Term twin pregnancy with hydatidiform mole and a normal fetus

1999 ◽  
Vol 262 (3-4) ◽  
pp. 189-191 ◽  
Author(s):  
Monica Abbi ◽  
Alka Kriplani ◽  
R. Uppal ◽  
D. Takkar
2014 ◽  
Vol 77 (2) ◽  
pp. 127-133 ◽  
Author(s):  
María Luisa Sánchez-Ferrer ◽  
Florentina Hernández-Martínez ◽  
Francisco Machado-Linde ◽  
Belén Ferri ◽  
Pablo Carbonel ◽  
...  

Author(s):  
Catarina J. Nascimento ◽  
Mariana Veiga ◽  
Ana Rita Silva ◽  
Joana Cominho

A coexistent molar pregnancy with a normal fetus is rare, with an incidence of 1 in 22.000 to 100.000 pregnancies-only 200 cases reported in the last two decades. The ultrasound is essential for an earlier diagnosis, and the management of these cases is challenging due to the increased risk of obstetrics complications and the possibility of posterior gestational trophoblastic neoplasia. Here we describe a 33-year-old healthy woman with a first-trimester twin pregnancy, presented with a normal fetus and a heterogeneous and vacuolar structure suggestive of complete hydatidiform mole. The pregnancy was interrupted, and a histological diagnosis confirmed complete hydatidiform mole in dichorionic/diamniotic twin pregnancy at 14 weeks. Molar twin pregnancy is a rare condition, and do not exist any consensus protocol to guide the clinical approach, so the decision to continue the pregnancy depends on the couple’s desire and maternal and fetal complications.


2006 ◽  
Vol 28 (4) ◽  
pp. 561-562
Author(s):  
P. Kretowicz ◽  
M. Samsel ◽  
M. Binkowska ◽  
R. Debski

Open Medicine ◽  
2019 ◽  
Vol 14 (1) ◽  
pp. 843-846
Author(s):  
Chengying Zeng ◽  
Yanbi Chen ◽  
Lijuan Zhao ◽  
Bo Wan

AbstractTwin pregnancy of a hydatidiform mole with a coexistent live fetus is very rare, and complete molar pregnancy is involved in most cases. A partial molar pregnancy almost always ends in miscarriage due to a triploid fetus. Here, we report a case of a 32-year-old Chinese woman with ultrasound diagnosis of a partial molar pregnancy. Amniocentesis suggested mosaicism, but the fetus was morphologically normal. The woman chose to continue the pregnancy after fully understanding the risk. The infant was delivered prematurely, and the presence of a large single placenta with molar changes. The baby’s peripheral blood chromosomes were diploid, and the pregnant woman had no serious complications. The diagnosis, management, and monitoring of this condition will remain challenging because of its rarity. Partial hydatidiform mole combined with pregnancy can result in delivering of a normal fetus and live birth under proper management.


2013 ◽  
Vol 33 (3) ◽  
pp. 194-200 ◽  
Author(s):  
María Luisa Sánchez-Ferrer ◽  
Francisco Machado-Linde ◽  
Alicia Martínez-Espejo Cerezo ◽  
Carolina Peñalver Parres ◽  
Belén Ferri ◽  
...  

2005 ◽  
Vol 29 (3) ◽  
pp. 415-417 ◽  
Author(s):  
Te-Chang Wu ◽  
Shu-Huei Shen ◽  
Sheng-Ping Chang ◽  
Cheng-Yen Chang ◽  
Wan-Yuo Guo

2019 ◽  
Vol 2019 ◽  
pp. 1-6
Author(s):  
Rishi Raj ◽  
Edilfavia Mae Uy ◽  
Matthew Hager ◽  
Kamyar Asadipooya

Context. Gestational trophoblastic disease (GTD) is a rare complication of pregnancy, ranging from molar pregnancy to choriocarcinoma. Twin pregnancies with GTD and coexisting normal fetus are extremely rare with an estimated incidence of 1 case per 22,000–100,000 pregnancies. Molecular mimicry between human chorionic gonadotrophin (hCG) and thyroid-stimulating hormone (TSH) leads to gestational trophoblastic hyperthyroidism (GTH) which is further associated with increased maternal and fetal complications. This is the first reported case in literature describing the delivery of a baby with biochemical euthyroid status following a twin pregnancy with hydatidiform mole (HM) associated with gestational trophoblastic hyperthyroidism (GTH). Case Description. A 24-year-old G4 P3 Caucasian female with twin gestation was admitted to hospital for gestation trophoblastic hyperthyroidism. She was later diagnosed to have twin pregnancy with complete mole and coexisting normal fetus complicated by gestational trophoblastic hyperthyroidism (GTH). Despite the risk associated with the continuation of molar pregnancy, per patient request, pregnancy was continued till viability of the fetus. The patient underwent cesarean section due to worsening preeclampsia and delivered a euthyroid baby at the 24th week of gestation. Conclusions. Twin pregnancy with gestational trophoblastic disease and coexisting normal fetus is associated with high risk of hyperthyroidism, and careful monitoring of the thyroid function test along with dose titration of thionamides is of utmost importance throughout the gestation. If normal thyroid hormone levels are maintained during the pregnancy, euthyroidism could be successfully achieved in the baby.


2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Colin Johnson ◽  
Caroline Davitt ◽  
Rachel Harrison ◽  
Meredith Cruz

Twin pregnancies complicated by complete hydatidiform mole coexisting with a viable fetus are rare and may result in significant complications. We describe the expectant management and our surgical approach in a 27-year-old Rh-negative woman presenting with recurrent episodes of vaginal bleeding and a twin pregnancy consisting of a molar pregnancy coexisting with a normal fetus. Inpatient management was undertaken with close maternal and fetal monitoring until cesarean delivery of a healthy female infant and histopathologically confirmed complete hydatidiform molar pregnancy (karyotype 46XX) at 34 weeks with no evidence of malignancy.


2006 ◽  
Vol 26 (4) ◽  
pp. 379-380 ◽  
Author(s):  
M. Ingec ◽  
B. Borekci ◽  
S. Altas ◽  
S. Kadanali

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