Genomic structure, cDNA mapping, and chromosomal localization of the mouse homeobox gene, Hex

1999 ◽  
Vol 10 (10) ◽  
pp. 1023-1025 ◽  
Author(s):  
Bidyut Ghosh ◽  
Harris C. Jacobs ◽  
Leanne M. Wiedemann ◽  
Anthony Brown ◽  
Fiona K. Bedford ◽  
...  
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
Homeobox Gene

Genomic structure, chromosomal localization and expression of the human LIM–homeobox gene LHX5

Gene ◽  
2000 ◽  
Vol 260 (1-2) ◽  
pp. 95-101 ◽  
Author(s):  
Yangu Zhao ◽  
Edit Hermesz ◽  
Maria C Yarolin ◽  
Heiner Westphal
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
Homeobox Gene

scholarly journals Genomic Structure and Chromosomal Localization of the Mouse LIM/Homeobox Gene Lhx3

Genomics ◽  
1995 ◽  
Vol 27 (1) ◽  
pp. 27-32 ◽  
Author(s):  
Alexander B. Zhadanov ◽  
Neal G. Copeland ◽  
Debra J. Gilbert ◽  
Nancy A. Jenkins ◽  
Heiner Westphal
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
Homeobox Gene

GENOMIC STRUCTURE AND CHROMOSOMAL LOCALIZATION OF THE HUMAN INTERLEUKIN 15 GENE (IL–15)

Cytokine ◽  
1996 ◽  
Vol 8 (9) ◽  
pp. 667-674 ◽  
Author(s):  
Hans Krause ◽  
Burkhard Jandrig ◽  
Catrin Wernicke ◽  
Silvia Bulfone-Paus ◽  
Thomas Pohl ◽  
...  
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
Interleukin 15

Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism

Development ◽  
1999 ◽  
Vol 126 (24) ◽  
pp. 5749-5758 ◽  
Author(s):  
K. Kitamura ◽  
H. Miura ◽  
S. Miyagawa-Tomita ◽  
M. Yanazawa ◽  
Y. Katoh-Fukui ◽  
...  
Keyword(s):  
Body Wall ◽  
Genomic Structure ◽  
Homeobox Gene ◽  
Lacz Gene ◽  
Mitral Valves ◽  
Lateral Body ◽  
Asymmetrical Pattern ◽  
Ocular System ◽  
Deficient Mice ◽  
Pitx2 Expression

Pitx2, a bicoid-related homeobox gene, is involved in Rieger's syndrome and the left-right (L-R) asymmetrical pattern formation in body plan. In order to define the genomic structure and roles of Pitx2, we analyzed the genomic structure and generated Pitx2-deficient mice with the lacZ gene in the homeobox-containing exon of Pitx2. We were able to show that among three isoforms of Pitx2, Pitx2c shows asymmetrical expression whereas Pitx2a, Pitx2b and Pitx2c show symmetrical expression. In Pitx2(−)(/)(−) embryos there was an increase in mesodermal cells in the distal end of the left lateral body wall and an amnion continuous with the lateral body wall thickened in its mesodermal layer. These changes resulted in a failure of ventral body wall closure. In lung and heart in which Pitx2 is expressed asymmetrically, right pulmonary isomerism, atrioventricular canals with prominent swelling, and juxtaposition of the atrium were detected. The hearts failed to develop tricuspid and mitral valves and a common atrioventricular valve forms. Further, dysgenesis of the Pitx2(−)(/)(−) extraocular muscle and thickening of the mesothelial layer of cornea were observed in the ocular system where Pitx2 is expressed symmetrically, and these resulted in enophthalmos. The present study shows that Pitx2 expressed in various sites participates in morphogenesis through three types of actions: the involvement of asymmetric Pitx2 expression in the entire morphogenetic process of L-R asymmetric organs; the involvement of asymmetric Pitx2 expression in the regional morphogenesis of asymmetric organs; and finally the involvement of symmetric Pitx2 expression in the regional morphogenesis of symmetric organs.

Genomic Structure, Chromosomal Localization, and Expression of Human Cathepsin W

1998 ◽  
Vol 248 (2) ◽  
pp. 255-261 ◽  
Author(s):  
Th. Wex ◽  
B. Levy ◽  
S.P. Smeekens ◽  
S. Ansorge ◽  
R.J. Desnick ◽  
...  
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
Human Cathepsin ◽  
Cathepsin W

Genomic structure and refined chromosomal localization of the mouse Ptch2 gene

2002 ◽  
Vol 97 (1-2) ◽  
pp. 106-110 ◽  
Author(s):  
L. Fröhlich ◽  
Z. Liu ◽  
D.R. Beier ◽  
B. Lanske
Keyword(s):  
Chromosomal Localization ◽  
Genomic Structure ◽  
I Gene

Genomic structure and chromosomal localization of the rat protein kinase Cδ-gene

Gene ◽  
2000 ◽  
Vol 242 (1-2) ◽  
pp. 115-123 ◽  
Author(s):  
Kaisa M.A. Kurkinen ◽  
Riitta A. Keinänen ◽  
Ritva Karhu ◽  
Jari Koistinaho
Keyword(s):  
Protein Kinase ◽  
Chromosomal Localization ◽  
Genomic Structure ◽  
Protein Kinase Cδ

Characterization of the mouse beta-prime adaptin gene; cDNA sequence, genomic structure, and chromosomal localization

1997 ◽  
Vol 8 (9) ◽  
pp. 651-656 ◽  
Author(s):  
Cécile Guilbaud ◽  
Myriam Peyrard ◽  
Ingegerd Fransson ◽  
Sandra W. Clifton ◽  
Bruce A. Roe ◽  
...  
Keyword(s):  
Cdna Sequence ◽  
Chromosomal Localization ◽  
Genomic Structure
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