The biological zero signal in laser doppler fluximetry - origins and practical implications

1999 ◽  
Vol 437 (4) ◽  
pp. 624-631 ◽  
Author(s):  
D. P. Kernick ◽  
J. E. Tooke ◽  
A. C. Shore
Keyword(s):  
Laser Doppler ◽  
Laser Doppler Fluximetry ◽  
Practical Implications

METHOD OPTIMISATION ON THE USE OF LASER DOPPLER FLUXIMETRY TO ASSESS SKIN MACROVASCULAR ENDOTHELIAL FUNCTION

2004 ◽  
Vol 22 (Suppl. 1) ◽  
pp. S42
Author(s):  
G. B. Tee ◽  
A H.G. Rasool ◽  
A S. Halim ◽  
A RA. Rashid
Keyword(s):  
Endothelial Function ◽  
Laser Doppler ◽  
Laser Doppler Fluximetry

Changes in Skin Microcirculation at Periulcerous Sites in Patients with Chronic Venous Ulcers during Leg Elevation

1992 ◽  
Vol 7 (1) ◽  
pp. 36-39 ◽  
Author(s):  
M. D. Barnes ◽  
R. Mani ◽  
D. F. Barrett ◽  
J. E. White
Keyword(s):  
Lower Limb ◽  
Laser Doppler ◽  
Lower Limbs ◽  
Patient Treatment ◽  
Venous Ulceration ◽  
Transcutaneous Oxygen ◽  
Venous Ulcers ◽  
Laser Doppler Fluximetry ◽  
Transcutaneous Oximetry ◽  
Oxygen Measurements

Objective: To investigate the effect of limb elevation on the microcirculation of the skin in patients with venous ulceration of the leg. Design: Prospective study in patients receiving in patient treatment for venous ulceration. Setting: Health Service teaching hospital. Patients: Thirteen patients with venous ulceration of the lower limb for more than two years were investigated. Interventions: Patients were admitted to hospital and treated by bedrest with elevation of the lower limbs by 10° above the horizontal. Main outcome measures: Laser Doppler fluximetry and transcutaneous oximetry of the skin surrounding the venous ulcers was undertaken. Results: The laser Doppler fluximetry in the periculcerous region increased by 10.8 A.U. (95% CI 17 to 4.54). However, the transcutaneous oxygen measurements did not change during the period of treatment. Conclusions: Admission to hospital with elevation of the limb for patients with venous ulceration results in ***microcirculatory changes which are probably attributable to reduction in lower limb oedema.

Laser-Doppler measurements of concentration and velocity of moving blood cells in rat cerebral circulation

1997 ◽  
Vol 160 (1) ◽  
pp. 123-132
Author(s):  
C. BARFOD ◽  
N. AKGÖREN ◽  
M. FABRICIUS ◽  
U. DIRNAGL ◽  
M. LAURITZEN
Keyword(s):  
Blood Cells ◽  
Cerebral Circulation ◽  
Laser Doppler

The response of skin perfusion and of rheological and immunological variables to intravenous prostanoid administration in Raynaud’s phenomenon secondary to collagenosis

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 243-249 ◽  
Author(s):  
Drinda ◽  
Neumann ◽  
Pöhlmann ◽  
Vogelsang ◽  
Stein ◽  
...  
Keyword(s):  
Laser Doppler Flowmetry ◽  
Raynaud’S Phenomenon ◽  
Raynaud's Phenomenon ◽  
Plasma Viscosity ◽  
Laser Doppler ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Long Term Effects ◽  
Doppler Flowmetry

Background: Prostanoids are used in the treatment of Raynaud’s phenomenon and acral perfusion disorders secondary to collagenosis. In subjective terms, intravenous administration of these agents produces success in more than 50% of patients. The therapeutic outcome of clinical administration of alprostadil or iloprost may vary from individual to individual. Patients and methods: The following variables were analysed in a cross-over study in 27 patients with collagenosis and Raynaud’s phenomenon: plasma viscosity and erythrocyte aggregation (rheological variables), partial pressure of oxygen and laser Doppler flowmetry in the finger region, and lymphocyte phenotyping and interleukin (IL) determinations (immunological variables). Results: Laser Doppler flowmetry revealed significant differences between patients with secondary Raynaud’s phenomenon and a control group of 25 healthy subjects. Laser Doppler readings did not change significantly as a result of the treatments. Therapy with iloprost produced a reduction in IL-1beta, L-selectin (CD 62 L) and IL-6. Conclusion: The change in immunological variables due to iloprost may explain the long-term effects of prostaglandins in the treatment of Raynaud’s phenomenon. From our results it is not possible to infer any preference for iloprost or alprostadil.

The Differential Effectiveness of the Cognitive Interview Instructions for Enhancing Witnesses’ Memory of a Familiar Event

2014 ◽  
Vol 73 (1) ◽  
pp. 25-34 ◽  
Author(s):  
Magali Ginet ◽  
Jacques Py ◽  
Cindy Colomb
Keyword(s):  
Cognitive Interview ◽  
Critical Event ◽  
Surgical Operation ◽  
Differential Effectiveness ◽  
Correct Information ◽  
Control Instruction ◽  
The Individual ◽  
Practical Implications

This study examines the influence of familiarity on witnesses’ memory and the individual effectiveness of each of the four cognitive interview instructions in improving witnesses’ recall of scripted events. Participants (N = 195), either familiar or unfamiliar with the hospital script, were presented with a video of a surgical operation. One week later, an interviewer used one of the four cognitive interview instructions or a control instruction to ask them about the video. Participants familiar with the surgery context recalled significantly more correct information and, in particular, more consistent and irrelevant details than those unfamiliar with the surgery context. Furthermore, the results confirmed the effectiveness of all four cognitive interview mnemonics in enhancing the amount of correct information reported, irrespective of the participants’ familiarity with the critical event. However, their efficacy differed depending on the category of details considered. The practical implications of these results are discussed.

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