Effect of acetazolamide on cerebral blood flow and tympanic temperature in healthy subjects and patients with subacute subarachnoid haemorrhage

1997 ◽  
Vol 75 (3) ◽  
pp. 252-255 ◽  
Author(s):  
Fumihiko Sugino ◽  
Tokuo Ogawa ◽  
Satoshi Umemura ◽  
Satoru Suzuki ◽  
Yasuhiro Kawamura
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Haemorrhage ◽  
Healthy Subjects ◽  
Tympanic Temperature

scholarly journals Can Cerebral Blood Volume Be Measured Reproducibly with an Improved near Infrared Spectroscopy System?

2001 ◽  
Vol 21 (2) ◽  
pp. 110-113 ◽  
Author(s):  
Marjo J. T. Van de Ven ◽  
Willy N. J. M. Colier ◽  
Marco C. van der Sluijs ◽  
Diederik Walraven ◽  
Berend Oeseburg ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Infrared Spectroscopy ◽  
Blood Volume ◽  
Near Infrared Spectroscopy ◽  
Healthy Subjects ◽  
Baseline Level ◽  
Near Infrared ◽  
Cerebral Blood Volume ◽  
Spectroscopy System

In some circumstances, cerebral blood volume (CBV) can be used as a measure for cerebral blood flow. A new near infrared spectroscope was used for determining the reproducibility of CBV measurements assessed by the O2-method. Twenty-seven healthy subjects were investigated. An intrasubject coefficient of variation (CV) was calculated, based on four identical episodes of desaturation–resaturation (O2-method) procedures for CBV measurements. Two trials were performed, with (trial 1) and without (trial 2) disconnecting the equipment. A mean CV of 12.6% and 10.0% was found in trial 1 and 2, respectively. Cerebral blood volume values yield 3.60 ± 0.82 mL 100 g−1. Cerebral blood volume could be measured reproducible in adults using near infrared spectroscopy, if the arterial desaturation is limited to approximately 5% from baseline level.

Abstract WP322: Inhaled Nitric Oxide Augments Cerebral Blood Flow in Healthy Subjects

Stroke ◽  
2018 ◽  
Vol 49 (Suppl_1) ◽  
Author(s):  
Christopher G Favilla ◽  
Rodrigo M Forti ◽  
Ahmad Zamzam ◽  
John A Detre ◽  
Michael T Mullen ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Healthy Subjects ◽  
Inhaled Nitric Oxide

scholarly journals Can interhemispheric desynchronization of cerebral blood flow anticipate upcoming vasospasm in aneurysmal subarachnoid haemorrhage patients?

2019 ◽  
Vol 325 ◽  
pp. 108358
Author(s):  
Michał M. Placek ◽  
Peter Smielewski ◽  
Paweł Wachel ◽  
Karol P. Budohoski ◽  
Marek Czosnyka ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Haemorrhage ◽  
Aneurysmal Subarachnoid Haemorrhage

scholarly journals MP09-13 QUANTIFICATION OF CEREBRAL BLOOD FLOW DURING BLADDER FILLING IN HEALTHY SUBJECTS

2018 ◽  
Vol 199 (4S) ◽  
Author(s):  
Justina Tam ◽  
Kenneth Wengler ◽  
Jason Kim ◽  
Wayne Waltzer ◽  
Xiang He ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Healthy Subjects ◽  
Bladder Filling

Postoperative assessment of cerebral blood flow in subarachnoid haemorrhage by means of99mTc-HMPAO tomography

1993 ◽  
Vol 20 (1) ◽  
pp. 53-58 ◽  
Author(s):  
F. Tranquart ◽  
P. E. Ades ◽  
P. Groussin ◽  
J. F. Rieant ◽  
M. Jan ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Subarachnoid Haemorrhage ◽  
Postoperative Assessment

scholarly journals Acute hypoxia increases the cerebral metabolic rate – a magnetic resonance imaging study

2015 ◽  
Vol 36 (6) ◽  
pp. 1046-1058 ◽  
Author(s):  
Mark B Vestergaard ◽  
Ulrich Lindberg ◽  
Niels Jacob Aachmann-Andersen ◽  
Kristian Lisbjerg ◽  
Søren Just Christensen ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Magnetic Resonance ◽  
Metabolic Rate ◽  
Oxygen Saturation ◽  
Healthy Subjects ◽  
Acute Hypoxia ◽  
Resonance Imaging ◽  
Cerebral Metabolic Rate

The aim of the present study was to examine changes in cerebral metabolism by magnetic resonance imaging of healthy subjects during inhalation of 10% O2 hypoxic air. Hypoxic exposure elevates cerebral perfusion, but its effect on energy metabolism has been less investigated. Magnetic resonance imaging techniques were used to measure global cerebral blood flow and the venous oxygen saturation in the sagittal sinus. Global cerebral metabolic rate of oxygen was quantified from cerebral blood flow and arteriovenous oxygen saturation difference. Concentrations of lactate, glutamate, N-acetylaspartate, creatine and phosphocreatine were measured in the visual cortex by magnetic resonance spectroscopy. Twenty-three young healthy males were scanned for 60 min during normoxia, followed by 40 min of breathing hypoxic air. Inhalation of hypoxic air resulted in an increase in cerebral blood flow of 15.5% ( p = 0.058), and an increase in cerebral metabolic rate of oxygen of 8.5% ( p = 0.035). Cerebral lactate concentration increased by 180.3% ([Formula: see text]), glutamate increased by 4.7% ([Formula: see text]) and creatine and phosphocreatine decreased by 15.2% ( p[Formula: see text]). The N-acetylaspartate concentration was unchanged ( p = 0.36). In conclusion, acute hypoxia in healthy subjects increased perfusion and metabolic rate, which could represent an increase in neuronal activity. We conclude that marked changes in brain homeostasis occur in the healthy human brain during exposure to acute hypoxia.

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