Correlation between tear IgE levels and HLA-DR expression by conjunctival cells in allergic and nonallergic chronic conjunctivitis

2000 ◽  
Vol 238 (11) ◽  
pp. 900-904 ◽  
Author(s):  
C. Baudouin ◽  
T. Bourcier ◽  
F. Brignole ◽  
F. Bertel ◽  
M. Moldovan ◽  
...  
Keyword(s):  
Hla Dr ◽  
Conjunctival Cells ◽  
Chronic Conjunctivitis

Is there a role for tapered topical dose steroidal treatment for dry eye disease? A randomized, pilot study

2021 ◽  
pp. 112067212110487
Author(s):  
Stefano Barabino ◽  
Elisa Montaldo ◽  
Maria Cristina Mingari ◽  
Cosimo Mazzotta ◽  
Sebastiano Giuffrida ◽  
...  
Keyword(s):  
Dry Eye ◽  
Ocular Surface ◽  
Dry Eye Disease ◽  
Eye Disease ◽  
Loteprednol Etabonate ◽  
Hla Dr ◽  
Eye Symptoms ◽  
Conjunctival Cells ◽  
Surface Inflammation ◽  
Ocular Surface Inflammation

Purpose: To evaluate the effect of tapered doses of loteprednol-etabonate in dry eye disease patients. Materials and methods: Dry eye and treatment outcomes were assessed by Schirmer I test, tear BUT, lissamine green conjunctival staining, fluorescein corneal staining, and HLA-DR expression on conjunctival cells. Patients received either loteprednol-etabonate 0.5% twice daily for 14 days tapered to once daily for 14 days, and then twice weekly for 28 days ( n = 10), or NaCl 0.9%. Results: A significant decrease of ocular surface inflammation and improvement of symptoms was recorded in the study group compared with controls at days 14 and 56. Change from baseline in HLA-DR expression in CD45+ conjunctival cells was significantly higher in treated patients at day 14. Intraocular pressure and best corrected visual acuity were preserved in all treated eyes. Conclusions: Tapered doses of loteprednol etabonate 0.5% suspension controlled ocular surface inflammation, improving dry eye symptoms.

HLA-DR Expression in Conjunctival Cells After Latanoprost

2002 ◽  
Vol 18 (1) ◽  
pp. 1-9 ◽  
Author(s):  
Elena Guglielminetti ◽  
Stefano Barabino ◽  
Marina Monaco ◽  
Stefano Mantero ◽  
Maurizio Rolando
Keyword(s):  
Hla Dr ◽  
Conjunctival Cells

Alendronate Stimulates Expression of Functional Surface Molecules ICAM-1, HLA-DR, and B7-2 on Human Monocytes

2006 ◽  
Vol 15 (03) ◽  
pp. 188-196
Author(s):  
S. Brosch ◽  
M. Shehata ◽  
G. Hofbauer ◽  
M. Peterlik ◽  
P. Pietschmann
Keyword(s):  
Human Monocytes ◽  
Functional Surface ◽  
Surface Molecules ◽  
Hla Dr

Age-dependent differences in postoperative HLA-DR expression in cardiac surgery patients

2011 ◽  
Vol 59 (S 01) ◽  
Author(s):  
K Lazouski ◽  
A Zittermann ◽  
M Schmidt ◽  
J Gummert ◽  
J Börgermann
Keyword(s):  
Cardiac Surgery ◽  
Hla Dr ◽  
Age Dependent

Relationship of Major Histocompatibility Complex Class II Genes to Inhibitor Antibody Formation in Hemophilia A

1990 ◽  
Vol 64 (04) ◽  
pp. 564-568 ◽  
Author(s):  
Lloyd E Lippert ◽  
Lyman Mc A Fisher ◽  
Lawrence B Schook
Keyword(s):  
Major Histocompatibility Complex ◽  
Factor Viii ◽  
Antibody Formation ◽  
Rflp Analysis ◽  
Class Ii ◽  
Major Histocompatibility ◽  
Odds Ratios ◽  
Inhibitory Antibody ◽  
Histocompatibility Complex ◽  
Hla Dr

SummaryApproximately 14% of transfused hemophiliacs develop an anti-factor VIII inhibitory antibody which specifically neutralizes factor VIII procoagulant activity. In this study an association of the major histocompatibility complex (MHC) with inhibitor antibody formation was evaluated by restriction fragment length polymorphism (RFLP) analysis using BamHI, EcoRI, HindII, PstI, PvuII and TaqI digested genomic DNA probed with DP beta, DQ alpha, DQ beta and DR beta class II MHC gene probes. The RFLP patterns for 16 non-inhibitor and 11 inhibitor hemophiliac patients were analyzed. These 24 enzyme:probe combinations generated 231 fragments. Fifteen (15) fragments associated with the inhibitor phenotype; odds ratios ranged from 5.1 to 45 and lower bounds of 95% confidence intervals were > 1.000 for all 15 fragments. Five (5) fragments associated with non-inhibitors, with odds ratios ranging from 6.4 to 51.7. This report establishes a MHC related genetic basis for the inhibitor phenotype. No statistically significant differences in the distribution of serologically defined HLA-DR phenotypes were observed between the inhibitor and non-inhibitor groups.

Quantitative Messung der monozytären HLA-DR Expression bei gesunden Neugeborenen

2004 ◽  
Vol 208 (S 1) ◽  
Author(s):  
T Spreemann ◽  
B Spring ◽  
CF Poets ◽  
T Orlikowsky
Keyword(s):  
Hla Dr

Effects of thyrocytes on intrathyroidal HLA-DR+ lymphocytes and CD94+ NK cells in vitro differ depending on thyroid disease

2005 ◽  
Vol 113 (S 1) ◽  
Author(s):  
M Penna-Martinez ◽  
K Andric ◽  
RA Wahl ◽  
KH Usadel ◽  
PM Schumm-Draeger
Keyword(s):  
Nk Cells ◽  
Thyroid Disease ◽  
Hla Dr
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