Detection of polycyclic aromatic hydrocarbon metabolites by high-pressure liquid chromatography after purification on immunoaffinity columns in urine from occupationally exposed workers

1999 ◽  
Vol 72 (3) ◽  
pp. 161-168 ◽  
Author(s):  
R. K. Bentsen-Farmen ◽  
I. V. Botnen ◽  
H. Notø ◽  
J. Jacob ◽  
S. ØvrebØ
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Polycyclic Aromatic Hydrocarbon ◽  
Aromatic Hydrocarbon ◽  
High Pressure Liquid Chromatography ◽  
Exposed Workers ◽  
Occupationally Exposed ◽  
Polycyclic Aromatic ◽  
Immunoaffinity Columns

Polycyclic Aromatic Hydrocarbon Carcinogens in Commercial Seafoods

1979 ◽  
Vol 36 (12) ◽  
pp. 1469-1476 ◽  
Author(s):  
Bruce P. Dunn ◽  
John Fee
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
Polycyclic Aromatic Hydrocarbon ◽  
Aromatic Hydrocarbon ◽  
Maximum Level ◽  
Polynuclear Aromatic Hydrocarbon ◽  
Polycyclic Aromatic ◽  
Wet Weight ◽  
Carcinogenic Hydrocarbons ◽  
Exogenous Source

Fresh and processed commercial seafoods were analyzed for the polycyclic aromatic hydrocarbon carcinogen benzo(a)pyrene using a thin-layer chromatographic separation technique and quantitation by fluorescence. Commercial samples of vertebrate fish did not contain detectable levels, except where fish were packed with vegetable oil, an exogenous source of carcinogens. Levels in most shellfish samples were generally less than 10 ng/g wet weight, but occasional samples contained up to 36 ng/g. Crab and shrimp samples contained little or no benzo(a)pyrene (ND to 0.5 ng/g). Commercial lobsters contained 0.8 to 7.9 ng/g. The source of contamination of lobsters was further investigated, utilizing high pressure liquid chromatography to measure 13 polycyclic aromatic hydrocarbon isomers. Freshly caught lobsters had less than 1 ng/g benzo(a)pyrene. Lobsters which had been kept in a commercial tidal pound constructed of creosoted timber contained highly elevated levels of benzo(a)pyrene and other carcinogenic hydrocarbons, including chrysene, benzo(a)anthracene, benzo(b)fluoranthene, dibenz(a,h)anthracene, and indeno(1,2,3-cd)pyrene The maximum level of benzo(a)pyrene was 2300 ng/g wet weight in digestive gland, and 281 ng/g in edible tail meat. These levels are substantially higher than previously reported for any foodstuff, and are most probably attributable to creosote contamination during impoundment. Key words: benzo(a)pyrene, polycyclic (polynuclear) aromatic hydrocarbon, carcinogen, seafood, lobster, shellfish, creosote

Sources of polycyclic aromatic hydrocarbon exposure in non-occupationally exposed Koreans

2003 ◽  
Vol 42 (4) ◽  
pp. 250-257 ◽  
Author(s):  
Mihi Yang ◽  
Soyeon Kim ◽  
Eunil Lee ◽  
Hae-Kwan Cheong ◽  
Seong-Sil Chang ◽  
...  
Keyword(s):  
Polycyclic Aromatic Hydrocarbon ◽  
Aromatic Hydrocarbon ◽  
Occupationally Exposed ◽  
Polycyclic Aromatic
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