Projection of cancer risks from the Japanese atomic bomb survivors to the England and Wales population taking into account uncertainty in risk parameters

2000 ◽  
Vol 39 (4) ◽  
pp. 241-252 ◽  
Author(s):  
M. P. Little ◽  
I. Deltour ◽  
S. Richardson
Keyword(s):  
Atomic Bomb ◽  
Cancer Risks ◽  
England And Wales ◽  
Atomic Bomb Survivors ◽  
Risk Parameters

scholarly journals Benchmarking Risk Predictions and Uncertainties in the NSCR Model of GCR Cancer Risks with Revised Low LET Risk Coefficients

2020 ◽  
Author(s):  
Francis A. Cucinotta ◽  
Eliedonna Cacao ◽  
Myung-Hee Y. Kim ◽  
Premkumar B. Saganti
Keyword(s):  
Atomic Bomb ◽  
International Study ◽  
Cosmic Ray ◽  
Space Radiation ◽  
Quality Factors ◽  
Cancer Risks ◽  
Organ Doses ◽  
Atomic Bomb Survivors ◽  
High Let ◽  
Galactic Cosmic Ray

AbstractWe report on the contributions of model factors that appear in fatal cancer risk projection models to the overall uncertainty in cancer risks predictions for exposures to galactic cosmic ray (GCR) in deep space. Annual GCR exposures to astronauts at solar minimum are considered. Uncertainties in low LET risk coefficients, dose and dose-rate modifiers, quality factors (QFs), space radiation organ doses, non-targeted effects (NTE) and increased tumor lethality at high LET compared to low LET radiation are considered. For the low LET reference radiation parameters we use a revised assessment of excess relative risk (ERR) and excess additive risk (EAR) for radiation induced cancers in the Life-Span Studies (LSS) of the Atomic bomb survivors that was recently reported, and also consider ERR estimates for males from the International Study of Nuclear Workers (INWORKS). For 45-y old females at mission age the risk of exposure induced death (REID) per year and 95% confidence intervals is predicted as 1.6% [0.71, 1.63] without QF uncertainties and 1.64% [0.69, 4.06] with QF uncertainties. However, fatal risk predictions increase to 5.83% [2.56, 9.7] with non-targeted effects. For males a comparison application to GCR using LSS or INWORKS lead to predictions of 1.24% [0.58, 3.14] and 2.45% [1.23, 5.9] without NTEs. The major conclusion of our report is that high LET risk prediction uncertainties due to QFs parameters, NTEs, and possible increase lethality at high LET are dominant contributions to GCR uncertainties and should be the focus of space radiation research.

P07: Gastric cancer risks among atomic-bomb survivors differ by HLA class I genotype

2009 ◽  
Vol 61 (3) ◽  
pp. 284-285
Author(s):  
Tomonori Hayashi ◽  
Hiroko Nagamura ◽  
Yukari Morishita ◽  
Mayumi Maki ◽  
Misae Sora ◽  
...  
Keyword(s):  
Gastric Cancer ◽  
Atomic Bomb ◽  
Hla Class I ◽  
Class I ◽  
Cancer Risks ◽  
Atomic Bomb Survivors

Skin cancer of Nagasaki atomic bomb survivors. II. Cases in the three major hospitals of Nagasaki city.

1990 ◽  
Vol 52 (1) ◽  
pp. 71-75
Author(s):  
Naoki SADAMORI ◽  
Mariko MINE ◽  
Makoto HORI ◽  
Naoko FUJIWARA ◽  
Osamu TAKAHARA ◽  
...  
Keyword(s):  
Skin Cancer ◽  
Atomic Bomb ◽  
Atomic Bomb Survivors

scholarly journals Autoantibodies and Immunoglobulins in Atomic Bomb Survivors with Human T-Lymphotropic Virus Type I.

1996 ◽  
Vol 35 (8) ◽  
pp. 624-628 ◽  
Author(s):  
Kiyosumi OHISHI ◽  
Yoshisada SHIBATA ◽  
Tatsufumi NAKAMURA ◽  
Mitsuhiro TSUJIHATA ◽  
Masazumi AKAHOSHI ◽  
...  
Keyword(s):  
Virus Type ◽  
Atomic Bomb ◽  
Type I ◽  
T Lymphotropic Virus ◽  
Atomic Bomb Survivors

The long-term outcome of atomic bomb survivors with gastric carcinoma

2009 ◽  
Vol 100 (7) ◽  
pp. 594-597 ◽  
Author(s):  
Manabu Yamamoto ◽  
Ayumi Matsuyama ◽  
Toshifumi Kameyama ◽  
Masahiro Okamoto ◽  
Jin Okazaki ◽  
...  
Keyword(s):  
Gastric Carcinoma ◽  
Atomic Bomb ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Atomic Bomb Survivors
Sign in / Sign up

Export Citation Format

Share Document