Use of scale-down methods to rapidly apply natural yeast homogenisation models to a recombinant strain

1998 ◽  
Vol 19 (5) ◽  
pp. 373 ◽  
Author(s):  
E. G. Varga ◽  
N. J. Titchener-Hooker ◽  
P. Dunnill
Keyword(s):  
Recombinant Strain ◽  
Scale Down

Impact of Big Data over Telecom Industry

2018 ◽  
Vol 6 (2) ◽  
Author(s):  
Muhammad Waqar Khan ◽  
Muhammad Asghar Khan ◽  
Muhammad Alam ◽  
Wajahat Ali
Keyword(s):  
Big Data ◽  
Data Science ◽  
Cell Phones ◽  
Smart Phones ◽  
World Population ◽  
Huge Amount ◽  
Scale Down ◽  
Telecom Industry ◽  
Telecom Sector ◽  
Theoretical Computing

<p>During past few years, data is growing exponentially attracting researchers to work a popular term, the Big Data. Big Data is observed in various fields, such as information technology, telecommunication, theoretical computing, mathematics, data mining and data warehousing. Data science is frequently referred with Big Data as it uses methods to scale down the Big Data. Currently<br />more than 3.2 billion of the world population is connected to internet out of which 46% are connected via smart phones. Over 5.5 billion people are using cell phones. As technology is rapidly shifting from ordinary cell phones towards smart phones, therefore proportion of using internet is also growing. There<br />is a forecast that by 2020 around 7 billion people at the globe will be using internet out of which 52% will be using their smart phones to connect. In year 2050 that figure will be touching 95% of world population. Every device connect to internet generates data. As majority of the devices are using smart phones to<br />generate this data by using applications such as Instagram, WhatsApp, Apple, Google, Google+, Twitter, Flickr etc., therefore this huge amount of data is becoming a big threat for telecom sector. This paper is giving a comparison of amount of Big Data generated by telecom industry. Based on the collected data<br />we use forecasting tools to predict the amount of Big Data will be generated in future and also identify threats that telecom industry will be facing from that huge amount of Big Data.</p>

scholarly journals Challenge of Naïve and Vaccinated Pigs with a Vaccine-Derived Recombinant Porcine Reproductive and Respiratory Syndrome Virus 1 Strain (Horsens Strain)

Vaccines ◽  
2021 ◽  
Vol 9 (5) ◽  
pp. 417
Author(s):  
Lise K. Kvisgaard ◽  
Lars E. Larsen ◽  
Charlotte S. Kristensen ◽  
Frédéric Paboeuf ◽  
Patricia Renson ◽  
...  
Keyword(s):  
Viral Load ◽  
Experimental Model ◽  
Recombinant Strain ◽  
Clinical Signs ◽  
Growing Pigs ◽  
Respiratory Syndrome Virus ◽  
Almost All ◽  
Highly Virulent

In July 2019, a vaccine-derived recombinant Porcine reproductive and respiratory syndrome virus 1 strain (PRRSV-1) (Horsens strain) infected more than 40 Danish sow herds, resulting in severe losses. In the present study, the pathogenicity of the recombinant Horsens strain was assessed and compared to a reference PRRSV-1 strain using a well-characterized experimental model in young SPF pigs. Furthermore, the efficacies of three different PRRSV-1 MLV vaccines to protect pigs against challenge with the recombinant strain were assessed. Following challenge, the unvaccinated pigs challenged with the Horsens strain had significant increased viral load in serum compared to all other groups. No macroscopic changes were observed at necropsy, but tissue from the lungs and tonsils from almost all pigs were PRRSV-positive. The viral load in serum was lower in all vaccinated groups compared to the unvaccinated group challenged with the Horsens strain, and only small differences were seen among the vaccinated groups. The findings in the present study, combined with two other recent reports, indicate that this recombinant “Horsens” strain indeed is capable of inducing infection in growing pigs as well as in pregnant sows that is comparable to or even exceeding those induced by typical PRRSV-1, subtype 1 strains. However, absence of notable clinical signs and lack of significant macroscopic changes indicate that this strain is less virulent than previously characterized highly virulent PRRSV-1 strains.

scholarly journals Maintaining paediatric cardiac services during the COVID-19 pandemic in a developing country in sub-Saharan Africa: guidelines for a “scale up” in the face of a global “scale down”

2020 ◽  
Vol 30 (11) ◽  
pp. 1588-1594
Author(s):  
Ogochukwu J. Sokunbi ◽  
Ogadinma Mgbajah ◽  
Augustine Olugbemi ◽  
Bassey O. Udom ◽  
Ariyo Idowu ◽  
...  
Keyword(s):  
Scale Up ◽  
Global Scale ◽  
International Travel ◽  
Sub Saharan Africa ◽  
African Continent ◽  
Tertiary Centre ◽  
The Face ◽  
Scale Down ◽  
Sub Saharan ◽  
International Experts

AbstractThe COVID-19 pandemic is currently ravaging the globe and the African continent is not left out. While the direct effects of the pandemic in regard to morbidity and mortality appear to be more significant in the developed world, the indirect harmful effects on already insufficient healthcare infrastructure on the African continent would in the long term be more detrimental to the populace. Women and children form a significant vulnerable population in underserved areas such as the sub-Saharan region, and expectedly will experience the disadvantages of limited healthcare coverage which is a major fall out of the pandemic. Paediatric cardiac services that are already sparse in various sub-Saharan countries are not left out of this downsizing. Restrictions on international travel for patients out of the continent to seek medical care and for international experts into the continent for regular mission programmes leave few options for children with cardiac defects to get the much-needed care.There is a need for a region-adapted guideline to scale-up services to cater for more children with congenital heart disease (CHD) while providing a safe environment for healthcare workers, patients, and their caregivers. This article outlines measures adapted to maintain paediatric cardiac care in a sub-Saharan tertiary centre in Nigeria during the COVID-19 pandemic and will serve as a guide for other institutions in the region who will inadvertently need to provide these services as the demand increases.

Cytologic detection of Toxoplasma gondii in the cerebrospinal fluid of a dog and in vitro isolation of a unique mouse-virulent recombinant strain

2021 ◽  
pp. 104063872199668
Author(s):  
Waléria Borges-Silva ◽  
Mariana M. Rezende-Gondim ◽  
Gideão S. Galvão ◽  
Daniele S. Rocha ◽  
George R. Albuquerque ◽  
...  
Keyword(s):  
Cerebrospinal Fluid ◽  
Toxoplasma Gondii ◽  
Recombinant Strain ◽  
Neospora Caninum ◽  
Clinical Signs ◽  
Species Identity ◽  
Cytologic Examination ◽  
Pcr Rflp ◽  
Tissue Homogenates

Parasites resembling Neospora caninum or Toxoplasma gondii were detected by cytologic examination of cerebrospinal fluid (CSF) from a dog with neurologic disease. The dog became severely ill and was euthanized. Canine tissue homogenates were used for direct parasite isolation in cell culture, bioassay in 2 mouse lineages, and PCR. T. gondii was isolated in monkey kidney cells, and species identity was confirmed by PCR. Inoculated parasites were highly virulent for mice, which developed clinical signs and were euthanized immediately. PCR-RFLP for T. gondii using the cultured isolate (TgDgBA22) was conducted with 12 genetic markers, and a unique recombinant strain was identified. Detection of T. gondii by CSF cytology, although described in humans, had not been reported previously in dogs, to our knowledge, and was crucial for the diagnosis of toxoplasmosis in the examined dog.

scholarly journals The vibro-impact capsule system in millimetre scale: numerical optimisation and experimental verification

Meccanica ◽  
2020 ◽  
Vol 55 (10) ◽  
pp. 1885-1902
Author(s):  
Yang Liu ◽  
Joseph Páez Chávez ◽  
Jiajia Zhang ◽  
Jiyuan Tian ◽  
Bingyong Guo ◽  
...  
Keyword(s):  
Dynamical System ◽  
Mathematical Formulation ◽  
Path Following ◽  
Piecewise Smooth ◽  
Experimental Results ◽  
Scale Down ◽  
Speed Up ◽  
Small Bowel Endoscopy ◽  
Numerical Optimisation ◽  
Smooth Dynamical System

Abstract The vibro-impact capsule system has been studied extensively in the past decade because of its research challenges as a piecewise-smooth dynamical system and broad applications in engineering and healthcare technologies. This paper reports our team’s first attempt to scale down the prototype of the vibro-impact capsule to millimetre size, which is 26 mm in length and 11 mm in diameter, aiming for small-bowel endoscopy. Firstly, an existing mathematical model of the prototype and its mathematical formulation as a piecewise-smooth dynamical system are reviewed in order to carry out numerical optimisation for the prototype by means of path-following techniques. Our numerical analysis shows that the prototype can achieve a high progression speed up to 14.4 mm/s while avoiding the collision between the inner mass and the capsule which could lead to less propulsive force on the capsule so causing less discomfort on the patient. Secondly, the experimental rig and procedure for testing the prototype are introduced, and some preliminary experimental results are presented. Finally, experimental results are compared with the numerical results to validate the optimisation as well as the feasibility of the vibro-impact technique for the potential of a controllable endoscopic procedure.

Scale down of parsley cell cultures to screen putative priming compounds for agro-industry

2016 ◽  
Vol 33 ◽  
pp. S38
Author(s):  
Jana Schilling ◽  
Stefan Mahr ◽  
Britta Schillheim ◽  
Uwe Conrath ◽  
Jochen Büchs
Keyword(s):  
Cell Cultures ◽  
Scale Down

scholarly journals Direct Production of 5-Oxo Derivatives of Avermectins by a Recombinant Strain of Streptomyces avermitilis.

1995 ◽  
Vol 48 (1) ◽  
pp. 95-97 ◽  
Author(s):  
HARUO IKEDA ◽  
YOSHIO TAKADA ◽  
CHANG-HONG PANG ◽  
KEIICHI MATSUZAKI ◽  
HARUO TANAKA ◽  
...  
Keyword(s):  
Recombinant Strain ◽  
Streptomyces Avermitilis ◽  
Direct Production ◽  
Derivatives Of

scholarly journals Scale-down characterization of post-centrifuge flocculation processes for high-throughput process development

2014 ◽  
Vol 111 (12) ◽  
pp. 2486-2498 ◽  
Author(s):  
Georgina Espuny Garcia del Real ◽  
Jim Davies ◽  
Daniel G. Bracewell
Keyword(s):  
High Throughput ◽  
Process Development ◽  
Scale Down
Sign in / Sign up

Export Citation Format

Share Document