Long-term follow-up of the clinical relevance of short outer dynein arms in human nasal cilia

1998 ◽  
Vol 255 (10) ◽  
pp. 495-498 ◽  
Author(s):  
T. Torkkeli ◽  
M. Rautiainen ◽  
J. Nuutinen
Keyword(s):  
Clinical Relevance ◽  
Long Term Follow Up ◽  
Dynein Arms ◽  
Nasal Cilia

Clinical Relevance of Neovascularisation on Duplex Ultrasound in the Long-Term Follow-up after Varicose Vein Operation

1999 ◽  
Vol 14 (3) ◽  
pp. 118-122 ◽  
Author(s):  
M. G. De Maeseneer ◽  
I. F. Tielliu ◽  
P. E. Van Schil ◽  
S. G. De Hert ◽  
E. J. Eyskens
Keyword(s):  
Varicose Vein ◽  
Clinical Relevance ◽  
Varicose Veins ◽  
University Hospital ◽  
Duplex Scanning ◽  
Recurrent Varicose Veins ◽  
Varicose Vein Operation ◽  
Long Term Follow Up

Objective: To evaluate the clinical relevance of neovascularisation at the saphenous ligation site. Design: Long-term follow-up after previous varicose vein surgery in a single patient group. Setting: Vascular clinic of a university hospital. Patients: Eighty-two patients (106 limbs) with a mean follow-up period of 56 months after correct saphenous ligation were submitted to duplex scanning. Intervention: Clinical assessment and colour duplex scanning of all the operated limbs. Reintervention in 15 limbs with perioperative evaluation of recurrent veins. Main outcome measures: Limbs with and without recurrent varicose veins were classified according to the degree of neovascularisation: grade 0 = no new communicating veins, grade 1 = tiny new vein with diameter <4 mm, grade 2 = new communicating vein with diameter >4 mm and pathological reflux. On reintervention the presence of neovascular veins at the site of the previous ligation was checked. Results: In 68 limbs without recurrent varicose veins, grade 0 was observed in 50 limbs (74%), grade 1 in 12 limbs (18%) and grade 2 in six limbs (9%). In 38 limbs with recurrent varicose veins, grade 0 was diagnosed in eight limbs (21%), grade 1 in four limbs (11%) and grade 2 in 26 limbs (68%). In 15 limbs with recurrent varicose veins and grade 2 neovascularisation, reintervention confirmed the duplex findings. Conclusions: The presence of grade 2 neovascularisation was associated with the recurrence of varicose veins, suggesting a causal relationship.

Peri-implant disease part 1: diagnosis and assessment parameters

Dental Update ◽  
2019 ◽  
Vol 46 (10) ◽  
pp. 978-985
Author(s):  
Alex Daly ◽  
Giles McCracken
Keyword(s):  
Quality Of Life ◽  
Patient Satisfaction ◽  
Dental Implants ◽  
Clinical Relevance ◽  
Assessment Criteria ◽  
Maintenance Care ◽  
Long Term Follow Up

Where suitable, dental implants are praised as a method of providing fixed solutions with good longevity, and providing greatly improved retention for removable prostheses, resulting in increased levels of patient satisfaction and quality of life. However, with increasing evidence of long-term follow-up, there is a growing recognition of the susceptibility of dental implants to peri-implant diseases; peri-mucositis and peri-implantitis. This paper discusses the features of peri-implant disease and important aspects of assessment criteria. CPD/Clinical Relevance: This paper highlights the importance of supportive maintenance care for patients with dental implants, as well as the features and assessment of peri-implant disease.

High-risk HPV testing in women with borderline and mild dyskaryosis: long-term follow-up data and clinical relevance

2001 ◽  
Vol 195 (3) ◽  
pp. 300-306 ◽  
Author(s):  
G. Denise Zielinski ◽  
Peter J. F. Snijders ◽  
Lawrence Rozendaal ◽  
Feja J. Voorhorst ◽  
Arnold P. Runsink ◽  
...  
Keyword(s):  
High Risk ◽  
Clinical Relevance ◽  
Hpv Testing ◽  
Long Term Follow Up ◽  
High Risk Hpv

Direct Resin Composite Restorations in Vital Versus Root-filled Posterior Teeth: A Controlled Comparative Long-term Follow-up

2007 ◽  
Vol 32 (5) ◽  
pp. 437-442 ◽  
Author(s):  
G. Adolphi ◽  
M. Zehnder ◽  
L. M. Bachmann ◽  
T. N. Göhring
Keyword(s):  
Clinical Relevance ◽  
Resin Composite ◽  
Posterior Teeth ◽  
Composite Restorations ◽  
Long Term Follow Up

Clinical Relevance In endodontically-treated posterior teeth, minimal direct composite restorations had a tendency to fail more often than their counterparts in vital teeth.

The prevalence of short PR interval in adolescent athletes and non-athletes

2021 ◽  
Vol 28 (Supplement_1) ◽  
Author(s):  
M Abela ◽  
N Grech ◽  
S Degiorgio ◽  
R Xuereb ◽  
S Xuereb ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Screening Program ◽  
Adolescent Athletes ◽  
Funding Sources ◽  
Athletic Ability ◽  
Pr Interval ◽  
Long Term Follow Up ◽  
Heart Foundation

Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main funding source(s): Malta Heart Foundation and Beating Hearts Background Little is known about the prevalence and clinical relevance of an isolated short PR interval in young individuals. Objectives To explore the PR interval in adolescent athletes and non-athletes and determine possible association with sex, age, ethnicity, athletic ability and sporting discipline. Methods Between 2017-2018, school children aged 14-17 years were invited to participate in a National cardiac screening programme comprised of a health questionnaire and a resting 12-lead ECG. An athlete was defined as an individual participating in &gt;4 hours/week of organised sports. Sport disciplines were categorised as skill, power, mixed and endurance. A short PR interval was defined as &lt;120ms. Results A total of 1619 (61.0%) non-athletes and 1036 (39.0%) athletes  (median age 15 years, 50.5% females, 93.0% Caucasian) participated in the screening program. Most athletes participated in mixed sports (62.2%). The mean PR interval was shorter in non-athletes compared to athletes (136.65 ± 19.00ms vs 139.93 ± 19.86ms p &lt; 0.001) and in females compared to males (135.98 ± 18.39ms vs 139.93 ± 20.20ms, p &lt; 0.001). An isolated short PR interval was present in 405 (15.3%) individuals. Associated pre-excitation was present in an additional 5 cases (0.2%). A short PR interval was commoner in females (18.7% vs 11.7%, p &lt; 0.001) and in non-athletes (16.6% vs 13.2%, p = 0.020). Age (p = 0.657) and ethnicity (p = 0.115) did not influence the presence of a short PR interval. The presence of a short PR interval in adolescent athletes was independent of the sporting discipline category (p = 0.071), in both males (p = 0.400) and females (p = 0.233).  The absolute PR interval did not differ significantly between sporting categories (p = 0.065),  in both genders (males, p = 0.202, females, p = 0.279). Symptoms that were suggestive of arrhythmias were present in similar proportions of individuals with short and normal PR intervals (18.8% vs 17.1%, p = 0.393).  Conclusion An isolated short PR interval was a frequent finding in this cohort, with a predilection for females and non-athletes. The high frequency of short PR in young individuals suggests that in the absence of pre-excitation or symptoms, further evaluation is not warranted. Long-term follow-up studies may further elucidate the clinical relevance of this phenomenon.

Clinical Relevance of Neovascularisation on Duplex Ultrasound in the Long-Term Follow-up After Varicose Vein Operation

1999 ◽  
Vol 14 (3) ◽  
pp. 118 ◽  
Author(s):  
M. G. De Maeseneer ◽  
I. F. Tielliu ◽  
P. E. Van Schil ◽  
S. G. De Hert ◽  
E. J. Eyskens
Keyword(s):  
Varicose Vein ◽  
Clinical Relevance ◽  
Duplex Ultrasound ◽  
Varicose Vein Operation ◽  
Long Term Follow Up

Therapy and prevention for mental health: What if mental diseases are mostly not brain disorders?

2019 ◽  
Vol 42 ◽  
Author(s):  
John P. A. Ioannidis
Keyword(s):  
Mental Health ◽  
Mental Disease ◽  
Brain Disorders ◽  
Social Stressors ◽  
Labor Education ◽  
Mental Diseases ◽  
Long Term Follow Up ◽  
Political Decisions

AbstractNeurobiology-based interventions for mental diseases and searches for useful biomarkers of treatment response have largely failed. Clinical trials should assess interventions related to environmental and social stressors, with long-term follow-up; social rather than biological endpoints; personalized outcomes; and suitable cluster, adaptive, and n-of-1 designs. Labor, education, financial, and other social/political decisions should be evaluated for their impacts on mental disease.

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