05: RADICAL OPERATION OF ESOPHAGEAL CANCER UNDER 2D THORACOSCOPE

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 44-45
Author(s):  
Jie Jiang ◽  
Xiuyi Yu ◽  
Guojun Geng ◽  
Hongming Liu
Keyword(s):  
Esophageal Cancer ◽  
Conflicts Of Interest ◽  
Radical Surgery ◽  
Basic Operation ◽  
Radical Operation ◽  
Operation Procedure

Abstract Description To The basic operation procedure of esophageal cancer radical surgery. Disclosure All authors have declared no conflicts of interest.

scholarly journals Targeting the Microenvironment in Esophageal Cancer

2021 ◽  
Vol 9 ◽  
Author(s):  
Lei Wang ◽  
Huiqiong Han ◽  
Zehua Wang ◽  
Litong Shi ◽  
Mei Yang ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Survival Rate ◽  
Adverse Reactions ◽  
Radical Surgery ◽  
Treatment Options ◽  
Antiangiogenic Therapy ◽  
Common Type ◽  
New Drugs ◽  
Limited Efficacy ◽  
Important Therapeutic Target

Esophageal cancer (EC) is the eighth most common type of cancer and the sixth leading cause of cancer-related deaths worldwide. At present, the clinical treatment for EC is based mainly on radical surgery, chemotherapy, and radiotherapy. However, due to the limited efficacy of conventional treatments and the serious adverse reactions, the outcome is still unsatisfactory (the 5-year survival rate for patients is less than 25%). Thus, it is extremely important and urgent to identify new therapeutic targets. The concept of tumor microenvironment (TME) has attracted increased attention since it was proposed. Recent studies have shown that TME is an important therapeutic target for EC. Microenvironment-targeting therapies such as immunotherapy and antiangiogenic therapy have played an indispensable role in prolonging survival and improving the prognosis of patients with EC. In addition, many new drugs and therapies that have been developed to target microenvironment may become treatment options in the future. We summarize the microenvironment of EC and the latest advances in microenvironment-targeting therapies in this review.

PS02.125: NEOADJUVANT CHEMOTHERAPY PLUS SURGERY FOR NON-T4 CSTAGE II/III ESOPHAGEAL CANCER: A SINGLE INSTITUTION EXPERIENCE IN JAPAN

2018 ◽  
Vol 31 (Supplement_1) ◽  
pp. 156-157
Author(s):  
Masahiko Ikebe ◽  
Mitsuhiko Ohta ◽  
Masahiko Sugiyama ◽  
Masaru Morita ◽  
Yasushi Toh
Keyword(s):  
Esophageal Cancer ◽  
Postoperative Complications ◽  
Neoadjuvant Chemotherapy ◽  
Adverse Events ◽  
Standard Treatment ◽  
Conflicts Of Interest ◽  
Radical Surgery ◽  
Hospital Death ◽  
Number Of Patients ◽  
Grade 3

Abstract Background In Japan, following the results of JCOG 9907 trial, neoadjuvant chemotherapy (NAC) and radical surgery has been a standard treatment for Non-T4 cStage II/III esophageal cancer. Since 2009 we have also positioned NAC as standard treatment. We examined treatment outcomes and problems in our institute. Methods From 2009 to 2015, there were 64 patients with non-T4 stage II/III esophageal cancer treated with chemotherapy who are planned to undergo curative surgery. The standard NAC regimen consists of 2 courses of CDDP/5-FU (CF) therapy. As standard surgical procedure, subtotal esophagectomy, cervical anastomosis, three regional lymph node dissection were performed. Results The number of patients was 23/41 cases of cStage II/III respectively. 53 patients (88%) completed two courses of NAC. At the end of first course, NAC was terminated due to adverse events in 4 cases and due to the increasing tendency of tumors in 7 cases. NAC-induced adverse events of grade 3 or higher consists of myelosuppression in 27 cases (42%), appetite loss in 5 cases and so on. Surgery was performed in 61 cases (95%), of which R0 operation in 56 cases (88%), R1 operation in 3 cases and R2 operation in 2 cases. Three patients did not undergo surgery due to progressive disease. There were 7 cases (11%) of postoperative complications of Grade 3 or higher, but there was no in-hospital death. In the histological therapeutic effect, there were 5/41/7/4/3 cases for Grade 0/1a/1b/2/3, respectively. Three-year and five-year overall survival rate of all 64 patients were 68% and 47%. In 56 patients who underwent R0 surgery, they were 76% and 61% respectively. Conclusion From the viewpoint of adverse events and postoperative complications, NAC plus radical surgery for cStage II/III esophageal cancer could be performed safely. Considering that more than 60% of the patients belong to cStage III, this treatment strategy resulted in relatively favorable prognosis. Disclosure All authors have declared no conflicts of interest.

scholarly journals Comparative analysis of safety and effect of minimally invasive esophageal cancer radical resection and conventional thoracotomy for esophageal cancer

2018 ◽  
Vol 2 (6) ◽  
Author(s):  
Ke Du ◽  
Zhenxing Wang
Keyword(s):  
Esophageal Cancer ◽  
Blood Loss ◽  
Minimally Invasive ◽  
Lymph Nodes ◽  
Radical Surgery ◽  
Radical Resection ◽  
Control Group ◽  
Clinical Effects ◽  
Intraoperative Blood Loss ◽  
Experimental Group

【Abstract】Objective: To compare the clinical effects of minimally invasive esophageal cancer radical resection and traditional esophageal cancer radical resection.Methods: 200 cases of esophageal cancer radical resection were performed from July 2014 to July 2017 in our hospital.The cases were divided into experimental group and control group, 82 cases in the experimental group and 118 cases in the control group.The experimental group was treated with minimally invasive esophageal cancer radical surgery, and the control group was treated with conventional thoracotomy.Record the comparison between the two groups (1) surgical conditions, including the time of surgery, intraoperative blood loss, hospitalization time; (2) the number of lymph nodes cleaned; (3) the postoperative control group used conventional thoracotomy, including lung lesions, anastomotic fistula / narrow.RESULTS: The parameters of operation time, intraoperative blood loss, hospitalization time, and number of lymph nodes cleaned in the experimental group were lower than those in the control group, and the difference was statistically significant (p<0.05). In addition to pulmonary infection (p<0.05), There was no significant difference in the incidence of other complications between the experimental group and the control group (p>0.05).Conclusion: Minimally invasive esophageal cancer radical resection and conventional thoracotomy have good clinical effects in the treatment of esophageal cancer. Minimally invasive esophageal cancer radical surgery can effectively reduce intraoperative trauma and postoperative reaction, which is worthy of popularization and application.

scholarly journals Diagnosis and Treatment Strategy of Post Operative Chylothorax After Radical Surgery for Esophageal Cancer

2014 ◽  
Vol 39 (4) ◽  
pp. 627-633
Author(s):  
Yoshiyuki Hoya ◽  
Mitsuo Yabe ◽  
Atsushi Watanabe ◽  
Tsuyoshi Hirabayashi ◽  
Shuji Sato ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Treatment Strategy ◽  
Radical Surgery ◽  
Diagnosis And Treatment

scholarly journals Surgical treatment of patient with combination of amiodaron-induced thyrotoxic and esophagesl cancer

2021 ◽  
Vol 14 (4) ◽  
pp. 26-29
Author(s):  
Alexander S. Kuzmichev ◽  
Konstantin V. Pavelets ◽  
Alexey L. Akinchev ◽  
Mikhail A. Protchenkov ◽  
Vasiliy I. Lomakin ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Surgical Treatment ◽  
Malignant Tumor ◽  
Radical Surgery

The article presents the successful experience of surgical treatment of a patient with a malignant tumor of the esophagus, which was detected in a patient with amiodarone-induced thyrotoxicosis. Thyroidectomy made it possible to quickly eliminate thyrotoxicosis and timely perform radical surgery for esophageal cancer.

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