Carbon dioxide pneumoperitoneum reduces levels of TNF-a mRNA in the brain, liver, and peritoneum in mice

2001 ◽  
Vol 15 (6) ◽  
pp. 609-613 ◽  
Author(s):  
H. Kamei ◽  
S. Yoshida ◽  
K. Yamasaki ◽  
T. Tajiri ◽  
K. Shirouzu
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Pneumoperitoneum ◽  
The Brain

964: Direct Visualization of Renal Hemodyanamics Affected by Carbon Dioxide Pneumoperitoneum

2007 ◽  
Vol 177 (4S) ◽  
pp. 319-319
Author(s):  
Naoto Sassa ◽  
Ryohei Hattori ◽  
Yoshinari Ono ◽  
Tokunori Yamamoto ◽  
Momokazu Gotoh
Keyword(s):  
Carbon Dioxide ◽  
Direct Visualization ◽  
Carbon Dioxide Pneumoperitoneum

Hypercarbia during carbon dioxide pneumoperitoneum

1992 ◽  
Vol 163 (1) ◽  
pp. 186-190 ◽  
Author(s):  
Stephen D. Fitzgerald ◽  
Charles H. Andrus ◽  
Lawrence J. Baudendistel ◽  
Thomas E. Dahms ◽  
Donald L. Kaminski
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Pneumoperitoneum

Effects of Carbon Dioxide and Oxygen on Properties of Experimental Seizures in Mice

1955 ◽  
Vol 184 (1) ◽  
pp. 202-208 ◽  
Author(s):  
Dixon M. Woodbury ◽  
Lawrence T. Rollins ◽  
Joyce R. Henrie ◽  
Joseph C. Jones ◽  
Tada Sato
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Concentration ◽  
Anticonvulsant Effect ◽  
Maximal Electroshock ◽  
Low Oxygen ◽  
Excitatory Effect ◽  
The Brain ◽  
Electroshock Seizures ◽  
Tonic Phase ◽  
Convulsant Dose

The influence of various concentrations of carbon dioxide and oxygen on the pattern of maximal electroshock seizures (MES), on pentylenetetrazol (Metrazol)-induced seizures, and on recovery time (RT50) from MES has been studied in mice. The major results are summarized as follows: Increasing the concentration of carbon dioxide in 20% oxygen resulted in marked changes in the MES pattern. The duration of the tonic flexor component was increased, and the duration of the tonic extensor component and of the entire tonic phase was decreased; the ratio of flexion to extension was increased markedly. These changes indicate an anticonvulsant effect of carbon dioxide. Carbon dioxide in a concentration of 15.6% protected 50% of mice against a 97% convulsant dose (CD97) of Metrazol. Hypoxia, induced by inhalation of 15 or 10% oxygen, decreased the duration of the tonic flexor component and increased the duration of the tonic extensor component of the MES; the duration of the entire tonic phase was increased; the ratio of flexion to extension was slightly decreased. These changes indicate an excitatory effect of low oxygen concentrations on the brain, under the stated conditions. Hyperoxia, induced by inhalation of 50, 75 or 90% oxygen, in contrast to hypoxia, resulted in effects on MES similar to those produced by inhalation of carbon dioxide. The RT50 was slightly, but not significantly, decreased by hypoxia (15% oxygen), unchanged by hyperoxia (50% oxygen), and markedly increased by an increase in carbon dioxide concentration. Carbon dioxide (5 and 10%) combined with hypoxia (10% oxygen) produced effects on MES pattern and RT50 similar to those produced by carbon dioxide in 20% oxygen.

Electron-Microscopic Alterations of the Peritoneum after Both Cold and Heated Carbon Dioxide Pneumoperitoneum

2005 ◽  
Vol 125 (1) ◽  
pp. 73-77 ◽  
Author(s):  
Mehmet Erikoglu ◽  
Serdar Yol ◽  
Mustafa Cihat Avunduk ◽  
Esra Erdemli ◽  
Alp Can
Keyword(s):  
Carbon Dioxide ◽  
Electron Microscopic ◽  
Carbon Dioxide Pneumoperitoneum

scholarly journals Correction to: Effects of different sufentanil target concentrations on the MACBAR of sevoflurane in patients with carbon dioxide pneumoperitoneum stimulus

2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yanxia Guo ◽  
Dan Wang ◽  
Xiaolin Yang ◽  
Pingping Jiang ◽  
Juan Xu ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Carbon Dioxide Pneumoperitoneum

An amendment to this paper has been published and can be accessed via the original article.

Hypoxic-hypercapnic interaction in subjects with bilateral cerebral dysfunction

1963 ◽  
Vol 18 (6) ◽  
pp. 1139-1145 ◽  
Author(s):  
Fred Plum ◽  
Harold W. Brown
Keyword(s):  
Carbon Dioxide ◽  
Brain Damage ◽  
Pyramidal Tract ◽  
Ventilatory Response ◽  
Cerebral Dysfunction ◽  
Tract Disease ◽  
The Brain ◽  
Carbon Dioxide Response ◽  
Ventilatory Response To Hypoxia ◽  
Respiratory Responses

To analyze cerebral influences modifying autonomic respiratory responses, we compared normals and patients with bilateral pyramidal tract disease for their ventilatory response to hypoxia and hypoxia-hypercapnia. During eucapnia, the two groups showed similar hypoxic responses. During hypercapnia, the ventilatory response to hypoxia was greater in the brain-damaged subjects. This apparent augmentation, however, was due entirely to anoxia interacting with an abnormally facilitated carbon dioxide sensitivity: compared with normals, brain-damaged patients at PaOO2 90–100 mm Hg showed an 85% greater CO2 response, and at PaOO2 50 mm Hg showed a 79% greater CO2 response. Since cerebral dysfunction facilitated the ventilatory response to hypoxia-hypercapnia combined but not the response to hypoxia alone, the results imply that the two respiratory stimuli interact centrally rather than peripherally. respiration; brain damage; interaction; carbon dioxide response; forebrain effects; ventilation with CNS disease Submitted on February 18, 1963

scholarly journals Pneumoperitoneum in Veterinary Laparoscopy: A Review

2020 ◽  
Vol 7 (2) ◽  
pp. 64
Author(s):  
Jacqueline Scott ◽  
Ameet Singh ◽  
Alexander Valverde
Keyword(s):  
Carbon Dioxide ◽  
Sample Population ◽  
Carbon Dioxide Insufflation ◽  
Gasless Laparoscopy ◽  
Carbon Dioxide Pneumoperitoneum ◽  
Working Space ◽  
Co2 Insufflation ◽  
Post Operative Pain ◽  
Electronic Database Search ◽  
Alternative Techniques

Objective: To review the effects of carbon dioxide pneumoperitoneum during laparoscopy, evaluate alternative techniques to establishing a working space and compare this to current recommendations in veterinary surgery. Study Design: Literature review. Sample Population: 92 peer-reviewed articles. Methods: An electronic database search identified human and veterinary literature on the effects of pneumoperitoneum (carbon dioxide insufflation for laparoscopy) and alternatives with a focus on adaptation to the veterinary field. Results: Laparoscopy is the preferred surgical approach for many human and several veterinary procedures due to the lower morbidity associated with minimally invasive surgery, compared to laparotomy. The establishment of a pneumoperitoneum with a gas most commonly facilitates a working space. Carbon dioxide is the preferred gas for insufflation as it is inert, inexpensive, noncombustible, colorless, excreted by the lungs and highly soluble in water. Detrimental side effects such as acidosis, hypercapnia, reduction in cardiac output, decreased pulmonary compliance, hypothermia and post-operative pain have been associated with a pneumoperitoneum established with CO2 insufflation. As such alternatives have been suggested such as helium, nitrous oxide, warmed and humidified carbon dioxide and gasless laparoscopy. None of these alternatives have found a consistent benefit over standard carbon dioxide insufflation. Conclusions: The physiologic alterations seen with CO2 insufflation at the current recommended intra-abdominal pressures are mild and of transient duration. Clinical Significance: The current recommendations in veterinary laparoscopy for a pneumoperitoneum using carbon dioxide appear to be safe and effective.

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