Laparoscopic intracorporeal anastomosis in the colon using the biofragmentable anastomotic ring - an animal study

1996 ◽  
Vol 11 (6) ◽  
pp. 299-302 ◽  
Author(s):  
F. Köckerling ◽  
I. Schneider ◽  
C. Schneider ◽  
W. Hohenberger
Keyword(s):  
Animal Study ◽  
Intracorporeal Anastomosis ◽  
Biofragmentable Anastomotic Ring

Regeneration of facial nerve after hypoglossal facial anastomosis: An animal study

1994 ◽  
Vol 111 (6) ◽  
pp. 710-716 ◽  
Author(s):  
Y CHEN ◽  
N YANAGIHARA ◽  
S MURAKAMI
Keyword(s):  
Facial Nerve ◽  
Animal Study

Validation of three‐dimensional echocardiographic principal strain analysis for assessing left ventricular contractility: An animal study

2019 ◽  
Vol 46 (5) ◽  
pp. 2137-2144
Author(s):  
Sahmin Lee ◽  
Seunghyun Choi ◽  
Sehwan Kim ◽  
Yeongjin Jeong ◽  
Kyusup Lee ◽  
...  
Keyword(s):  
Animal Study ◽  
Three Dimensional ◽  
Strain Analysis ◽  
Left Ventricular ◽  
Principal Strain ◽  
Ventricular Contractility ◽  
Left Ventricular Contractility

scholarly journals Effects of a new thyrotropic drug isolated from Potentilla alba on the male reproductive system of rats and offspring development

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Lubov V. Krepkova ◽  
Valentina V. Bortnikova ◽  
Aleksandra N. Babenko ◽  
Praskovya G. Mizina ◽  
Vladimir A. Mkhitarov ◽  
...  
Keyword(s):  
Animal Study ◽  
Male Fertility ◽  
Wistar Rats ◽  
Medical Condition ◽  
Adverse Outcomes ◽  
Female Rats ◽  
Childbearing Age ◽  
Offspring Development ◽  
Male Wistar Rats ◽  
And Control

Abstract Background The dysfunction of the thyroid gland is a common medical condition. Nowadays, patients frequently use medicinal herbs as complementary or alternative options to conventional drug treatments. These patients may benefit from treatment of thyroid dysfunctions with Potentilla alba L. preparations. While it has been reported that Potentilla alba preparations have low toxicity, nothing is known about their ability to affect reproductive functions in patients of childbearing age. Methods Male Wistar rats were orally treated with a thyrotrophic botanical drug, standardized Potentilla alba Dry Extract (PADE), at doses 8 and 40 times higher than the median therapeutic dose recommended for the clinical trials, for 60 consecutive days. Male Wistar rats receiving water (H2O) were used as controls. After completing treatment, half of the PADE-treated and control males were used to determine PADE gonadotoxicity, and the remaining half of PADE-treated and control males were mated with intact females. Two female rats were housed with one male for two estrus cycles. PADE effects on fertility and fetal/offspring development were evaluated. Results Herein, we report that oral treatment of male Wistar rats with PADE before mating with intact females instigated marked effects on male reproductive organs. Treatment significantly decreased the motility of the sperm and increased the number of pathological forms of spermatozoa. Additionally, a dose-dependent effect on Leydig cells was observed. However, these PADE effects did not significantly affect male fertility nor fetal and offspring development when PADE-treated males were mated with intact females. Conclusions PADE treatment of male rates negatively affected sperm and testicular Leydig cell morphology. However, these changes did not affect male fertility and offspring development. It is currently not known whether PADE treatment may affect human male fertility and offspring development. Therefore, these results from an animal study need to be confirmed in humans. Results from this animal study can be used to model the exposure-response relationship and adverse outcomes in humans.

scholarly journals Robotic natural-orifice IntraCorporeal anastomosis with Extraction (NICE procedure) for complicated diverticulitis

2021 ◽  
Author(s):  
Eric M. Haas ◽  
Thais Reif de Paula ◽  
Roberto Luna-Saracho ◽  
Melissa Sara Smith ◽  
Jean-Paul J. LeFave
Keyword(s):  
Complicated Diverticulitis ◽  
Intracorporeal Anastomosis ◽  
Natural Orifice ◽  
Abdominal Incision ◽  
Stepwise Approach ◽  
Stapling Device ◽  
Video Recordings ◽  
Conversion Rates ◽  
Technical Modifications ◽  
Instrument Control

Abstract Background Totally intracorporeal surgery for left-sided resection carries numerous potential advantages by avoiding crossing staple lines and eliminating the need for an abdominal incision. For those with complicated diverticulitis, minimally invasive surgery is known to be technically challenging due to inflamed tissue, distorted pelvic anatomy, and obliterated tissue planes, resulting in high conversion rates. We aim to illustrate the stepwise approach and modifications required to successful complete the robotic Natural-orifice IntraCorporeal anastomosis with transrectal specimen Extraction (NICE) procedure in this cohort. Methods Consecutive, elective, unselected patients presenting with complicated diverticulitis defined as fistula, abscess and stricture underwent the NICE procedure over a 24-month period. Demographic and intraoperative data were collected, and video recordings were reviewed and edited on encrypted server. Results A total of 60 patients (50% female) underwent the NICE procedure for complicated diverticulitis with a mean age of 58.9 years and mean BMI of 30.7 kg/m2. The mean operative time was 231.6 min. All cases (100%) were achieved with intracorporeal anastomosis using a circular stapling device. All but one patient (98.3%) had successful transrectal extraction of the specimen. Forty-four (73%) of the specimens required a specimen-thinning maneuver to successfully extract the specimen and there were no conversions. We identified seven key technical modifications and considerations to facilitate successful completion of the procedure which are illustrated, including early release of the disease, mesentery-sparing dissection, dual instrument control of the mesenteric vasculature, release of the rectal reflection, use of NICE back table, specimen-thinning maneuver, and closure of the rectal cuff. Conclusion We present a stepwise approach with key modifications to successfully achieve totally robotic intracorporeal resection for those presenting with complicated diverticulitis. This approach may help overcome the technical challenges and provide a foundation for reproducible results.

522 Influence of Secondary Dressings on the Effect of a Bacterial Derived Cellulose Dressing: Results of an Animal Study

2019 ◽  
Vol 40 (Supplement_1) ◽  
pp. S237-S237
Author(s):  
A C Tuca ◽  
M Funk ◽  
A Palackic ◽  
B Ives ◽  
F Groeber-Becker ◽  
...  
Keyword(s):  
Animal Study

scholarly journals Murphyʼs Button Revisited Clinical Experience With the Biofragmentable Anastomotic Ring

1993 ◽  
Vol 217 (1) ◽  
pp. 78-81 ◽  
Author(s):  
Kenneth A. Forde ◽  
Allison J. McLarty ◽  
June Tsai ◽  
Kourosh Ghalili ◽  
Harry M. Delany
Keyword(s):  
Clinical Experience ◽  
Biofragmentable Anastomotic Ring
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