Cloning of the gene encoding the catalytic subunit of casein kinase II from the yeast Yarrowia lipolytica

1997 ◽  
Vol 256 (4) ◽  
pp. 355-364 ◽  
Author(s):  
P. H. Benetti ◽  
S. I. Kim ◽  
M. Canonge ◽  
T. Chardot ◽  
J. C. Meunier
Keyword(s):  
Yarrowia Lipolytica ◽  
Casein Kinase Ii ◽  
Casein Kinase ◽  
Catalytic Subunit ◽  
Gene Encoding ◽  
Yeast Yarrowia Lipolytica

Functional analysis of Trichoderma reesei CKIIα2, a catalytic subunit of casein kinase II

2015 ◽  
Vol 99 (14) ◽  
pp. 5929-5938 ◽  
Author(s):  
Mingyu Wang ◽  
Hui Yang ◽  
Meiling Zhang ◽  
Kuimei Liu ◽  
Hanbin Wang ◽  
...  
Keyword(s):  
Functional Analysis ◽  
Trichoderma Reesei ◽  
Casein Kinase Ii ◽  
Casein Kinase ◽  
Catalytic Subunit

Insert Regions in Domain X of the Casein Kinase II Catalytic Subunit

1995 ◽  
Vol 229 (3) ◽  
pp. 703-709 ◽  
Author(s):  
Tony Tiganis ◽  
Colin M. House ◽  
Trazel Teh ◽  
Bruce E. Kemp
Keyword(s):  
Casein Kinase Ii ◽  
Casein Kinase ◽  
Catalytic Subunit

scholarly journals Insert Regions in Domain X of the Casein Kinase II Catalytic Subunit

2008 ◽  
Vol 229 (3) ◽  
pp. 703-709
Author(s):  
Tony Tiganis ◽  
Colin M. House ◽  
Trazel Teh ◽  
Bruce E. Kemp
Keyword(s):  
Casein Kinase Ii ◽  
Casein Kinase ◽  
Catalytic Subunit

Isolation, sequencing, and disruption of the CKA1 gene encoding the alpha subunit of yeast casein kinase II

1988 ◽  
Vol 8 (11) ◽  
pp. 4981-4990
Author(s):  
J L Chen-Wu ◽  
R Padmanabha ◽  
C V Glover
Keyword(s):  
Amino Acid ◽  
Amino Acid Sequence ◽  
Gene Product ◽  
Casein Kinase Ii ◽  
Casein Kinase ◽  
Protein Sequencing ◽  
Alpha Subunit ◽  
Yeast Genome ◽  
Gene Encoding ◽  
Alpha Gene

Casein kinase II of Saccharomyces cerevisiae contains two distinct catalytic subunits, alpha and alpha', which must be encoded by separate genes (R. Padmanabha and C. V. C. Glover, J. Biol. Chem. 262:1829-1835, 1987). The gene encoding the 42-kilodalton alpha subunit has been isolated by screening a yeast genomic library with oligonucleotide probes synthesized on the basis of the N-terminal amino acid sequence of the polypeptide. This gene (designated CKA1) contains an intron-free open reading frame of 372 amino acid residues. The deduced amino acid sequence is 67% identical to the alpha subunit of Drosophila melanogaster casein kinase II. The CKA1 gene product appears to be distantly related to other known protein kinases but exhibits highest similarity to the CDC28 gene product and its homolog in other species. Gene replacement techniques have been used to generate a null cka1 mutant allele. Haploid and diploid strains lacking a functional CKA1 gene appear to be phenotypically wild type, presumably because of the presence of the alpha' gene. Interestingly, the CKA1 gene appears to be single copy in the yeast genome; i.e., the alpha' gene, whose existence is known from biochemical studies and protein sequencing, cannot be detected by low-stringency hybridization.

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