HLA-DM is expressed on the cell surface and colocalizes with HLA-DR and invariant chain in human Langerhans cell

1998 ◽  
Vol 290 (12) ◽  
pp. 674-680 ◽  
Author(s):  
Tove Andersson ◽  
Ardan Patwardhan ◽  
Axel Emilson ◽  
Kjell Carlsson ◽  
A. Scheynius
Keyword(s):  
Cell Surface ◽  
Langerhans Cell ◽  
Invariant Chain ◽  
Hla Dr

INTRACELLULAR AND CELL SURFACE MAPPING OF HLA DR IN THE PRESENCE AND ABSENCE OF THE INVARIANT CHAIN

1997 ◽  
Vol 25 (2) ◽  
pp. 259S-259S ◽  
Author(s):  
Kathy Triantafilou ◽  
Keith M. Wilson ◽  
Nelson Fernandez
Keyword(s):  
Cell Surface ◽  
Invariant Chain ◽  
Surface Mapping ◽  
Hla Dr ◽  
Presence And Absence

scholarly journals Cell surface HLA-DR-invariant chain complexes are targeted to endosomes by rapid internalization.

1993 ◽  
Vol 90 (18) ◽  
pp. 8581-8585 ◽  
Author(s):  
P. A. Roche ◽  
C. L. Teletski ◽  
E. Stang ◽  
O. Bakke ◽  
E. O. Long
Keyword(s):  
Cell Surface ◽  
Invariant Chain ◽  
Chain Complexes ◽  
Hla Dr

scholarly journals Flow Cytometric Analysis of T, B, and NK Cells Antigens in Patients with Mycosis Fungoides

2015 ◽  
Vol 2015 ◽  
pp. 1-8 ◽  
Author(s):  
Serkan Yazıcı ◽  
Emel Bülbül Başkan ◽  
Ferah Budak ◽  
Barbaros Oral ◽  
Şaduman Balaban Adim ◽  
...  
Keyword(s):  
Cell Surface ◽  
Mycosis Fungoides ◽  
Peripheral Blood ◽  
Prognostic Value ◽  
Flow Cytometric Analysis ◽  
Surface Antigens ◽  
Cell Surface Antigens ◽  
Flow Cytometric ◽  
Hla Dr ◽  
The Mean

We retrospectively analyzed the clinicopathological correlation and prognostic value of cell surface antigens expressed by peripheral blood mononuclear cells in patients with mycosis fungoides (MF). 121 consecutive MF patients were included in this study. All patients had peripheral blood flow cytometry as part of their first visit. TNMB and histopathological staging of the cases were retrospectively performed in accordance with International Society for Cutaneous Lymphomas/European Organization of Research and Treatment of Cancer (ISCL/EORTC) criteria at the time of flow cytometry sampling. To determine prognostic value of cell surface antigens, cases were divided into two groups as stable and progressive disease. 17 flow cytometric analyses of 17 parapsoriasis (PP) and 11 analyses of 11 benign erythrodermic patients were included as control groups. Fluorescent labeled monoclonal antibodies were used to detect cell surface antigens: T cells (CD3+, CD4+, CD8+, TCRαβ+, TCRγδ+, CD7+, CD4+CD7+, CD4+CD7−, and CD71+), B cells (HLA-DR+, CD19+, and HLA-DR+CD19+), NKT cells (CD3+CD16+CD56+), and NK cells (CD3−CD16+CD56+). The mean value of all cell surface antigens was not statistically significant between parapsoriasis and MF groups. Along with an increase in cases of MF stage statistically significant difference was found between the mean values of cell surface antigens. Flow cytometric analysis of peripheral blood cell surface antigens in patients with mycosis fungoides may contribute to predicting disease stage and progression.

Cell surface pattern of ICAM-1 and HLA-DR on epidermal basal cells of mycosis fungoides

1991 ◽  
Vol 2 (3) ◽  
pp. 227
Author(s):  
Shuhei Imayama ◽  
Yutaka Yashima ◽  
Minao Furumura ◽  
Yoshiaki Hori
Keyword(s):  
Cell Surface ◽  
Mycosis Fungoides ◽  
Surface Pattern ◽  
Basal Cells ◽  
Hla Dr

scholarly journals Direct demonstration of an HLA-DR allotypic determinant on the low molecular weight (beta) subunit using a mouse monoclonal antibody specific for DR3

1982 ◽  
Vol 156 (1) ◽  
pp. 104-111 ◽  
Author(s):  
JP Johnson ◽  
T Meo ◽  
G Reithmuller ◽  
DJ Schendel ◽  
R Wank
Keyword(s):  
Molecular Weight ◽  
Monoclonal Antibody ◽  
Cell Surface ◽  
B Cell ◽  
Beta Subunit ◽  
Low Molecular Weight ◽  
Β Subunit ◽  
Direct Demonstration ◽  
Hla Dr ◽  
Human B Cell

A murine monoclonal antibody directed against a human B cell surface antigen with the characteristics of HLA-DR is described. The antigen detected is tightly linked to HLA and is correlated with the alloantigen HLA-Dw/DR3. Reactivity with a fraction of Dw/DRw6 cells is also observed. The determinant recognized by this antibody has been shown to be present on the smaller molecular weight β subunit of the HLA-DR antigen.

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