High-grade angiosarcoma of the right atrium successfully targeted with total resection and reconstruction followed by adjuvant chemotherapy

2014 ◽  
Author(s):  
Joost S. Vermaat ◽  
Alaaddin Yilmaz ◽  
Peter C. de Bruin ◽  
H. Wouter van Es ◽  
Martijn C. Post
Keyword(s):  
Adjuvant Chemotherapy ◽  
Right Atrium ◽  
High Grade ◽  
Total Resection ◽  
The Right

Desmoplastic infantile ganglioglioma with a malignant course

2008 ◽  
Vol 1 (1) ◽  
pp. 95-98 ◽  
Author(s):  
Eelco W. Hoving ◽  
Johan M. Kros ◽  
Ellis Groninger ◽  
Wilfred F. A. den Dunnen
Keyword(s):  
Adjuvant Chemotherapy ◽  
Clinical Course ◽  
High Grade ◽  
Primitive Cell ◽  
Glial Differentiation ◽  
Cell Component ◽  
Total Resection ◽  
Desmoplastic Infantile Ganglioglioma ◽  
Large Size ◽  
Supratentorial Tumors

✓Desmoplastic infantile gangliogliomas (DIGs) are rare supratentorial tumors that arise in infancy. Despite the large size of these lesions, the prognosis is generally considered favorable after gross-total resection (GTR); however, in incidental cases tumor progression has been described. The authors report on a child harboring a DIG with a high-grade primitive cell population and glial differentiation. The progressive clinical course was determined by this cell component in spite of GTR and adjuvant chemotherapy. The significance of the presence of a high-grade primitive tumor component in the context of DIG is discussed.

scholarly journals Dermatofibrosarcoma of the scalp

2019 ◽  
Vol 10 ◽  
pp. 221 ◽  
Author(s):  
Marcos Sangrador ◽  
Jimena González Olvera ◽  
Valeria Mendoza Ortiz
Keyword(s):  
Local Recurrence ◽  
Surgical Management ◽  
Dermatofibrosarcoma Protuberans ◽  
Gross Total Resection ◽  
High Grade ◽  
Rare Tumor ◽  
Parietal Region ◽  
Total Resection ◽  
History Of ◽  
The Right

A 25-year-old woman presented with a 4 months history of progressive pain and tumefaction in the right parietal region. Deformity of the scalp was evident, and a biopsy was taken, reporting a high- grade dermatofibrosarcoma. She underwent surgical management, achieving a gross total resection. Dermatofibrosarcoma protuberans is a rare tumor arising from the dermis. It tends to have an indolent course and local recurrence after excision.

scholarly journals High-Grade Inflammation Attenuates Chemosensitivity and Confers to Poor Survival of Surgical Stage III CRC Patients

2021 ◽  
Vol 11 ◽  
Author(s):  
Hou-Qun Ying ◽  
Xia-Hong You ◽  
Yu-Cui Liao ◽  
Fan Sun ◽  
Xue-Xin Cheng
Keyword(s):  
Adjuvant Chemotherapy ◽  
Primary Tumor ◽  
Tumor Location ◽  
Stage I ◽  
Stage Iii ◽  
Molecular Characteristics ◽  
Chemotherapy Response ◽  
High Grade ◽  
T4 Stage ◽  
The Right

Background: Heterogeneous clinical and molecular characteristics are reported in colorectal cancer (CRC) with different tumor laterality. However, the outcome of left- and right-sided patients with stage I–III CRC and the role of chronic inflammation in survival differences between them remain unclear.Method: A prospective study including 1,181 surgical patients with stage I–III CRC was carried out to investigate the involvement of circulating fibrinogen-to-pre-albumin (Alb) ratio (FPR) and primary tumor sidedness in the clinical outcome of those patients. We further investigated the effect of FPR on adjuvant chemotherapy response and recurrence in stage III patients.Results: Our study showed that the right tumor location was significantly associated with poor recurrence-free survival (RFS) (p = 0.04, adjusted HR = 1.41, 95% CI = 1.02–1.94) and overall survival (OS) (p = 0.04, adjusted HR = 1.55, 95% CI = 1.01–2.38) only in the stage III disease. In these patients, T4 stage distribution (83.39 vs. 70.94%, p < 0.01) within right-sided cases was significantly higher than left-sided patients. Moreover, preoperative FPR within right-sidedness (p < 0.01), T4 stage (p < 0.05), and large cancer bulk (≥5 cm) (p < 0.05) subgroups was significantly elevated compared to their counterparts, and it was gradually rising following the increased cancer bulk (p trend < 0.01). High-FPR distribution (52.30 vs. 27.00%, p < 0.01) within right-sided patients with the stage III disease was significantly higher than that in the left-sided cases. RFS (plog−rank < 0.01) and OS (plog−rank < 0.01) of the high-FPR patients were extremely inferior to the low-FPR cases, and the significant associations were observed when they were adjusted by other confounders including primary tumor location (p < 0.01, adjusted HR = 1.96, 95% CI = 1.42–2.70 for RFS; p < 0.01, adjusted HR = 2.44, 95% CI = 1.59–3.75 for OS). Additionally, RFS of adjuvant chemotherapy-treated high-FPR patients was superior to the patients without chemotherapy (plog−rank = 0.01) but was inferior to the low-FPR patients undergoing the treatment, especially in the 5-FU- and XELOX-treated subgroup.Conclusion: These findings indicate that chronic high-grade inflammation weakens chemotherapy efficacy and contributes to the poor prognosis of stage III surgical CRC patients.

WITHDRAWN: Enlargement of the Right Atrium – Diverticulum or Aneurysm?

2002 ◽  
Author(s):  
R KOBZA ◽  
E OECHSLIN ◽  
R PRETRE ◽  
D KURZ ◽  
R JENNI
Keyword(s):  
Right Atrium ◽  
The Right

Closure of Secundum Atrial Septal Defect with Autologous Right Atrial Patch: Case Report

2005 ◽  
Vol 8 (2) ◽  
pp. 96 ◽  
Author(s):  
Osman Tansel Dar�in ◽  
Alper Sami Kunt ◽  
Mehmet Halit Andac
Keyword(s):  
Atrial Septal Defect ◽  
Right Atrium ◽  
Septal Defect ◽  
Complete Recovery ◽  
Interatrial Septum ◽  
Right Atrial ◽  
Atrial Wall ◽  
Residual Shunt ◽  
Asd Closure ◽  
The Right

Background: Although various synthetic materials and pericardium have been used for atrial septal defect (ASD) closure, investigators are continuing to search for an ideal material for this procedure. We report and evaluate a case in which autologous right atrial wall tissue was used for ASD closure. Case: In this case, we closed a secundum ASD of a 22-year-old woman who also had right atrial enlargement due to the defect. After establishing standard bicaval cannulation and total cardiopulmonary bypass, we opened the right atrium with an oblique incision in a superior position to a standard incision. After examining the secundum ASD, we created a flap on the inferior rim of the atrial wall. A stay suture was stitched between the tip of the flap and the superior rim of the defect, and suturing was continued in a clockwise direction thereafter. Considering the size and shape of the defect, we incised the inferior attachment of the flap, and suturing was completed. Remnants of the flap on the inferior rim were resected, and the right atrium was closed in a similar fashion. Results: During an echocardiographic examination, neither a residual shunt nor perigraft thrombosis was seen on the interatrial septum. The patient was discharged with complete recovery. Conclusion: Autologous right atrial patch is an ideal material for ASD closure, especially in patients having a large right atrium. A complete coaptation was achieved because of the muscular nature of the right atrial tissue and its thickness, which is a closer match to the atrial septum than other materials.

Right Coronary Artery Fistula Draining into the Right Atrium and Associated with Mitral Valve Stenosis: A Case Report

2007 ◽  
Vol 10 (4) ◽  
pp. E325-E328 ◽  
Author(s):  
Ali Gürbüz ◽  
Ufuk Yetkin ◽  
Ömer Tetik ◽  
Mert Kestelli ◽  
Murat Yesil
Keyword(s):  
Case Report ◽  
Coronary Artery ◽  
Mitral Valve ◽  
Right Coronary Artery ◽  
Right Atrium ◽  
Coronary Artery Fistula ◽  
Mitral Valve Stenosis ◽  
The Right

Permanent Pacemaker Wire Vegetation in the Right Atrium

Circulation ◽  
1995 ◽  
Vol 92 (1) ◽  
pp. 148-148 ◽  
Author(s):  
Prasad Chalasani ◽  
David H. Montgomery ◽  
George L. Chang ◽  
Wacin Buddhari ◽  
Joel M. Felner
Keyword(s):  
Right Atrium ◽  
Permanent Pacemaker ◽  
The Right

Mitral Re-Repair and Right Coronary Fistula Closure Advantage of Minimally Invasive Approach

2010 ◽  
Vol 5 (6) ◽  
pp. 456-459 ◽  
Author(s):  
Vincenzo Giordano ◽  
Jan G. Grandjean
Keyword(s):  
Mitral Valve ◽  
Right Atrium ◽  
Mild Hypothermia ◽  
Posterior Wall ◽  
Coronary Arteriography ◽  
Coronary Fistula ◽  
Invasive Approach ◽  
Concomitant Procedure ◽  
Echocardiographic Images ◽  
The Right

A 51-year-old man developed severe mitral regurgitation 10 years after previous mitral valve repair; the echocardiographic images showed a remarkable eccentric jet toward posterior wall of left atrium associated with a high degree of pulmonary vein retrograde flow. The coronary arteriography pointed out no pathologic lesions but a coronary fistula from the proximal right coronary to the right atrium. The standard approach was avoided, and a right anterolateral minithoracotomy was chosen, providing an excellent view. Under cardiopulmonary bypass and mild hypothermia, the mitral valve was re-repaired, and a new ring was implanted. After aortic cross-clamp release, the right coronary fistula was closed through the right atrium. The postoperative course was uneventful, and the patient was discharged on the fourth postoperative day. In such a high-risk reintervention and concomitant procedure, we think that this different approach may represent a feasible and reliable alternative.

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