The heritability of human longevity: a population-based study of 2872 Danish twin pairs born 1870-1900

1996 ◽  
Vol 97 (3) ◽  
pp. 319-323 ◽  
Author(s):  
A. M. Herskind ◽  
Matthew McGue ◽  
Niels V. Holm ◽  
Thorkild I. A. Sørensen ◽  
Bent Harvald ◽  
...  
1996 ◽  
Vol 97 (3) ◽  
pp. 319-323 ◽  
Author(s):  
Anne Maria Herskind ◽  
Matthew McGue ◽  
Niels V. Holm ◽  
Thorkild I. A. Sørensen ◽  
Bent Harvald ◽  
...  

2001 ◽  
Vol 86 (2) ◽  
pp. 930-934 ◽  
Author(s):  
Thomas Heiberg Brix ◽  
Kirsten Ohm Kyvik ◽  
Kaare Christensen ◽  
Laszlo Hegedüs

2001 ◽  
Vol 44 (2-3) ◽  
pp. 167-178 ◽  
Author(s):  
Marianne Juel Kjeldsen ◽  
Kirsten Ohm Kyvik ◽  
Kaare Christensen ◽  
Mogens Laue Friis

2007 ◽  
Vol 76 (6) ◽  
pp. 369-375 ◽  
Author(s):  
Michael Martini Jørgensen ◽  
Robert Zachariae ◽  
Axel Skytthe ◽  
Kirsten Kyvik

2005 ◽  
Vol 8 (2) ◽  
pp. 138-147 ◽  
Author(s):  
Marianne J. Kjeldsen ◽  
Linda A. Corey ◽  
Marit H. Solaas ◽  
Mogens L. Friis ◽  
Jennifer R. Harris ◽  
...  

AbstractThe purpose of the study was to describe a large sample of twins reporting a history of seizures, to characterize seizures in the three subpopulations, and to estimate the relative importance of genetic and environmental factors in seizure occurrence. Seizure history was determined by questionnaires completed by twins in population-based twin registries in the United States, Norway and Denmark. Concordance rates were calculated for all seizure categories within and across twin populations. Of 47,626 twin pairs evaluated, 6234 reported a history of seizures in one or both twins. Concordance rates were significantly higher for monozygotic (MZ) versus dizygotic (DZ) pairs for all seizure categories within and across populations. The results of this study involving the largest unselected, population-based sample of twins with seizures assembled to date confirm the importance of genetic factors in determining risk for epilepsy, febrile seizures, other seizures and staring spells. This sample is likely to provide an important resource for studying the genetics of epilepsy subtypes and febrile seizures.


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