What is optimal timing of warming for transferring vitrified cleavage stage of day 3 slow-growing embryos? A cohort retrospective study

2021 ◽  
Author(s):  
Lan Geng ◽  
Jia-hui Wu ◽  
Jia-qi Luo ◽  
Rang Liu ◽  
Jun-sheng Li ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Optimal Timing ◽  
Cleavage Stage ◽  
Slow Growing

scholarly journals What Is the Optimal Timing of Thawing for Transferring Vitrified-warmed Cleavage Stage of Slow-growing Embryos? A Cohort Retrospective Study

2021 ◽  
Author(s):  
Lan Geng ◽  
Jia-hui Wu ◽  
Jia-qi Luo ◽  
Yu Shi ◽  
Wei-ping Qian ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Retrospective Cohort ◽  
Pregnancy Loss ◽  
Clinical Pregnancy ◽  
Frozen Embryo Transfer ◽  
Optimal Timing ◽  
Cleavage Stage ◽  
Significant Difference ◽  
Slow Growing ◽  
Day 3 Embryos

Abstract PurposeTo evaluate optimal thawing time, the early thawing or the routine thawing time, for transferring vitrified-warmed, and cultured overnight cleavage stage of the slow-growing embryos on Day 3 in frozen embryo transfer (FET) cycle. MethodsThis was a retrospective cohort study from January 2017 to July 2018, a total of 705 slow-growing embryos FET cycles in which the patients were aged <40. Thawing cleavage stage slow-growing Day 3 embryos on either the 2nd or 3rd day after ovulation in natural cycle or the equivalent timing of the artificial cycles. ResultsFor slow growing embryos, the clinical pregnancy rate of early thawing group (152/468 (32.5%)) was significantly higher than that of routine thawing group (55/235 (23.4%)) (OR 1.39(CI 1.06-1.81), p=0.01), while there was no statistically significant difference in pregnancy loss in early thawing group (39/170 (22.9%)) versus in routine thawing group (16/62 (25.8%)) (OR 0.89 (CI 0.53-1.47), p =0.65). ConclusionFor slow-growing embryos, higher pregnancy outcomes were shown in early thawing strategy as compared to the routine thawing, which suggested that the improvement of endometrium-embryo synchronism may correct the time difference brought by the slow-growing embryos.

scholarly journals What is the optimal timing of thawing for transferring vitrified-warmed cleavage stage of slow-growing embryos? A cohort retrospective study

2020 ◽  
Author(s):  
Lan Geng ◽  
Jia-hui Wu ◽  
Jia-qi Luo ◽  
Yu Shi ◽  
Wei-ping Qian ◽  
...  
Keyword(s):  
Pregnancy Outcomes ◽  
Retrospective Cohort ◽  
Pregnancy Loss ◽  
Clinical Pregnancy ◽  
Frozen Embryo Transfer ◽  
Optimal Timing ◽  
Cleavage Stage ◽  
Significant Difference ◽  
Slow Growing ◽  
Day 3 Embryos

Abstract Background To evaluate optimal thawing time, the early thawing or the routine thawing time, for transferring vitrified-warmed, and cultured overnight cleavage stage of the slow-growing embryos on Day 3 in frozen embryo transfer (FET) cycle. Methods This was a retrospective cohort study from January 2017 to July 2018, a total of 705 slow-growing embryos FET cycles in which the patients were aged < 40. Thawing cleavage stage slow-growing Day 3 embryos on either the 2nd or 3rd day after ovulation in natural cycle or the equivalent timing of the artificial cycles. Results For slow growing embryos, the clinical pregnancy rate of early thawing group (152/468 (32.5%)) was significantly higher than that of routine thawing group (55/235 (23.4%)) (OR 1.39(CI 1.06–1.81), p = 0.01), while there was no statistically significant difference in pregnancy loss in early thawing group (39/170 (22.9%)) versus in routine thawing group (16/62 (25.8%)) (OR 0.89 (CI 0.53–1.47), p = 0.65). Conclusion For slow-growing embryos, higher pregnancy outcomes were shown in early thawing strategy as compared to the routine thawing, which suggested that the improvement of endometrium-embryo synchronism may correct the time difference brought by the slow-growing embryos.

Challenges in Antenatal Corticosteroid Prescribing: A Retrospective Study

2020 ◽  
Vol 16 (4) ◽  
pp. 327-333
Author(s):  
Shannon Armstrong-Kempter ◽  
Lucinda Beech ◽  
Sarah J. Melov ◽  
Adrienne Kirby ◽  
Roshini Nayyar
Keyword(s):  
Retrospective Study ◽  
Obstetric Care ◽  
Patient Characteristics ◽  
Tertiary Hospital ◽  
Optimal Timing ◽  
Prescribing Practices ◽  
Antenatal Corticosteroids ◽  
Term Infants ◽  
Preterm Premature Rupture ◽  
To Receive

Background: The discovery of the benefits of antenatal corticosteroids (ACS) for preterm infants was one of the most significant developments in obstetric care. However, due to the difficulty in predicting preterm delivery, optimal use of ACS, is challenging. Objective: To describe prescribing practices for antenatal corticosteroids (ACS) at a tertiary hospital over five years to determine whether ACS were received at optimal timing; to determine patient characteristics of women receiving ACS at optimal timing; to determine patient characteristics of those who did not receive ACS as indicated and to examine the trend in ACS prescribing over the study period. Methods: We performed a retrospective study of all deliveries from January 2011 to December 2015. The rates of ACS prescription for each group of women (preterm, late preterm, and term) were recorded and analysed. Results: A total of 65% of women who delivered before 34 weeks’ gestation received ACS. Of these women, 63% delivered within 7 days of receiving ACS. Women most likely to receive ACS with optimal timing were primiparous (relative risk [RR], 1.25 [CI, 1.08-1.45]), or women diagnosed with pre-eclampsia (RR, 1.34 [CI 1.10-1.63]), preterm premature rupture of membranes (RR, 1.33 [CI, 1.15-1.54]) or threatened preterm labour (RR, 1.42 [CI, 1.22-1.65]). Conclusion: A significant number of women and babies are exposed to ACS without commensurate benefit, and a significant number who deliver preterm do not receive ACS. The percentage of preterm and term infants receiving ACS should be determined to optimise service delivery.

What is the optimal timing of embryo transfer when there are only one or two embryos at cleavage stage?

2019 ◽  
Vol 35 (8) ◽  
pp. 665-668 ◽  
Author(s):  
Jigal Haas ◽  
Jim Meriano ◽  
Rawad Bassil ◽  
Eran Barzilay ◽  
Robert F Casper
Keyword(s):  
Embryo Transfer ◽  
Optimal Timing ◽  
Cleavage Stage

Optimal timing of laparoscopic cholecystectomy after gallbladder drainage for acute cholecystitis: A multi‐institutional retrospective study

2020 ◽  
Vol 27 (8) ◽  
pp. 451-460
Author(s):  
Yoshito Tomimaru ◽  
Nariaki Fukuchi ◽  
Shigekazu Yokoyama ◽  
Takuji Mori ◽  
Masahiro Tanemura ◽  
...  
Keyword(s):  
Laparoscopic Cholecystectomy ◽  
Retrospective Study ◽  
Acute Cholecystitis ◽  
Optimal Timing ◽  
Gallbladder Drainage

Blastocyst versus cleavage-stage elective single embryo transfer - a comparative retrospective study

2015 ◽  
Vol 104 (3) ◽  
pp. e181-e182
Author(s):  
Z. Veleva ◽  
S. Boulet ◽  
S. Makinen ◽  
H. Martikainen ◽  
A. Tiitinen ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Embryo Transfer ◽  
Single Embryo Transfer ◽  
Cleavage Stage ◽  
Elective Single Embryo Transfer

What is the optimal timing of embryo transfer when there are only up to two embryos at cleavage stage?

2017 ◽  
Vol 108 (3) ◽  
pp. e334
Author(s):  
J. Haas ◽  
J.S. Meriano ◽  
R. Bassil ◽  
R. Casper
Keyword(s):  
Embryo Transfer ◽  
Optimal Timing ◽  
Cleavage Stage

scholarly journals Post-warming survival rates and clinical outcomes of human cleavage stage embryos vitrified/warmed using CryoTouch and Cryotop methods

2021 ◽  
Vol 26 (1) ◽  
Author(s):  
Somayeh Keshavarzi ◽  
Azadeh Dokht Eftekhari ◽  
Hajar Vahabzadeh ◽  
Marzieh Mehrafza ◽  
Robabeh Taheripanah ◽  
...  
Keyword(s):  
Retrospective Study ◽  
Survival Rate ◽  
Clinical Outcomes ◽  
Live Birth ◽  
Survival Rates ◽  
Implantation Rate ◽  
Clinical Pregnancy ◽  
Human Embryos ◽  
Cleavage Stage ◽  
Embryo Survival

Abstract Background Vitrification has become the method of choice for cryopreservation of human embryos and gametes. There are multiple commercial media, containing different combinations and concentrations of cryoprotectants, available for vitrification and warming procedures. The aim of this retrospective study was to compare post-warming survival rate and clinical outcomes of cleavage stage embryos vitrified/warmed using two different commercial methods (CryoTouch and Cryotop) during intracytoplasmic sperm injection/frozen embryo transfer (ICSI/FET) cycles. This retrospective study evaluated a total of 173 FET cycles performed on 446 warmed cleavage stage embryos between January 2018 and December 2020. Post-warming embryo survival rate and clinical outcomes including clinical pregnancy, implantation, and live birth rates were calculated. Results The results showed no significant differences between two groups in terms of post-warming survival rate (p value = 0.5020), clinical pregnancy rate (p value = 0.7411), implantation rate (p value = 0.4694), and live birth rate (p value = 0.5737). Conclusions Collectively, high successful rates were observed in outcomes of vitrified/warmed cleavage stage embryos using both CryoTouch and Cryotop commercial methods.

scholarly journals Visualization of pleural fissures in infants on computed tomography

2019 ◽  
Vol 2 (1) ◽  
pp. e000034
Author(s):  
Andrew Phelps ◽  
Cynthia Tan ◽  
Saveen Ahuja ◽  
Dean Kolnick ◽  
Jesse Courtier ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Retrospective Study ◽  
Age Groups ◽  
Chest Ct ◽  
Institutional Review Board ◽  
Optimal Timing ◽  
Age Group ◽  
Lung Lesions ◽  
Institutional Review ◽  
Preoperative Ct

PurposeFor infants with prenatally detected lung lesions, a chest CT is performed prior to surgery. The chest CT is performed as close to the surgery date as possible, because it is presumed that the visualization of lung fissures would be poor in the immediate neonatal setting. However, this presumption has never been formally studied. The purpose of this study is to assess differences in lung fissure visualization on chest CT in different infant age groups.MethodsThis was a retrospective study of clinically indicated chest CT approved by the institutional review board performed in infants of different ages. The visibility of pleural fissures was subjectively assessed by three pediatric radiologists who were blinded to age group.ResultsIn the 0–2 months age group, 80% of all fissure segments were visible versus 92% in the 5–6 months group (p=0.04) and 95% in the 7–9 months group (p=0.01).ConclusionsThe ability to visualize pleural fissures on CT increases with infant age. This observation should be taken into consideration when choosing the optimal timing of preoperative CT for asymptomatic congenital lung lesions.

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