Construction and rapid screening of a representative yeast artificial chromosome library from the Plasmodium falciparum strain Dd2

1996 ◽  
Vol 83 (1) ◽  
pp. 87-89 ◽  
Author(s):  
Anamaria A. Camargo ◽  
Katja Fischer ◽  
M. Lanzer
Keyword(s):  
Plasmodium Falciparum ◽  
Yeast Artificial Chromosome ◽  
Artificial Chromosome ◽  
Rapid Screening ◽  
Yeast Artificial Chromosome Library ◽  
Falciparum Strain

Construction of a large-insert yeast artificial chromosome library of the rat genome

1997 ◽  
Vol 8 (4) ◽  
pp. 284-284 ◽  
Author(s):  
M. L. Haldi ◽  
P. Lim ◽  
K. Kaphingst ◽  
U. Akella ◽  
J. Whang ◽  
...  
Keyword(s):  
Yeast Artificial Chromosome ◽  
Artificial Chromosome ◽  
Yeast Artificial Chromosome Library ◽  
Rat Genome

A comprehensive large-insert yeast artificial chromosome library for physical mapping of the mouse genome

1996 ◽  
Vol 7 (10) ◽  
pp. 767-769 ◽  
Author(s):  
M. L. Haldi ◽  
C. Strickland ◽  
P. Lim ◽  
V. VanBerkel ◽  
X. -N. Chen ◽  
...  
Keyword(s):  
Physical Mapping ◽  
Mouse Genome ◽  
Yeast Artificial Chromosome ◽  
Artificial Chromosome ◽  
Yeast Artificial Chromosome Library

scholarly journals Expression of var genes located within polymorphic subtelomeric domains of Plasmodium falciparum chromosomes.

1997 ◽  
Vol 17 (7) ◽  
pp. 3679-3686 ◽  
Author(s):  
K Fischer ◽  
P Horrocks ◽  
M Preuss ◽  
J Wiesner ◽  
S Wünsch ◽  
...  
Keyword(s):  
Plasmodium Falciparum ◽  
Yeast Artificial Chromosome ◽  
Antigenic Variation ◽  
Chromosome Analysis ◽  
Artificial Chromosome ◽  
Chromosome 8 ◽  
Chromosome 2 ◽  
Var Genes ◽  
Var Gene ◽  
Contig Map

Plasmodium falciparum var genes encode a diverse family of proteins, located on the surfaces of infected erythrocytes, which are implicated in the pathology of human malaria through antigenic variation and adhesion of infected erythrocytes to the microvasculature. We have constructed a complete representative telomere-to-telomere yeast artificial chromosome (YAC) contig map of the P. falciparum chromosome 8 for studies on the chromosomal organization, distribution, and expression of var genes. Three var gene loci were identified on chromosome 8, two of which map close to the telomeres at either end of the chromosome. Analysis of the previously described chromosome 2 contig map and random P. falciparum telomeric YAC clones revealed that most, if not all, 14 P. falciparum chromosomes contain var genes in a subtelomeric location. Mapping the chromosomal location of var genes expressed in a long-term culture of the P. falciparum isolate Dd2 revealed that four of the five different expressed var genes identified map within subtelomeric locations. Expression of var genes from a chromosomal domain known for frequent rearrangements has important implications for the mechanism of var gene switching and the generation of novel antigenic and adhesive phenotypes.

scholarly journals Genomic analysis using a yeast artificial chromosome library with mouse DNA inserts.

1992 ◽  
Vol 89 (6) ◽  
pp. 2456-2460 ◽  
Author(s):  
J. M. Rossi ◽  
D. T. Burke ◽  
J. C. Leung ◽  
D. S. Koos ◽  
H. Chen ◽  
...  
Keyword(s):  
Yeast Artificial Chromosome ◽  
Genomic Analysis ◽  
Artificial Chromosome ◽  
Yeast Artificial Chromosome Library

scholarly journals An ordered yeast artificial chromosome library covering over half of rice chromosome 6.

1996 ◽  
Vol 6 (10) ◽  
pp. 935-942 ◽  
Author(s):  
Y Umehara ◽  
H Tanoue ◽  
N Kurata ◽  
I Ashikawa ◽  
Y Minobe ◽  
...  
Keyword(s):  
Yeast Artificial Chromosome ◽  
Rice Chromosome ◽  
Artificial Chromosome ◽  
Chromosome 6 ◽  
Yeast Artificial Chromosome Library
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