The clf1 gene maps to a 2- to 3-cM region of distal mouse Chromosome 11

1996 ◽  
Vol 7 (10) ◽  
pp. 789-789 ◽  
Author(s):  
D. M. Juriloff ◽  
M. J. Harris ◽  
D. G. Mah
1996 ◽  
Vol 93 (26) ◽  
pp. 15352-15357 ◽  
Author(s):  
K. L. Mohlke ◽  
W. C. Nichols ◽  
R. J. Westrick ◽  
E. K. Novak ◽  
K. A. Cooney ◽  
...  

Genetics ◽  
1992 ◽  
Vol 132 (1) ◽  
pp. 241-246
Author(s):  
C Sapienza ◽  
J Paquette ◽  
P Pannunzio ◽  
S Albrechtson ◽  
K Morgan

Abstract Genome imprinting is the process by which identical alleles at a particular locus may be rendered functionally different depending on the sex of the parent contributing the allele. While several mutations in imprinted genes have been defined, no variants in the regulatory system that gives rise to imprinting have been described. Here we report our genetic analysis of the behavior of the interstrain, polar, embryonic-lethal phenotype known as the "DDK syndrome." We have mapped the interstrain, polar-lethal region of the genome to the distal portion of mouse chromosome 11, near the Xmv-42 locus. We propose that the lethal phenotype is not caused by a standard mutation, but by aberrant imprinting of a gene within this region.


1994 ◽  
Vol 5 (12) ◽  
pp. 805-806 ◽  
Author(s):  
E. H. Birkenmeier ◽  
L. B. Rowe ◽  
M. W. Crossman ◽  
J. I. Gordon

Genetics ◽  
2002 ◽  
Vol 161 (4) ◽  
pp. 1651-1659 ◽  
Author(s):  
Elena de la Casa-Esperón ◽  
J Concepción Loredo-Osti ◽  
Fernando Pardo-Manuel de Villena ◽  
Tammi L Briscoe ◽  
Jan Michel Malette ◽  
...  

AbstractWe observed that maternal meiotic drive favoring the inheritance of DDK alleles at the Om locus on mouse chromosome 11 was correlated with the X chromosome inactivation phenotype of (C57BL/ 6-Pgk1a × DDK)F1 mothers. The basis for this unexpected observation appears to lie in the well-documented effect of recombination on meiotic drive that results from nonrandom segregation of chromosomes. Our analysis of genome-wide levels of meiotic recombination in females that vary in their X-inactivation phenotype indicates that an allelic difference at an X-linked locus is responsible for modulating levels of recombination in oocytes.


1996 ◽  
Vol 7 (2) ◽  
pp. 163-163
Author(s):  
G. C. Voss ◽  
H. Jockusch

Sign in / Sign up

Export Citation Format

Share Document