scholarly journals Inhaled versus systemic steroids in chronic oxygen dependency of preterm infants

1996 ◽  
Vol 156 (1) ◽  
pp. 51-55 ◽  
Author(s):  
G. Dimitriou ◽  
A. Greenough ◽  
F. J. Giffin ◽  
V. Kavadia
Keyword(s):  
Preterm Infants ◽  
Systemic Steroids ◽  
Chronic Oxygen Dependency

Outcomes of Infants Who Failed to Extubate despite Systemic Corticosteroids

2017 ◽  
Vol 34 (14) ◽  
pp. 1458-1463 ◽  
Author(s):  
Tamorah Lewis ◽  
Alexandra Oschman ◽  
Hong Dai ◽  
Katie Brophy ◽  
Michael Norberg ◽  
...  
Keyword(s):  
Preterm Infants ◽  
Retrospective Cohort ◽  
Primary Outcome ◽  
Extubation Failure ◽  
Tube Placement ◽  
Inclusion Criteria ◽  
Systemic Steroids ◽  
Systemic Corticosteroids ◽  
Gastrostomy Tube Placement ◽  
Prognostic Implications

Objective The objective of this study was to assess the outcomes of preterm infants who failed to extubate following initial treatment with steroids. Materials and Methods This is a retrospective cohort study of ventilator-dependent preterm infants treated with first course of systemic steroids to facilitate extubation. Outcomes of infants who successfully extubated were compared with infants who failed to extubate. Results In this study, 74 infants (mean gestation 25.4 ± 1.4 weeks and mean birth weight 764 ± 163 g) met inclusion criteria. Of these, 41 (55%) were successfully extubated and 33 (45%) were not. Baseline demographics were similar between the two groups. The primary outcome of severe bronchopulmonary dysplasia (BPD) or death at 36 weeks was higher among infants who failed to extubate (94 vs. 63%, p = 0.002). Severe BPD remained significantly higher even after adjustment for potential confounders (odds ratio: 12.2, 95% confidence interval: 2.1–70.5, p = 0.005). Extubation failure was also associated with substantially higher rate of tracheostomy (32 vs. 5%, p = 0.003) and gastrostomy tube placement (61 vs. 22%, p = 0.001), as well as longer days of hospitalization (179 ± 72 vs. 129 ± 44 days, p = 0.001) and mechanical ventilation (112 ± 89 vs. 52 ± 42 days, p < 0.001). Conclusion Failure to extubate after first course of systemic steroids for BPD is associated with poor prognostic implications.

Auditory Arousal in Preterm Infants

1984 ◽  
Vol 11 ◽  
pp. 3-9 ◽  
Author(s):  
Kay Lynn Copriviza ◽  
Cynthia Gayle Lima
Keyword(s):  
Preterm Infants

Spinal anaesthesia and meningitis in former preterm infants: cause-effect?

1999 ◽  
Vol 9 (3) ◽  
pp. 262-264 ◽  
Author(s):  
G Luz ◽  
H Buchele ◽  
P Innerhofer ◽  
H Maurer
Keyword(s):  
Preterm Infants ◽  
Spinal Anaesthesia

Safety of switching systemic steroids to budesonide modified-release capsules in steroid-dependent patients with inactive Crohn's disease

2001 ◽  
Vol 120 (5) ◽  
pp. A749-A749
Author(s):  
A CORTOT ◽  
J COLOMBEL ◽  
P RUTGEERTS ◽  
K LAURITSEN ◽  
H MALCHOW ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Modified Release ◽  
Systemic Steroids ◽  
Steroid Dependent
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