Immunohistochemical and ultrastructural study of basophilic inclusions in adult-onset motor neuron disease

2001 ◽  
Vol 102 (2) ◽  
pp. 200-206 ◽  
Author(s):  
Shoichi Sasaki ◽  
Sono Toi ◽  
Akiko Shirata ◽  
Kiyomi Yamane ◽  
Hideo Sakuma ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Ultrastructural Study ◽  
Adult Onset

scholarly journals Erratum to: Immunohistochemical and ultrastructural study of basophilic inclusions in adult-onset motor neuron disease

2001 ◽  
Vol 103 (1) ◽  
pp. 88-88
Author(s):  
Shoichi Sasaki ◽  
Sono Toi ◽  
Akiko Shirata ◽  
Kiyomi Yamane ◽  
Hideo Sakuma ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Ultrastructural Study ◽  
Adult Onset

Topographic involvement of the striatal efferents in basal ganglia of patients with adult-onset motor neuron disease with basophilic inclusions

1995 ◽  
Vol 89 (6) ◽  
pp. 513-518 ◽  
Author(s):  
Hidefumi Ito ◽  
Hirofumi Kusaka ◽  
Sadayuki Matsumoto ◽  
Terukuni Imai
Keyword(s):  
Basal Ganglia ◽  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Adult Onset

scholarly journals Sporadic lower motor neuron disease with adult onset: classification of subtypes

Brain ◽  
2003 ◽  
Vol 126 (5) ◽  
pp. 1036-1047 ◽  
Author(s):  
R. M. Van den Berg-Vos ◽  
J. Visser ◽  
H. Franssen ◽  
M. de Visser ◽  
J. M. B. V. de Jong ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Lower Motor Neuron ◽  
Adult Onset ◽  
Lower Motor Neuron Disease

Immunohistochemical identification of messenger RNA-related proteins in basophilic inclusions of adult-onset atypical motor neuron disease

2008 ◽  
Vol 116 (4) ◽  
pp. 439-445 ◽  
Author(s):  
Kengo Fujita ◽  
Hidefumi Ito ◽  
Satoshi Nakano ◽  
Yoshimi Kinoshita ◽  
Reika Wate ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Messenger Rna ◽  
Adult Onset ◽  
Related Proteins ◽  
Immunohistochemical Identification

scholarly journals ALS-linked TDP-43 mutations produce aberrant RNA splicing and adult-onset motor neuron disease without aggregation or loss of nuclear TDP-43

2013 ◽  
Vol 110 (8) ◽  
pp. E736-E745 ◽  
Author(s):  
E. S. Arnold ◽  
S.-C. Ling ◽  
S. C. Huelga ◽  
C. Lagier-Tourenne ◽  
M. Polymenidou ◽  
...  
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Rna Splicing ◽  
Adult Onset ◽  
Aberrant Rna

Motor Neuron Disease: A Disease of Old Age

1993 ◽  
Vol 38 (6) ◽  
pp. 178-182 ◽  
Author(s):  
A.M. Chancellor ◽  
A Hendry ◽  
F. I. Caird ◽  
C.P. Warlow ◽  
A.I. Weir
Keyword(s):  
Motor Neuron ◽  
Motor Neuron Disease ◽  
Elderly Women ◽  
The Elderly ◽  
Population Based ◽  
Adult Onset ◽  
Population Based Study ◽  
Medical Unit ◽  
Negative Prognostic Factor ◽  
Epidemiological Trends

There is little information dealing specifically with motor neuron disease (MND) in the elderly. Given current epidemiological trends, geriatricians will be increasingly called upon to diagnose and manage this condition. We report four patients who presented within a six month period to a geriatric medical unit, and place this experience in the perspective of 229 patients from a population-based study of adult-onset MND in Scotland in 1989 and 1990. In 1990 Scotland had a crude annual incidence of MND of 2.25/100,000; the figure for those over 65 is four times greater. MND is more common in men, but the sex ratio was nearly equal over the age of 65. The risk of presenting with bulbar palsy was greater in women, and even higher in elderly women. This, together with increasing age, is the most important negative prognostic factor in MND. Problems with the diagnosis and management of MND in the elderly are highlighted.

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