De novo formation of a megadolichobasilar artery associated with bilateral fusiform aneurysms of the internal carotid artery

1999 ◽  
Vol 246 (3) ◽  
pp. 224-225 ◽  
Author(s):  
R. M. J. A. Roebroek ◽  
J. W. M. ter Berg ◽  
R. T. van der Laan
Neurosurgery ◽  
1991 ◽  
Vol 29 (5) ◽  
pp. 756-759 ◽  
Author(s):  
Robin F. Koeleveld ◽  
Carl B. Heilman ◽  
Richard P. Klucznik ◽  
William A. Shucart

Abstract A case of the de novo formation of an aneurysm in a young woman is presented. At age 13 years, she had a spontaneous subarachnoid hemorrhage. Cerebral angiography showed an aneurysm of the bifurcation of the left internal carotid artery and a small aneurysm of the left anterior choroidal artery. At surgery, the aneurysm of the internal carotid artery was clipped, and the aneurysm of the left anterior choroidal artery was wrapped with muslin. Thirteen years later, the patient had another subarachnoid hemorrhage. Cerebral arteriography showed four aneurysms that had developed at previously angiographically normal sites. This case suggests that young patients with aneurysms might benefit from follow-up angiography in search of late aneurysm formation.


2019 ◽  
Vol 131 (5) ◽  
pp. 1481-1484
Author(s):  
Giovanni G. Vercelli ◽  
Norbert G. Campeau ◽  
Thanila A. Macedo ◽  
Elliot T. Dawson ◽  
Giuseppe Lanzino

A carotid web is a shelf-like intraluminal filling defect typically arising from the posterolateral wall of the proximal internal carotid artery. It is recognized as a possible cause of ischemic stroke in young adults. However, its etiopathogenesis is controversial and remains to be fully elucidated. The authors report de novo formation of a carotid web from an intimal dissection documented on serial imaging studies. The findings in this case suggest that a focal intimal dissection could be the underlying cause of a carotid web. Lower shear stress at the posterolateral wall of the proximal internal carotid artery is hypothesized to be a predisposing factor and explains the predilection of a carotid web for this specific location.


2021 ◽  
pp. 159101992110017
Author(s):  
Waleed Butt ◽  
Luqman Malik ◽  
Permesh Singh Dhillon ◽  
Norman McConachie

Background Aneurysm formation after internal carotid artery (ICA) occlusion has been described in animal models and human case series with alteration of cerebral blood flow dynamics considered an aetiological risk factor. Such de novo aneurysms have seldom been described in the posterior cerebral artery (PCA) with the majority observed in the anterior circulation collateral pathways. Methods We retrospectively reviewed our institutional database of posterior circulation aneurysms in patients with iatrogenic, atherosclerotic or congenital ICA occlusions. A comprehensive review of the online literature using the PubMed and Medline databases was performed to identify previous cases of PCA aneurysms that were considered ‘flow-related’. Results We present five patients with symptomatic or ruptured PCA aneurysms with ICA occlusions. Age at presentation ranged from 21-58 and aneurysm size from 3–12 mm. All cases had angiographic evidence of posterior-anterior flow via the ipsilateral posterior communicating artery (PComA). The clinical presentation, diagnostic imaging and management strategies are further discussed. A literature review identified only two previous reported cases. Conclusion To our knowledge this is the first single centre series of posterior circulation aneurysms in patients with ICA occlusions that are considered to be ‘flow-related.’ The natural history of these rare lesions is unclear and the best management and surveillance strategy requires a patient-tailored approach by an experienced neurovascular team.


Stroke ◽  
2017 ◽  
Vol 48 (suppl_1) ◽  
Author(s):  
Satoshi Kuroda ◽  
Kuniaki Ogasawara ◽  
Masaaki Uno ◽  

Background and Purpose: Previous clinical trials have shown that clinical benefits of carotid endarterectomy (CEA) are unclear in symptomatic mild (<50%) stenosis of the internal carotid artery. However, it is not rare that the patients with mild carotid stenosis repeat TIA or ischemic stroke in spite of the best medical treatments. Although only the degree of stenosis have been accepted as “gold standard” in deciding treatment strategy, recent development of non-invasive MR imaging enables us to identify unstable plaque. Therefore, we have designed “ M ild, but U nstable S tenosis of I nternal C arotid artery (MUSIC) Study” in Japan. The objectives of this nation-wide, multicenter prospective study are to clarify the prognosis of patients with symptomatic mild carotid stenosis and identify the predictors for the patients at higher risk for recurrent TIA and ischemic stroke in spite of the best medical treatments. Impact of CEA is also evaluated in those refractory to the best medical treatments. Methods and Results: MUSIC Study is conducted in Japan, using a multi-center prospective observational design (UMIN000023635). The MUSIC Study Group is composed of 28 hospitals. This study will register totally 250 patients who are 20 years or older, experience TIA, ischemic stroke, or retinal ischemia in the ipsilateral carotid territory, have mild (<50%) stenosis in the ipsilateral cervical carotid artery, and are independent in daily life (modified Rankin scale=0-2). Using MRI, plaque components are precisely evaluated in all patients. After informed consent is obtained, their clinical and radiological data are registered. They are followed up for two years and MRI/MRA examinations are repeated at 6, 12, and 24 months after the enrollment. Primary endpoint includes the incidence of ischemic stroke in the ipsilateral carotid territory. Secondary endpoints include the incidence of all-ischemic stroke, ipsilateral or all TIA, ipsilateral or all retina ischemia, all stroke, all death, de novo silent cerebral infarct, and progression of carotid stenosis. Conclusion: In this conference, we emphasize the importance to identify the patients at higher risk for recurrent ischemic events due to symptomatic mild carotid stenosis in spite of the best medical treatments.


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