H + and Cl − secretion in the stomach of the teleost fish, Anguilla anguilla  : stimulation by histamine and carbachol

1998 ◽  
Vol 168 (1) ◽  
pp. 1-8 ◽  
Author(s):  
F. Trischitta ◽  
M. G. Denaro ◽  
C. Faggio ◽  
M. Mandolfino ◽  
T. Schettino
Keyword(s):  
Teleost Fish ◽  
Anguilla Anguilla ◽  
Cl Secretion ◽  
Stimulation By Histamine

STUDIES ON THE PRESSOR SUBSTANCES OF THE CAUDAL NEUROSECRETORY SYSTEM OF TELEOST FISH: BIOASSAY AND FRACTIONATION

1969 ◽  
Vol 45 (2) ◽  
pp. 151-159 ◽  
Author(s):  
D. K. O. CHAN ◽  
I. CHESTER JONES ◽  
S. PONNIAH
Keyword(s):  
Small Molecules ◽  
Teleost Fish ◽  
Anguilla Anguilla ◽  
Neurosecretory System ◽  
Active Molecule ◽  
Caudal Neurosecretory System ◽  
Disulphide Bonds

SUMMARY A method for the bioassay of the pressor substances in extracts of the urophyses of the teleost fish, Mugil auratus and Anguilla anguilla, is described. Ultracentrifugation, chromatography on Sephadex gel and treatment with trypsin and papain showed that the pressor principles are polypeptides. One fraction was protein-bound while two other fractions seem to be small molecules. Treatment with thioglycollate showed that disulphide bonds do not form an integral part of the active molecule. The possible function of these principles in the control of the caudal circulation is discussed.

Chloride transport of frog gastric fundus: effects of omeprazole

1986 ◽  
Vol 250 (1) ◽  
pp. G118-G126 ◽  
Author(s):  
M. J. Starlinger ◽  
M. J. Hollands ◽  
P. H. Rowe ◽  
J. B. Matthews ◽  
W. Silen
Keyword(s):  
Chloride Transport ◽  
Electrical Response ◽  
Short Circuit ◽  
Basolateral Membrane ◽  
Short Circuit Current ◽  
Gastric Fundus ◽  
Open Circuit ◽  
Cl Secretion ◽  
Transient Rise ◽  
Stimulation By Histamine

Omeprazole (10(-4) M) inhibited H+ secretion and increased potential difference (PD), resistance, and short-circuit current (Isc) in chambered bullfrog gastric mucosa, but the electrical changes developed only in tissues previously exposed to histamine. Net chloride transport (JnetCl) did not change after omeprazole under short-circuited conditions, and Isc increased to become equal to JnetCl. Under open-circuit conditions, JnetCl was reduced by 38%, the decrement attributable to the concomitant increase in PD, as evidenced by a linear relationship between JnetCl and PD in omeprazole-treated mucosae clamped to different PD (0-45 mV). The effect of omeprazole on PD and Isc could be blocked by metiamide and was absent in spontaneously resting tissues. HEPES nutrient solutions did not alter the electrical response or Cl- transport after omeprazole. In Na+-free solutions, omeprazole induced only a transient rise in PD and Isc. We conclude that omeprazole uncouples H+ and Cl- secretion. This Cl- secretion is electrogenic and dependent upon stimulation by histamine. Both Na+ and HCO3- seem to be involved in movement of Cl- across the basolateral membrane.

Effects of CdCl2 on electrophysiological parameters in the intestine of the teleost fish, Anguilla anguilla

1998 ◽  
Vol 41 (3) ◽  
pp. 251-264 ◽  
Author(s):  
M.G Lionetto ◽  
S Vilella ◽  
F Trischitta ◽  
M.S Cappello ◽  
M.E Giordano ◽  
...  
Keyword(s):  
Teleost Fish ◽  
Anguilla Anguilla

Ammonia inhibition of active electrogenic Cl− secretion in both human and rat colon: does a regulatory apical K+ conductance exist?

2001 ◽  
Vol 120 (5) ◽  
pp. A529-A529
Author(s):  
J MAYOL ◽  
T OBRIEN ◽  
P ALAMAESTRANY ◽  
J SONG ◽  
M PRASAD ◽  
...  
Keyword(s):  
Rat Colon ◽  
Ammonia Inhibition ◽  
Cl Secretion

Ca2+-dependent Cl− secretion in T84 epithelia: Role of SOCs and Na+−K+ ATPase

2001 ◽  
Vol 120 (5) ◽  
pp. A527-A527
Author(s):  
J SONG ◽  
P RANGACHARI ◽  
J MATTHEWS
Keyword(s):  
Cl Secretion

Chemically Contaminated Eel Fed to Pregnant and Lactating Mouse Dams Causes Hyperactivity in Their Offspring

2016 ◽  
Vol 86 (1-2) ◽  
pp. 36-47 ◽  
Author(s):  
Imen Dridi ◽  
Nidhal Soualeh ◽  
Torsten Bohn ◽  
Rachid Soulimani ◽  
Jaouad Bouayed
Keyword(s):  
Open Field ◽  
Early Life ◽  
Home Cage ◽  
Anguilla Anguilla ◽  
Acetylcholinesterase Activity ◽  
Female Offspring ◽  
Significant Inhibition ◽  
Standard Diet ◽  
Early Life Exposure ◽  
Cage Test

Abstract.This study examined whether perinatal exposure to polluted eels (Anguilla anguilla L.) induces changes in the locomotor activity of offspring mice across lifespan (post-natal days (PNDs) 47 – 329), using the open field and the home cage activity tests. Dams were exposed during gestation and lactation, through diets enriched in eels naturally contaminated with pollutants including PCBs. Analysis of the eel muscle focused on the six non-dioxin-like (NDL) indicator PCBs (Σ6 NDL-PCBs: 28, 52, 101, 138, 153 and 180). Four groups of dams (n = 10 per group) received either a standard diet without eels or eels (0.8 mg/kg/day) containing 85, 216, or 400 ng/kg/day of ϵ6 NDL-PCBs. The open field test showed that early-life exposure to polluted eels increased locomotion in female offspring of exposed dams but not in males, compared to controls. This hyperlocomotion appeared later in life, at PNDs 195 and 329 (up to 32 % increase, p < 0.05). In addition, overactivity was observed in the home cage test at PND 305: exposed offspring females showed a faster overall locomotion speed (3.6 – 4.2 cm/s) than controls (2.9 cm/s, p <0.05); again, males remained unaffected. Covered distances in the home cage test were only elevated significantly in offspring females exposed to highest PCB concentrations (3411 ± 590 cm vs. 1377 ± 114 cm, p < 0.001). These results suggest that early-life exposure to polluted eels containing dietary contaminants including PCBs caused late, persistent and gender-dependent neurobehavioral hyperactive effects in offspring mice. Furthermore, female hyperactivity was associated with a significant inhibition of acetylcholinesterase activity in the hippocampus and the prefrontal cortex.

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