Expression of connexin 43 and connexin 32 gap-junction proteins in epilepsy-associated brain tumors and in the perilesional epileptic cortex

2001 ◽  
Vol 101 (5) ◽  
pp. 449-459 ◽  
Author(s):  
Eleonora Aronica ◽  
Jan A. Gorter ◽  
Gerard H. Jansen ◽  
Sieger Leenstra ◽  
Bulent Yankaya ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Gap Junction ◽  
Connexin 43 ◽  
Connexin 32 ◽  
Gap Junction Proteins ◽  
Junction Proteins

scholarly journals Photoperiod-Dependent Effects of 4-tert-Octylphenol on Adherens and Gap Junction Proteins in Bank Vole Seminiferous Tubules

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Anna Hejmej ◽  
Malgorzata Kotula-Balak ◽  
Katarzyna Chojnacka ◽  
Paulina Kuras ◽  
Marta Lydka-Zarzycka ◽  
...  
Keyword(s):  
Estrogen Receptor ◽  
Gap Junction ◽  
Bank Vole ◽  
Connexin 43 ◽  
Biological Effects ◽  
Seminiferous Tubules ◽  
Long Term Treatment ◽  
Gap Junction Proteins ◽  
Junction Proteins

In the present study we evaluatedin vivoandin vitroeffects of 4-tert-octylphenol (OP) on the expression and distribution of adherens and gap junction proteins, N-cadherin,β-catenin, and connexin 43 (Cx43), in testes of seasonally breeding rodents, bank voles. We found that in bank vole testes expression and distribution of N-cadherin,β-catenin, and Cx43 were photoperiod dependent. Long-term treatment with OP (200 mg/kg b.w.) resulted in the reduction of junction proteins expressions (P<0.05,P<0.01) and their delocalization in the testes of males kept in long photoperiod, whereas in short-day animals slight increase of Cx43 (P<0.05), N-cadherin, andβ-catenin (statistically nonsignificant) levels was observed. Effects of OP appeared to be independent of FSH and were maintained duringin vitroorgan culture, indicating that OP acts directly on adherens and gap junction proteins in the testes. An experiment performed using an antiestrogen ICI 182,780 demonstrated that the biological effects of OP onβ-catenin and Cx43 involve an estrogen receptor-mediated response. Taken together, in bank vole organization of adherens and gap junctions and their susceptibility to OP are related to the length of photoperiod. Alterations in cadherin/catenin and Cx43-based junction may partially result from activation of estrogen receptorαand/orβsignaling pathway.

Unilateral Effects of Pregnancy on Differential Expression of the Gap Junction Proteins Connexin 43 and 37 in Ovine Uterine Artery Endothelium.

2010 ◽  
Vol 83 (Suppl_1) ◽  
pp. 477-477
Author(s):  
Timothy J. Morschauser ◽  
Jayanth Ramadoss ◽  
Jill M. Koch ◽  
Gladys E. Lopez ◽  
Ian M. Bird ◽  
...  
Keyword(s):  
Gap Junction ◽  
Differential Expression ◽  
Connexin 43 ◽  
Uterine Artery ◽  
Unilateral Effects ◽  
Gap Junction Proteins ◽  
Junction Proteins

Differential Regulation of Gap Junction Proteins Connexin 40 and Connexin 43 in Cardiomyocytes

2004 ◽  
Vol 1 (1) ◽  
pp. 44-54 ◽  
Author(s):  
A. Salameh ◽  
K. Muhlberg . ◽  
P. Schneider . ◽  
S. Dhein . ◽  
D. Pfeiffer .
Keyword(s):  
Gap Junction ◽  
Connexin 43 ◽  
Differential Regulation ◽  
Connexin 40 ◽  
Gap Junction Proteins ◽  
Junction Proteins

Connexin 43 gap junction proteins are up-regulated in remyelinating spinal cord

2007 ◽  
Vol 85 (5) ◽  
pp. 945-953 ◽  
Author(s):  
W.A. Roscoe ◽  
E. Messersmith ◽  
A. Meyer-Franke ◽  
B. Wipke ◽  
S.J. Karlik
Keyword(s):  
Spinal Cord ◽  
Gap Junction ◽  
Connexin 43 ◽  
Gap Junction Proteins ◽  
Junction Proteins

Expression of the gap junction proteins connexin 26 and connexin 43 in human middle ear cholesteatoma

2006 ◽  
Vol 126 (2) ◽  
pp. 138-143 ◽  
Author(s):  
Yun-Hoon Choung ◽  
Keehyun Park ◽  
Sung-Ook Kang ◽  
Alexander Markov Raynov ◽  
Chul Ho Kim ◽  
...  
Keyword(s):  
Gap Junction ◽  
Middle Ear ◽  
Connexin 43 ◽  
Connexin 26 ◽  
Middle Ear Cholesteatoma ◽  
Gap Junction Proteins ◽  
Human Middle Ear ◽  
Junction Proteins

scholarly journals Differential regulation of the levels of three gap junction mRNAs in Xenopus embryos.

1990 ◽  
Vol 110 (3) ◽  
pp. 597-605 ◽  
Author(s):  
R L Gimlich ◽  
N M Kumar ◽  
N B Gilula
Keyword(s):  
Gap Junction ◽  
Connexin 43 ◽  
Sequence Similarity ◽  
Cdna Libraries ◽  
Amino Acid Sequence Similarity ◽  
Oocyte Growth ◽  
Gap Junction Proteins ◽  
Junction Proteins

Xenopus mRNAs that potentially encode gap junction proteins in the oocyte and early embryo have been identified by low-stringency screening of cDNA libraries with cloned mammalian gap junction cDNAs. The levels of these mRNAs show strikingly different temporal regulation and tissue distribution. Using a nomenclature designed to stress important structural similarities of distinct gap junction gene products, the deduced polypeptides have been designated the Xenopus alpha 1 and alpha 2 gap junction proteins. The alpha 2 gap junction mRNA is a maternal transcript that disappears by the late gastrula stage. It is not detected in any organ of the adult except the ovary, and resides primarily, if not exclusively, in the oocytes and early embryos. The alpha 1 gap junction mRNA appears during organogenesis, and is detected in RNA from a wide variety of organs. It is also found in full-grown oocytes, but is rapidly degraded upon oocyte maturation, both in vivo and in vitro. The alpha 1 and alpha 2 mRNAs encode proteins with different degrees of amino acid sequence similarity to the predominant gap junction subunit of the mammalian heart (connexin 43). Together with our earlier report of a mid-embryonic (beta 1) gap junction mRNA, the results suggest that intercellular communication during oocyte growth and postfertilization development is a complex phenomenon involving the coordinated regulation of several genes.

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