scholarly journals Analysis of severe psychological stressors in women during fertility treatment: Japan-Female Employment and Mental health in Assisted reproductive technology (J-FEMA) study

2021 ◽  
Author(s):  
Yuko Ikemoto ◽  
Keiji Kuroda ◽  
Motoki Endo ◽  
Atsushi Tanaka ◽  
Rikikazu Sugiyama ◽  
...  
Keyword(s):  
Mental Health ◽  
Assisted Reproductive Technology ◽  
Reproductive Technology ◽  
Female Employment ◽  
Fertility Treatment ◽  
Psychological Stressors

scholarly journals Risk factors for resignation from work after starting infertility treatment among Japanese women: Japan-Female Employment and Mental health in Assisted reproductive technology (J-FEMA) study

2020 ◽  
pp. oemed-2020-106745
Author(s):  
Yuya Imai ◽  
Motoki Endo ◽  
Keiji Kuroda ◽  
Kiyohide Tomooka ◽  
Yuko Ikemoto ◽  
...  
Keyword(s):  
Mental Health ◽  
Risk Factors ◽  
Assisted Reproductive Technology ◽  
Educational Background ◽  
Infertility Treatment ◽  
Reproductive Technology ◽  
Japanese Women ◽  
Female Employment ◽  
Technology Study ◽  
Psychological Burden

ObjectiveTo elucidate the risk factors associated with resignation from work of Japanese women undergoing infertility treatment.MethodsA total of 1727 female patients who attended a private fertility clinic in Japan participated in the Japan-Female Employment and Mental health in Assisted reproductive technology study. Questions related to demographic, clinical and socioeconomic characteristics were employed in the questionnaire. Out of the 1727 patients, 1075 patients who were working at the time of initiating infertility treatment and felt infertility treatment incompatible with work were included in the analysis. Risk factors for resignation were assessed by using multivariable logistic regression models.ResultsAmong 1075 working women who started infertility treatment, 179 (16.7%) subsequently resigned. Multivariable-adjusted ORs for resignation in those with lower educational background and infertility for ≥2 years were 1.58 (95% CI: 1.07 to 2.34) and 1.82 (95% CI: 1.15 to 2.89), respectively. The OR for resignation in non-permanent workers undergoing infertility treatment was 2.65 (95% CI: 1.61 to 4.37). While experiencing harassment in the workplace approached significance, lack of support from the company was significantly associated with resignation after starting infertility treatment, with ORs of 1.71 (95% CI: 0.98 to 2.99) and 1.91 (95% CI: 1.28 to 2.86), respectively.ConclusionOne-sixth of women resigned after starting infertility treatments. It was found that factors related to education, infertility duration and work environment were significantly associated with resignation. Reducing the physical and psychological burden endured by women, for example, by increasing employer-provided support, is vitally important in balancing infertility treatment with maintenance of work life.

Estimation of the Contribution of Assisted and Non-Assisted Reproductive Technology Fertility Treatments to Multiple Births During the Past 30 Years in Japan: 1979–2008

2011 ◽  
Vol 14 (5) ◽  
pp. 476-483 ◽  
Author(s):  
Syuichi Ooki
Keyword(s):  
Assisted Reproductive Technology ◽  
Social Impact ◽  
Vital Statistics ◽  
Reproductive Technology ◽  
Multiple Births ◽  
Fertility Treatment ◽  
Approximation Formula ◽  
Multiple Birth ◽  
Fertility Treatments ◽  
Ovulation Stimulation

The effect of assisted reproductive technology (ART) and non-ART ovulation stimulation fertility treatment on the number and rate of multiple live births from 1979–2008 in Japan was estimated using two independent data sources, ART statistics and vital statistics. Japanese ART statistics presented by the Japan Society of Obstetrics and Gynecology between 1989 and 2008 were gathered and reanalyzed. The number and rates of ART between 1984 and 1988 were interpolated using an approximation formula, using the values from 1983, when the first ART baby was born in Japan, and the 1989–1992 values. The number of ART multiples between 1979–1982 was set as equal to zero. The minimum (or maximum) number of non-ART iatrogenic multiple births was estimated by subtracting the maximum (or minimum) ART multiples from the total iatrogenic multiples, which was estimated by vital statistics assuming that spontaneous multiple-birth rates according to maternal age class would be constant. There was an overall increase in the non-ART multiple births during the 30-year period, whereas ART multiples tended to increase from 1983 to 2005, and then rapidly decreased thereafter. The number or percentage of ART multiples was almost consistently lower than that of non-ART multiples. The percentage of non-ART multiples (33%) among the total multiples was estimated to be about three times more than the ART multiples (11–12%) in 2008. Given the medical and social impact of multiple births, it is imperative to construct a hospital-based monitoring system for fertility treatments, specially non-ART fertility treatments and multiple births.

scholarly journals Changes in Mental Health of Women Undergoing Assisted Reproductive Technology Treatment During the COVID-19 Pandemic Outbreak in Xi'an, China

2021 ◽  
Vol 9 ◽  
Author(s):  
Pengfei Qu ◽  
Doudou Zhao ◽  
Peng Jia ◽  
Shaonong Dang ◽  
Wenhao Shi ◽  
...  
Keyword(s):  
Mental Health ◽  
Assisted Reproductive Technology ◽  
Control Period ◽  
Cross Sectional Study ◽  
Reproductive Technology ◽  
The Novel ◽  
Cross Sectional ◽  
Outbreak Period ◽  
Global Pandemic ◽  
Novel Coronavirus

Objective: To investigate the mental health of women undergoing assisted reproductive technology (ART) treatment during the novel coronavirus pneumonia (COVID-19) pandemic outbreak in Xi'an, China.Methods: A repeated cross-sectional study was administered to women undergoing ART treatment during the outbreak period (599 women in February 2020) and the control period (892 women in May 2020) at the Northwest Women's and Children's Hospital, Xi'an, China.Results: Both the ART-treated women surveyed during the outbreak period and those surveyed during the control period had high scores on the fear dimension (0.88, 0.51). The total scores for mental health among the participants during the control period were lower than those during the outbreak period (difference = −0.22; 95% CI = −0.25, −0.18). Lower scores were also seen during the control period, compared to those in the outbreak period, for depression (difference = −0.18; 95% CI = −0.23, −0.13), neurasthenia (difference = −0.31; 95% CI = −0.36, −0.25), fear (difference = −0.37; 95% CI = −0.43, −0.31), compulsion anxiety (difference = −0.13; 95% CI = −0.16, −0.09), and hypochondriasis (difference = −0.09; 95% CI = −0.12, −0.06).Conclusions: During the COVID-19 global pandemic, the mental health of women undergoing ART treatment in Xi'an, China, was primarily manifested as fear. As the pandemic was brought under control, the mental health of ART-treated women improved. As evidenced by these results, the COVID-19 pandemic influences the mental health of women undergoing ART treatment, and clinicians should be aware of this for similar future situations.

scholarly journals Congenital malformations and minor anomalies in newborns depending on the type of resolved infertility and health of the parents

2021 ◽  
pp. 22-28
Author(s):  
M. K. Soboleva ◽  
D. A. Кinsht
Keyword(s):  
Assisted Reproductive Technology ◽  
Congenital Malformations ◽  
Medical Center ◽  
Reproductive Technologies ◽  
Reproductive Technology ◽  
Blastocyst Stage ◽  
Fertility Treatment ◽  
Complete Continuity ◽  
History Of ◽  
Minor Anomalies

Introduction. The use of  sisted reproductive technologies has had sufficient experience to reduce the risks associated with the technologies themselves. But pediatricians remain concerned about the health of children born from induced pregnancies because of the influence of the parents’ initial health on perinatal outcomes. Congenital malformations remain socially significant, the risk of which may be higher for children from induced pregnancy.Objective: to evaluate the effect of initial parental health and the methods of assisted reproductive technology used on the formation of congenital malformations and minor anomalies in children from singleton induced pregnancies.Materials and Methods. A retrospective cohort study was conducted using data on live-born children from singleton induced pregnancy born at the Avicenna Medical Center (Novosibirsk) over the period from 2007 to 2017 (n = 409). The reproductive, somatic, and infectious history of the parents and the methods of assisted reproductive technology used were assessed. Parental fertility treatment up to childbirth was performed in the same center, which ensured complete continuity of follow-up. Differences between the groups of children from SIP with and without congenital anomalies were determined using Pearson’s chi-squared test.Results and discussion. We found that children with congenital malformations and minor anomalies were more often born as a result of subsequent pregnancies; thawed embryos transferred at the blastocyst stage were used in assisted reproductive technology programs (p < 0.05); exacerbations of herpes type 2 infection were diagnosed during the current pregnancy (p < 0.05). In the group of children with only CM, the parents had a longer history of infertility (8.3 ± 1.2) years; pregnancy was achieved by transferring fresh embryos at the blastocyst stage (in 68.2% of cases). In the group of children without congenital malformations and minor anomalies, the maternal infectious history was more severe: there were significantly more frequent cases of urogenital infections (p < 0.05) and exacerbations of herpes simplex virus type 1 during pregnancy (p < 0.05).Conclusion. A set of measures aimed at an earlier solution of the infertility problem is necessary for the primary prevention of congenital abnormalities associated with the age and duration of parental infertility.

scholarly journals Fertility Scoring Index: Cimar's Novel System to Predict assisted Reproductive Technology Success

2014 ◽  
Vol 5 (2) ◽  
pp. 44-57
Author(s):  
Rochelle Heroina Gracias ◽  
Louis Fessy Thalakottoor ◽  
Parasuram Gopinath ◽  
Gopinathan Kannoly Karunakaran
Keyword(s):  
Success Rate ◽  
Assisted Reproductive Technology ◽  
Pregnancy Outcome ◽  
Infertility Treatment ◽  
Reproductive Technology ◽  
Fertility Treatment ◽  
Successful Outcome ◽  
List Type ◽  
Several Variables ◽  
Scoring Index

ABSTRACT Background About 15% of all couples are infertile and require fertility treatment. With constantly improving clinical and laboratory procedures, pregnancy rates of about 30% per transfer are routinely reported. In non-donor-oocyte cycles, the percentage of in vitro fertilization/intracytoplasmic sperm injection (IVF/ ICSI) cycles that result in pregnancy ranges from 18 to 45%, depending on several factors (Society for Assisted Reproductive Technology 2009). But a patients concern is about the success rate—‘What is my chance of getting pregnant’? For the success in IVF/ICSI—embryo transfer cycle there are many variables thought to be directly related to the implantation and successful outcome. Aims and objectives To identify independent predictors ICSI outcome. To make a composite predictive scoring system— For patient selection and counseling for assisted reproductive technology (ART). That may prove critical in counseling poor prognosis patients, about their prognosis or against IVF treatment (e.g. patients with least benefits in undergoing IVF can opt for donor oocytes/surrogacy, etc. without wasting a cycle in trial and error). Optimizing treatment by developing more customized individually tailored treatment plan with consideration to predictive factors. Study design The research was approved by the institutional review board. A retrospective ongoing study was performed, over a period of 3 years at a well established infertility institution. A sample size of 1020 patients was considered from two hospitals of the same institution. The patients were stimulated by different protocols specific to each patients age, AFC, etc [Polycystic ovarian syndrome (PCOS) patients showing hyperresponse in follicular study-antagonist protocol]; though a majority underwent long agonist protocol. They were evaluated and the outcome was assessed through logistic regression analysis. Several variables were taken into consideration—to name a few; age, previous pregnancy outcome, previous ART treatment if any, E2/LH/P4 [baseline values and on the day of human chorionic gonadotropin (hCG)], etc. A preferential scoring was derived to obtain a predictive scoring for pregnancy outcome. Results A pregnancy predicting scoring was arrived at. On considering several variables, the cut off score represented a 50% success rate of IVF/ICSI cycle. Conclusion Bearing in mind that fertility is independent of hospital protocols and primarily dependent on the individual woman, the derived predictive scoring can be applied to individual cohort of patients under infertility treatment and has excellent discrimination ability for assessing the likelihood of pregnancy outcome. Application of this scoring will allow individualized treatment decision-making for patients under infertility treatment. How to cite this article Gracias RH, Thalakottoor LF, Gopinath P, Karunakaran GK. Fertility Scoring Index: Cimar's Novel System to Predict Assisted Reproductive Technology Success. Int J Infertil Fetal Med 2014;5(2):44-57.

Influence of the awareness of COVID-19 pandemic on assisted reproductive technology clinic in Africa, South of the Sahara

2020 ◽  
Vol 11 (5) ◽  
Author(s):  
Bamgboye M Afolabi ◽  
Abayomi B Ajayi ◽  
Tola Ajayi ◽  
Victor D Ajayi ◽  
Ifeoluwa Oyetunji ◽  
...  
Keyword(s):  
Assisted Reproductive Technology ◽  
Genetic Diagnosis ◽  
Health And Safety ◽  
Face Mask ◽  
Reproductive Technology ◽  
Fertility Treatment ◽  
Left Behind ◽  
The World ◽  
The Government ◽  
Clinic Manager

Introduction: COVID-19 pandemic has taken the world by storm and consequently, various reproductive medicine societies had since issued guidelines based on best judgement for the safety of IVF patients and attending health staffs Objective: The objective of this study was to assess the opinions of IVF staff in sub-Sahara Africa on the awareness of COVID-19 on Assisted Reproductive Technology. The study also evaluated some of the measures that can mitigate the effects of the virus in IVF clinics. Methodology: Different cadres of staff at Nordica Fertility Center (NFC) in Lagos, Nigeria were interviewed. Those interviewed included the Medical Director, Clinicians/Gynecologists, Clinic Manager, Nurses, Embryologists, Counsellor, Business Developing Unit, Client Liaison Officers and Accounts Officer. Their responses were collated, and the key points were documented. Each staff in face mask was visited by one interviewer who observed all government-recommended sanitary precautions including wearing a facemask and maintaining social distance between her and the interviewee. Result: The response of the MD on the fate of IVF clinic in Africa within the next 6 months to 1 year of the Covid-19 pandemic was that the overall economy is a major determinant of the ability of clients to pay for IVF services. Infertile women would still want to have children but “how would they pay for the services?” since ART is not subsidized by the government but mostly paid as out-of-pocket expense in this part of the world. The main points were that IVF clinics are not immune to the economy and vaccine may or may not favor IVF, reasons being; The virus is about 5 months old hence still much to be discovered There is no solid evidence that the virus affects reproduction No evidence of mother-to-child transmission and The virus can survive in cold environment therefore, it could survive cryopreservation. The embryologist was of the opinion that IVF clinics in Africa need to understand the virus more to decide whether: Attend to COVID-19 patients or not and if so, how best to care for them Better prepare modalities of cryopreservation such as Appropriate equipment Batching gametes together with HIV or Hepatitis patients In same or separate equipment and Getting special cryo-tanks for Covid-19 patients. Embryologist agreed that clinics will be able to perform other adjunct fertility treatment such as Pre-implantation Genetic Diagnosis (PGD), dependent on clinics’ ability to have separate equipment for Covid19-positive and negative patients. Conclusion: Africa is not left behind in experiencing the effects of COVID-19 and ART, for which concerns for the survival of privately owned clinics to ensure and safeguard the health and safety of patients, staff and the unborn babies are expressed. As of now, no-one is sure of patients that are symptomatic and those not symptomatic, as testing in the country, just like in most parts of the world, are still inadequate. When a vaccine is available, it may be mandatory for every IVF patient to get a shot. The main points of other cadres of staff are discussed.

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