Recommendations for the reporting of tissues removed as part of the surgical treatment of cutaneous melanoma

1997 ◽  
Vol 431 (2) ◽  
pp. 79-81 ◽  
Author(s):  
A. J. Cochran
Keyword(s):  
Surgical Treatment ◽  
Cutaneous Melanoma

scholarly journals SURGICAL TREATMENT OF HEAD AND NECK CUTANEOUS MELANOMA: A MODERN APPROACH TO THE PROBLEM

2016 ◽  
Vol 6 (4) ◽  
pp. 19-25
Author(s):  
M. B. Pak ◽  
A. M. Mudunov ◽  
L. V. Demidov ◽  
R. I. Azizyan ◽  
V. Zh. Brzhezovskiy ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Modern Approach

scholarly journals Cutaneous Melanoma − Surgical Treatment

10.5772/54105 ◽  
2013 ◽  
Author(s):  
Mario Santinami ◽  
Roberto Patuzzo ◽  
Roberta Ruggeri ◽  
Gianpiero Castelli ◽  
Andrea Maurichi ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Cutaneous Melanoma

scholarly journals Primary Malignant Melanoma of Maxilla: Report of a Case with Discussion

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
G. Shirisha Rani ◽  
T. Vinay Kumar ◽  
Balaram Kolasani ◽  
Md Rezwana Begum ◽  
Anu Priya Srinivasan
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Oral Cavity ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Dental Clinic ◽  
Oral Melanoma ◽  
Pigmented Lesion ◽  
Oral Malignant Melanoma ◽  
Rule Out

Primary oral malignant melanoma, very rare neoplasm of melanocytic origin, usually presents as a bluish black to tan-brown colored lesion Which is accounting for 0.2 to 8% of all melanomas, 1.6% of all head and neck malignancies, and 0.5% of all oral neoplasia. In general, the prognosis of oral melanoma is poor and worse than that of cutaneous melanoma. Here a case of oral malignant melanoma is presented, which was undetected during the first visit to a dental clinic. When a simple oral surgical treatment was carried out in that region, it resulted in the appearance of a massive pigmented lesion which was histopathologically diagnosed as malignant melanoma. This paper is presented to reemphasize the fact that any pigmented lesion in the oral cavity should be viewed with suspicion and proper investigation (biopsy) should be carried out to rule out any untoward experiences later.

Positive Margins in Cutaneous Melanoma of the Head and Neck: Implications for Timing of Reconstruction

2020 ◽  
pp. 019459982096917
Author(s):  
Arya W. Namin ◽  
Lauren Welby ◽  
Austin T. Baker ◽  
Laura M. Dooley
Keyword(s):  
Surgical Treatment ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Spindle Cell ◽  
National Cancer Database ◽  
Clinicopathologic Features ◽  
Lentigo Maligna ◽  
Positive Margins ◽  
Lentigo Maligna Melanoma ◽  
The Face

Objective The aim of this study is to identify clinicopathologic features associated with positive margins after surgical treatment of cutaneous melanoma of the head and neck (CMHN). Study Design Retrospective cohort study. Setting National Cancer Database. Methods A retrospective analysis of the National Cancer Database was performed of patients diagnosed with CMHN between 2004 and 2016. Univariate and multivariate analyses examining the association of clinicopathologic features with positive margins were performed via logistic regression analysis. Results A total of 101,560 patients met inclusion criteria. The incidence of positive margins was 5.0% (5128/101,560). Patients were significantly more likely to have positive margins with the following: increasing age ( P < .001; odds ratio [OR], 1.028; 95% CI, 1.026-1.031), the lip subsite ( P < .001; OR, 1.664; 95% CI, 1.286-2.154), the eyelid subsite ( P < .001; OR, 2.380; 95% CI, 1.996-2.838), the face subsite ( P < .001; OR, 1.215; 95% CI, 1.133-1.302), the lentigo maligna/lentigo maligna melanoma subtype ( P = .019; OR, 1.099; 95% CI, 1.016-1.188), the desmoplastic subtype ( P < .001; OR, 1.455; 95% CI, 1.261-1.680), the spindle cell subtype ( P = .006; OR, 1.276; 95% CI, 1.073-1.516), and advanced pT classification. Patients with male sex ( P < .001; OR, 0.733; 95% CI, 0.687-0.782) and without ulceration ( P < .001; OR, 0.803; 95% CI, 0.736-0.876) were significantly less likely to have positive margins. Conclusion The following have been identified as clinicopathologic features associated with positive margins after surgical treatment of CMHN: increasing age, female sex, the lip subsite, the eyelid subsite, the face subsite, ulceration, the lentigo maligna/lentigo maligna melanoma subtype, the desmoplastic subtype, the spindle cell subtype, and increasing pT classification.

scholarly journals New Trends in Cutaneous Melanoma Surgery

2019 ◽  
Vol 7 (18) ◽  
pp. 3090-3092
Author(s):  
Jacopo Scala ◽  
Aleksandra Vojvodic ◽  
Petar Vojvodic ◽  
Tatjana Vlaskovic-Jovicevic ◽  
Zorica Peric-Hajzler ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Sentinel Node ◽  
Surgical Management ◽  
Cutaneous Melanoma ◽  
Surgical Excision ◽  
Primary Lesion ◽  
Braf Inhibitors ◽  
Advanced Stages ◽  
Systemic Therapies

The main surgical treatment for melanoma consists in wide surgical excision of the primary lesion and the sentinel node but in recent times management of melanoma is rapidly evolving with the introduction of new systemic therapies, like BRAF inhibitors, MEK inhibitors and antibodies anti-PD-1 that show good results in controlling even advanced stages of the disease. This review aims to present data for the optimal surgical management of patients with malignant melanoma.

scholarly journals Recommendations for the Reporting of Tissues Removed as Part of the Surgical Treatment of Cutaneous Melanoma

1998 ◽  
Vol 110 (6) ◽  
pp. 719-722 ◽  
Author(s):  
Alistair J. Cochran ◽  
Christiane Bailly ◽  
Martin Cook ◽  
Kerry Crotty ◽  
Stan McCarthy ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Cutaneous Melanoma

Surgical Treatment of Gastric Metastases from Cutaneous Melanoma: Experience of the National Cancer Institute of Milan

2001 ◽  
Vol 87 (4) ◽  
pp. 229-231 ◽  
Author(s):  
Gianfrancesco Gallino ◽  
Filiberto Belli ◽  
Giuliano Bonfanti ◽  
Antonino Ditto ◽  
Salvatore Andreola ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
National Cancer Institute ◽  
Cutaneous Melanoma ◽  
Gastric Metastases

scholarly journals Does morphology have real impact on local and distant recurrences in head and neck cutaneous melanoma?

2020 ◽  
Vol 10 (3) ◽  
pp. 55-64
Author(s):  
A. M. Mudunov ◽  
M. B. Pak ◽  
L. V. Demidov ◽  
K. A. Baryshnikov
Keyword(s):  
Prognostic Factors ◽  
Surgical Treatment ◽  
Local Recurrence ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Primary Tumor ◽  
Resection Margin ◽  
Tumor Thickness ◽  
Treatment Results ◽  
Level Of Invasion

Introduction. The term “local recurrence” is usually understood as regrowth of a tumor after surgical treatment. The regrowth appears within 3–5 cm from postoperative cicatrix. The causes for such prolonged tumor growth or recurrence of patients with cutaneous melanoma are nonradical surgical treatment as well as satellite or transit metastases that were not removed in-block with primary tumor. A great number of clinical researches, aimed at examination of melanoma, its patterns, anatomical criteria and features of clinical course, gave an opportunity to separate satellite or transit metastases into an independent group. Such metastases are realized inside or subdermally, up to 2 cm or more than 2 cm from the primary tumor, yet, not reaching the location of the first regional barrier.The aim of the study is to define influence of the main prognostic factors such as tumor thickness according to Breslow, the level of invasion according to Clark and the presence of ulceration on the frequency of local recurrence with cutaneous melanoma of head and neck.Materials and methods. The research involved 174 patients with cutaneous melanoma of head and neck (1995–2014). According to our index of contraction of a skin flap (median 30 %) the true borders of resection were clearly defined within all the patients. Thereby, 3 groups were identified with the following resection margin: 1.0 cm, where followed-up treatment results were analyzed.Results. Progression-free survival didn’t correlate with the size of surgical resection margins. The survival rates were the best with the lowest resection margin under 0.5 cm (77.3 %) and the worst with the highest resection margin more then 1.0 cm (38.7 %). That means that the treatment results don’t depend on the width increase of tumor resection margin.Conclusions. We consider that clear surgical margins for any thickness of cutaneous melanoma of head and neck should be as follows: 4 mm – 0.72 mm (p = 0.016). In our work, the influence of the main prognostic factors, such as tumor thickness according to Breslow, level of invasion according to Clark and ulceration on the frequency of head and neck cutaneous melanoma local recurrences had no impact.

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