Coding sequence, chromosomal localization, and expression pattern of Nrf1: the mouse homolog of Drosophila erect wing

2000 ◽  
Vol 11 (2) ◽  
pp. 104-110 ◽  
Author(s):  
Laura Schaefer ◽  
Heather Engman ◽  
Jeffrey B. Miller
Keyword(s):  
Expression Pattern ◽  
Chromosomal Localization ◽  
Mouse Homolog ◽  
Coding Sequence

scholarly journals The Drosophila engrailed and invected Genes: Partners in Regulation, Expression and Function

Genetics ◽  
1996 ◽  
Vol 142 (3) ◽  
pp. 893-906 ◽  
Author(s):  
Elizabeth Gustavson ◽  
Andrew S Goldsborough ◽  
Zehra Ali ◽  
Thomas B Kornberg
Keyword(s):  
Expression Pattern ◽  
Cultured Cells ◽  
Regulatory Region ◽  
Embryonic Lethality ◽  
Wild Type ◽  
Terminal Portion ◽  
Coding Sequence ◽  
Differential Effects ◽  
And Function ◽  
Redundant Functions

Abstract We isolated and characterized numerous engrailed and invected alleles. Among the deficiencies we isolated, a mutant lacking invected sequences was viable and phenotypically normal, a mutant lacking engrailed was an embryo lethal and had slight segmentation defects, and a mutant lacking both engrailed and invected was most severely affected. In seven engrailed alleles, mutations caused translation to terminate prematurely in the central or C-terminal portion of the coding sequence, resulting in embryonic lethality and segmentation defects. Both engrailed and invected expression declined prematurely in these mutant embryos. In wild-type embryos, engrailed and invected are juxtaposed and are expressed in essentially identical patterns. A breakpoint mutant that separates the mgrailed and invected transcription units parceled different aspects of the expression pattern to engrailed or invected. We also found that both genes cause similar defects when expressed ectopically and that the protein products of both genes act to repress transcription in cultured cells. We propose that the varied phenotypes of the engrailed alleles can be explained by the differential effects these mutants have on the combination of engrailed and invected activities, that engrailed and invected share a regulatory region, and that they encode redundant functions.

Molecular Cloning, Expression Pattern, and Chromosomal Localization of Human CDKN2D/INK4d,an Inhibitor of Cyclin D-Dependent Kinases

Genomics ◽  
1995 ◽  
Vol 29 (3) ◽  
pp. 623-630 ◽  
Author(s):  
TSUKASA OKUDA ◽  
HIROSHI HIRAI ◽  
VIRGINIA A. VALENTINE ◽  
SHEILA A. SHURTLEFF ◽  
VINCENT J. KIDD ◽  
...  
Keyword(s):  
Molecular Cloning ◽  
Expression Pattern ◽  
Chromosomal Localization ◽  
Cyclin D

Chromosomal Localization of the Mouse Homolog of the Huntington's Disease Linked G8 (D4S10) Marker

DNA ◽  
1987 ◽  
Vol 6 (5) ◽  
pp. 401-407 ◽  
Author(s):  
SHIRLEY V. CHENG ◽  
TRACY GROSS LUGO ◽  
RUDOLPH E. TANZI ◽  
JOHN B. WHITNEY ◽  
R.E.K. FOURNIER ◽  
...  
Keyword(s):  
Huntington's Disease ◽  
Huntington’S Disease ◽  
Chromosomal Localization ◽  
Mouse Homolog

Cloning and chromosomal localization of a paralog and a mouse homolog of the human transaldolase gene

Gene ◽  
1998 ◽  
Vol 209 (1-2) ◽  
pp. 13-21 ◽  
Author(s):  
Jun Kusuda ◽  
Momoki Hirai ◽  
Atsushi Toyoda ◽  
Reiko Tanuma ◽  
Aya Nomura-Kitabayashi ◽  
...  
Keyword(s):  
Chromosomal Localization ◽  
Mouse Homolog

Cloning, Expression Pattern, Chromosomal Localization, and Evolution Analysis of Porcine Gnaq, Gna11, and Gna14

2008 ◽  
Vol 46 (7-8) ◽  
pp. 398-405 ◽  
Author(s):  
Huaping Chen ◽  
Wenshu Yao ◽  
Dan Jin ◽  
Tao Xia ◽  
Xiaodong Chen ◽  
...  
Keyword(s):  
Expression Pattern ◽  
Chromosomal Localization ◽  
Evolution Analysis
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