Combined treatment with chemotherapy and radiation therapy for intracranial germ cell tumors

1998 ◽  
Vol 14 (1-2) ◽  
pp. 59-62 ◽  
Author(s):  
Masao Matsutani ◽  
Keiji Sano ◽  
Kintomo Takakura ◽  
Takamitsu Fujimaki ◽  
Osamu Nakamura
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Combined Treatment ◽  
Germ Cell Tumors ◽  
Intracranial Germ Cell Tumors

Radiation therapy for intracranial germ cell tumors: Predictive value of tumor response as evaluated by computed tomography

1997 ◽  
Vol 2 (2) ◽  
pp. 67-72 ◽  
Author(s):  
Kazuhiko Ogawa ◽  
Takafumi Toita ◽  
Yasumasa Kakinohana ◽  
Keiichiro Yamaguchi ◽  
Koichi Miyagi ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Radiation Therapy ◽  
Germ Cell ◽  
Predictive Value ◽  
Tumor Response ◽  
Germ Cell Tumors ◽  
Intracranial Germ Cell Tumors

scholarly journals Intensity-Modulated Radiation Therapy With Dose Painting: A Brain-Sparing Technique for Intracranial Germ Cell Tumors

2015 ◽  
Vol 63 (4) ◽  
pp. 646-651 ◽  
Author(s):  
Joanna C. Yang ◽  
Stephanie A. Terezakis ◽  
Ira J. Dunkel ◽  
Stephen W. Gilheeney ◽  
Suzanne L. Wolden
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
Intensity Modulated Radiation Therapy ◽  
Dose Painting ◽  
Intensity Modulated ◽  
Intracranial Germ Cell Tumors

Radiation therapy for intracranial germ cell tumors

2003 ◽  
Vol 56 (2) ◽  
pp. 511-518 ◽  
Author(s):  
Daphne A Haas-Kogan ◽  
Brian T Missett ◽  
William M Wara ◽  
Sarah S Donaldson ◽  
Kathleen R Lamborn ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
Intracranial Germ Cell Tumors

Radiation therapy for primary intracranial germ-cell tumors

1995 ◽  
Vol 32 (4) ◽  
pp. 943-949 ◽  
Author(s):  
Suzanne L. Wolden ◽  
William M. Wara ◽  
David A. Larson ◽  
Michael D. Prados ◽  
Michael S.B. Edwards ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Germ Cell Tumors ◽  
Intracranial Germ Cell Tumors

Primary intracranial germ cell tumors: a clinical analysis of 153 histologically verified cases

1997 ◽  
Vol 86 (3) ◽  
pp. 446-455 ◽  
Author(s):  
Masao Matsutani ◽  
Keiji Sano ◽  
Kintomo Takakura ◽  
Takamitsu Fujimaki ◽  
Osamu Nakamura ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Germ Cell ◽  
Malignant Tumors ◽  
Survival Rates ◽  
Germ Cell Tumors ◽  
Surgical Removal ◽  
Content Type ◽  
Intracranial Germ Cell Tumors ◽  
Mixed Tumors ◽  
Fine Print

✓ The authors analyzed 153 cases of histologically verified intracranial germ cell tumors. The histological diagnosis was germinoma in 63 patients (41.2%), teratoma in 30 (19.6%), and other types of tumors in 60 patients (39.2%). The patients were treated by a consistent policy of surgical removal with histological verification followed by radiation therapy with or without chemotherapy. The 10- and 20-year survival rates of patients with pure germinoma were 92.7% and 80.6%, respectively. The 10-year survival rates of patients with mature teratoma and malignant teratoma were 92.9% and 70.7%, respectively. Patients with pure malignant germ cell tumors (embryonal carcinoma, yolk sac tumor, or choriocarcinoma) had a 3-year survival rate of 27.3%. The mixed tumors were divided into three subgroups: 1) mixed germinoma and teratoma; 2) mixed tumors whose predominant characteristics were germinoma or teratoma combined with some elements of pure malignant tumors; and 3) mixed tumors with predominantly pure malignant elements. The 3-year survival rates were 94.1% for the first group, 70% for the second group, and 9.3% for the third group, and the differences were statistically significant. Twenty-six patients with malignant tumors received chemotherapy that consisted of cisplatin and carboplatin combinations with or without radiation therapy. However, chemotherapy was not significantly more effective than radiation therapy alone. From these treatment results, the authors classified tumors into three groups with different prognoses and proposed a treatment guideline appropriate for the subgroups.

c-Kit gene mutations in intracranial germ cell tumors

2010 ◽  
Vol 222 (03) ◽  
Author(s):  
B Steiger ◽  
O Schmidt ◽  
T Pietsch
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Gene Mutations ◽  
Intracranial Germ Cell Tumors ◽  
Kit Gene

Primary Intracranial Germ Cell Tumors: Clinicopathologic Review of 32 Cases

1997 ◽  
Vol 17 (5) ◽  
pp. 713-727
Author(s):  
K. L. Salzman ◽  
A. M. Rojiani ◽  
J. Buatti ◽  
R. G. Quisling ◽  
R. B. Marcus ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Intracranial Germ Cell Tumors

Fractionated brachytherapy accelerates absorption of intratumoral hemorrhage in intracranial germ cell tumors

2010 ◽  
Vol 29 (12) ◽  
pp. 1440-1441
Author(s):  
Ci-na ZHENG ◽  
Jin-lin WANG ◽  
Xiang-sheng XIAO ◽  
Shi-yuan LIU ◽  
Zeng-ru SHI ◽  
...  
Keyword(s):  
Germ Cell ◽  
Germ Cell Tumors ◽  
Intratumoral Hemorrhage ◽  
Intracranial Germ Cell Tumors
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