Poorer prognosis for neuroendocrine carcinoma than signet ring cell cancer of the colon and rectum (CRC-NEC): a propensity score matching analysis of patients from the Surveillance, Epidemiology, and End Results (SEER) database

2021 ◽  
Author(s):  
Youwei Chen ◽  
Jiangfeng Tu ◽  
Shishi Zhou ◽  
Jianfei Fu ◽  
Qinghua Wang
Keyword(s):  
Propensity Score ◽  
Propensity Score Matching ◽  
Neuroendocrine Carcinoma ◽  
Cell Cancer ◽  
Signet Ring Cell ◽  
Seer Database ◽  
Propensity Score Matching Analysis ◽  
Signet Ring ◽  
Colon And Rectum ◽  
Ring Cell

scholarly journals Clinicopathologic Features of Signet-ring Cell Carcinoma of the Colon and Rectum

2006 ◽  
Vol 39 (1) ◽  
pp. 16-22 ◽  
Author(s):  
Tomoki Makino ◽  
Hideyuki Mishima ◽  
Masakazu Ikenaga ◽  
Toshimasa Tsujinaka ◽  
Masashi Takeda ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Clinicopathologic Features ◽  
Carcinoma Of The Colon ◽  
Signet Ring ◽  
Colon And Rectum ◽  
Ring Cell

scholarly journals Prognostic significance of frequent CLDN18-ARHGAP26/6 fusion in gastric signet-ring cell cancer

2018 ◽  
Vol 9 (1) ◽  
Author(s):  
Yang Shu ◽  
Weihan Zhang ◽  
Qianqian Hou ◽  
Linyong Zhao ◽  
Shouyue Zhang ◽  
...  
Keyword(s):  
Cell Cancer ◽  
Prognostic Significance ◽  
Signet Ring Cell ◽  
Signet Ring ◽  
Ring Cell

scholarly journals Effect of Age on Prognosis of Gastric Signet-Ring Cell Carcinoma: A SEER Database Analysis

2018 ◽  
Vol 24 ◽  
pp. 8524-8532 ◽  
Author(s):  
Jun Ren ◽  
Gengming Niu ◽  
Xin Wang ◽  
Tao Song ◽  
Zhiqing Hu ◽  
...  
Keyword(s):  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Seer Database ◽  
Database Analysis ◽  
Signet Ring ◽  
Ring Cell ◽  
Effect Of Age

Primary signet ring cell carcinoma of colon: Retrospective analysis of VACCR database.

2011 ◽  
Vol 29 (4_suppl) ◽  
pp. 58-58 ◽  
Author(s):  
R. Thota ◽  
T. Tashi ◽  
W. Gonsalves ◽  
V. Murukesan ◽  
P. Townley ◽  
...  
Keyword(s):  
Lymph Node ◽  
Cell Carcinoma ◽  
Mucinous Adenocarcinoma ◽  
Cell Cancer ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Lymph Node Status ◽  
Signet Ring ◽  
Ring Cell ◽  
Carcinoma Of Colon

58 Background: Signet ring cell carcinoma accounts for less than 1% of all colon cancers. We examined the clinical pathological features and prognosis of signet ring cell carcinoma of colon and compare it with mucinous and non-mucinous adenocarcinoma of colon. Methods: A total of 206 patients diagnosed with signet ring cell carcinoma from 1995 to 2009 were identified from the VA Central Cancer Registry (VACCR) database. Age, race, histology, grade, lymph node status, stage and type of treatment received data were collected. Results: Out of 206 patients, 173 (83.9%) were white, 31 (15%) were black, and 2 patients were listed as unknown. Median age of diagnosis was 67 years as compared to 70 years for both mucinous and non-mucinous adenocarcinoma of colon. Pathological T-stages were as follows: T1 = 2.9%, T2=5.3%, T3=33.9%, T4= 25.7%, and unknown 32%. Of the total, 22.3% were located in caecum, 21.8% in ascending colon, 15.5% in sigmoid colon, 7.7% in appendix and hepatic flexure of colon, 11.1% in transverse colon, 2.9% in splenic flexure and 4.4% in descending colon. 33.5% were lymph node positive, 34.6% were lymph node negative, and 31.8% were unknown. Histologically grade 3 (55.4%) was most commonly reported followed by grade 2 (7.3%), grade 1 (2.5%), grade 4 (1.9%)and in 33% grade was unknown. 41.3% patients received only surgery while 34% received surgery with adjuvant chemotherapy, 7.3% received chemotherapy alone and 7.8% patients received either chemotherapy, radiation or hormonal therapy alone, 9% did not receive any therapy. 1 year, 3 year and 5 year survivals for signet ring cell cancer compared to adeno carcinoma was 60% vs 80%, 33% vs 60%, and 24% vs 47% respectively. Median survival of signet ring cell carcinoma compared to mucinous and non mucinous adenocarcinoma was 19 months, 48 months and 62 months respectively. Conclusions: Signet ring cell carcinoma of colon has poor survival rates than the other histological subtypes. Signet ring cell carcinoma presents at an earlier age, higher tumor grade and advanced stage at diagnosis when compared to mucinous and non-mucinous adenocarcinoma of colon. Due to rarity of this disease further multi-institute studies are required for in-depth understanding and analysis of this disease. No significant financial relationships to disclose.

Primary signet-ring cell carcinoma of the colon and rectum

1995 ◽  
Vol 38 (11) ◽  
pp. 1189-1192 ◽  
Author(s):  
Luca Messerini ◽  
Annarita Palomba ◽  
Giancarlo Zampi
Keyword(s):  
Cell Carcinoma ◽  
Signet Ring Cell Carcinoma ◽  
Signet Ring Cell ◽  
Carcinoma Of The Colon ◽  
Signet Ring ◽  
Colon And Rectum ◽  
Ring Cell
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