Oral metronidazole does not improve cyclosporine A-induced gingival hyperplasia

1997 ◽  
Vol 11 (5) ◽  
pp. 552-555 ◽  
Author(s):  
Christoph Aufricht ◽  
Eva L. Hogan ◽  
Robert B. Ettenger
Keyword(s):  
Cyclosporine A ◽  
Gingival Hyperplasia ◽  
Oral Metronidazole

Nifedipine aggravates cyclosporine A-induced gingival hyperplasia

1994 ◽  
Vol 8 (2) ◽  
pp. 181-185 ◽  
Author(s):  
Arend B�kenkamp ◽  
Bettina Bohnhorst ◽  
Christian Beier ◽  
Norbert Albers ◽  
Gisela Offner ◽  
...  
Keyword(s):  
Cyclosporine A ◽  
Gingival Hyperplasia

Cyclosporine A-Induced Gingival Hyperplasia Pemphigus Vulgaris: Literature Review and Report of a Case

2000 ◽  
Vol 71 (4) ◽  
pp. 650-656 ◽  
Author(s):  
Orit Oettinger-Barak ◽  
Eli E. Machtei ◽  
Micha Peled ◽  
Shlomi Barak ◽  
Imad Abu L-Naaj ◽  
...  
Keyword(s):  
Literature Review ◽  
Cyclosporine A ◽  
Pemphigus Vulgaris ◽  
Gingival Hyperplasia

Gingival hyperplasia in beagle dog treated with Cyclosporine A

2012 ◽  
Vol 211 ◽  
pp. S190
Author(s):  
Paolo Angelo Colombo ◽  
Elena Riccardi ◽  
Guido Di Gallo ◽  
Francesco Marchesi ◽  
Anna Maria Giusti
Keyword(s):  
Cyclosporine A ◽  
Gingival Hyperplasia ◽  
Beagle Dog

Analysis of Peripheral Blood Leukocytes in Patients With Cyclosporine A-Induced Gingival Hyperplasia

1998 ◽  
Vol 69 (12) ◽  
pp. 1435-1439 ◽  
Author(s):  
Írfan Cebeci ◽  
Alpdoǧan Kantarci ◽  
Nuray Gürel ◽  
Suzan Adin ◽  
Özen Tuncer ◽  
...  
Keyword(s):  
Cyclosporine A ◽  
Peripheral Blood ◽  
Gingival Hyperplasia ◽  
Peripheral Blood Leukocytes ◽  
Blood Leukocytes

Treatment of gingival hyperplasia induced by cyclosporine A

2008 ◽  
Vol 2 (3) ◽  
pp. 290-294
Author(s):  
Jingzhi Ma ◽  
Ming Li ◽  
Yingguang Cao
Keyword(s):  
Cyclosporine A ◽  
Gingival Hyperplasia

Ultrastructural Features of Cyclosporine A-Induced Gingival Hyperplasia

1993 ◽  
Vol 64 (11) ◽  
pp. 1092-1097 ◽  
Author(s):  
Giustiniano Mariani ◽  
Carla Calastrini ◽  
Francesco Carinci ◽  
Riccardo Marzola ◽  
Giorgio Calura
Keyword(s):  
Cyclosporine A ◽  
Gingival Hyperplasia

scholarly journals Long-term maintenance therapy with Cyclosporine A in adults with generalized pustular psoriasis

2019 ◽  
Vol 9 (5) ◽  
pp. 19-21 ◽  
Author(s):  
Kamel El-Reshaid ◽  
Al-Bader Shaima
Keyword(s):  
Cyclosporine A ◽  
Light Exposure ◽  
Skin Lesions ◽  
Pustular Psoriasis ◽  
Gingival Hyperplasia ◽  
Immune Mediated ◽  
Generalized Pustular Psoriasis ◽  
Liver And Kidney

Generalized pustular psoriasis (GPP) is a rare and serious immune-mediated skin disorder that is characterized by a widespread eruption of sterile and subcorneal pustules.  In the present study we investigated the efficacy of Cyclosporine A (Cy A) in treatment of 9 adults with drug-refractory GPP viz. topical Corticosteroids, retinoids, methotrexate and narrow-band ultraviolet light exposure (UVB).  Initially; they were resuscitated as burn patients. Cy A was administered on day 1 at a dose of 100 mg twice daily either in the form of syrup or Neoral capsules.  In most patients, skin lesions had healed by 6 weeks and the dose of Cy A was reduced to minimum to prevent further recurrence.  Seven patients had required 50 mg twice daily and 2 were controlled with 50 mg am and 25 mg pm.  On follow up, there was no serious relapse, liver and kidney disease.  Minor complications included; hirsutism and dark skin (n: 5) and gingival hyperplasia (n: 2). Trial to replace Cy A with Tacrolimus (Prograf) failed to maintain remission.  In conclusion; Cy A is a safe and effective treatment for GPP. Keywords: Cyclosporin A, treatment, psoriasis, pustular.

Comparison of CO2 laser gingivectomy and conventional gingivectomy used for treatment of cyclosporine A-induced gingival hyperplasia – case report

2012 ◽  
Vol 66 (1) ◽  
pp. 130-136
Author(s):  
Elżbieta Dembowska ◽  
Agnieszka Droździk ◽  
Magdalena Malczyńska-Kocińska
Keyword(s):  
Case Report ◽  
Co2 Laser ◽  
Cyclosporine A ◽  
Gingival Hyperplasia

scholarly journals Cosmetically disfiguring side effects of cyclosporine A in an adolescent population

2021 ◽  
Vol 9 (1) ◽  
pp. 12-14
Author(s):  
Shamali Abeyagunawardena ◽  
ESK DeSilva ◽  
Asiri S Abeyagunawardena
Keyword(s):  
Side Effects ◽  
Cyclosporine A ◽  
Clinical Status ◽  
Tertiary Care ◽  
Immunosuppressive Agent ◽  
Gingival Hyperplasia ◽  
Care Hospital ◽  
Cutaneous Manifestations ◽  
Cutaneous Side Effects ◽  
Asian Populations

Cyclosporine A (CsA) is a potent immunosuppressive agent commonly used in nephrotic syndrome and in organ transplanted patients. However, its applications are limited, due to undesirable adverse effects. The cutaneous manifestations of the drug are well documented in the western countries and some studies indicate a higher incidence among Asian populations. However, there is paucity of data about its cutaneous side effects on Asian patients thus making it difficult to counsel patients and parents before its use. We recruited children and adolescents between 12 and 20 years attending the nephrology clinic at a tertiary care hospital in Sri Lanka who have been receiving CsA more than a year. Patients who received other medication which may aggravate gingival hyperplasia, acne or hypertrichosis were excluded from the study. The dermatological manifestations of the selected children were assessed and recorded by experienced clinicians. Our study consisted of 64 patients who satisfied the inclusion criteria. There were 41 male and 23 females with a median age of 16.6 years. All of them received CsA at a dose between 5-10 mg/kg/day at induction, which was tapered towards a dose of 3 mg/kg/day, based on clinical status as well as serum level of the drug. Among the clinical features observed, hypertrichosis was seen in 32 males (78%) and in all 23 female patients (100%); Gum hypertrophy was seen in 34 patients (53%) and acne was noted only in 8 patients. The commonest cutaneous side effect was hypertrichosis, significantly seen among female subjects, which is a serious point of distress to patients and their families. Gum hypertrophy was also observed among a significant number but could be reduced by regular dental care. These findings will be remarkably useful when counselling before commencing on CsA therapy in adolescent patients.

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