Degenerative joint disease on MRI and physical activity: a clinical study of the knee joint in 320 patients

1999 ◽  
Vol 9 (1) ◽  
pp. 145-152 ◽  
Author(s):  
G. F. Bachmann ◽  
E. Basad ◽  
K. Rauber ◽  
M. S. Damian ◽  
W. S. Rau
Keyword(s):  
Physical Activity ◽  
Clinical Study ◽  
Knee Joint ◽  
Degenerative Joint Disease ◽  
Joint Disease

scholarly journals Sports Activity Following Cementless Metaphyseal Hip Joint Arthroplasty

2017 ◽  
Vol 60 (1) ◽  
pp. 225-232
Author(s):  
Szymon Czech ◽  
Jacek Hermanson ◽  
Piotr Rodak ◽  
Tomasz Stołtny ◽  
Łukasz Rodak ◽  
...  
Keyword(s):  
Physical Activity ◽  
Hip Joint ◽  
Degenerative Joint Disease ◽  
Joint Arthroplasty ◽  
Joint Disease ◽  
Harris Hip Score ◽  
Joint Diseases ◽  
Sports Activity ◽  
Level Of Functioning ◽  
Degenerative Joint Diseases

Abstract An adequate level of physical activity has a substantial effect on both mental and physical human health. Physical activity is largely dependent on the function of the musculoskeletal and articular system. One of the most frequent diseases of this system is degenerative joint disease. Due to the changing and more demanding lifestyles and patients’ willingness to be involved in sports activity, the expectations of hip joint arthroplasty are becoming increasingly high. Alleviating pain ceases to be the only reason for which patients choose surgical interventions, while the expectations often include involvement in various sports. Only few studies contain recommendations concerning the frequency, type and intensity of sports activity which are acceptable after hip joint arthroplasty. The aim of the study was to evaluate function and physical activity of people following cementless short-stem hip joint arthroplasty in the observation of at least five years. The study group comprised 106 patients who underwent total hip arthroplasty due to degenerative joint diseases, chosen according to inclusion criteria. Patients underwent routine physical examinations following the Harris Hip Score protocol, responded to the UCLA scale and questionnaires concerning pre-surgical and current physical activity. Our results demonstrated that hip joint arthroplasty in people suffering from degenerative joint diseases has a beneficial effect on their level of functioning and physical activity. Although physical activity and the level of functioning obviously reduced as a person aged, the level of physical activity continued to be very high in both groups, with function of the hip joint evaluated as very good.

scholarly journals Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging

2022 ◽  
Vol 12 (1) ◽  
Author(s):  
Nathalie Accart ◽  
Janet Dawson ◽  
Michael Obrecht ◽  
Christian Lambert ◽  
Manuela Flueckiger ◽  
...  
Keyword(s):  
Knee Joint ◽  
Inflammatory Cells ◽  
Cyst Formation ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Infrapatellar Fat Pad ◽  
Monosodium Urate ◽  
Fat Pad ◽  
Crystal Deposition ◽  
Translational Imaging

AbstractThe objective of this work was to assess the consequences of repeated intra-articular injection of monosodium urate (MSU) crystals with inflammasome priming by lipopolysaccharide (LPS) in order to simulate recurrent bouts of gout in rats. Translational imaging was applied to simultaneously detect and quantify injury in different areas of the knee joint. MSU/LPS induced joint swelling, synovial membrane thickening, fibrosis of the infrapatellar fat pad, tidemark breaching, and cartilage invasion by inflammatory cells. A higher sensitivity to mechanical stimulus was detected in paws of limbs receiving MSU/LPS compared to saline-injected limbs. In MSU/LPS-challenged joints, magnetic resonance imaging (MRI) revealed increased synovial fluid volume in the posterior region of the joint, alterations in the infrapatellar fat pad reflecting a progressive decrease of fat volume and fibrosis formation, and a significant increase in the relaxation time T2 in femoral cartilage, consistent with a reduction of proteoglycan content. MRI also showed cyst formation in the tibia, femur remodeling, and T2 reductions in extensor muscles consistent with fibrosis development. Repeated intra-articular MSU/LPS injections in the rat knee joint induced pathology in multiple tissues and may be a useful means to investigate the relationship between urate crystal deposition and the development of degenerative joint disease.

scholarly journals The Role of Fibrosis in Osteoarthritis Progression

Life ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 3
Author(s):  
Yeri Alice Rim ◽  
Ji Hyeon Ju
Keyword(s):  
Knee Joint ◽  
Total Joint Replacement ◽  
Cartilage Degeneration ◽  
Critical Issue ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Joint Movement ◽  
Synovial Membrane Inflammation ◽  
Osteoarthritis Progression

Osteoarthritis (OA) is a chronic degenerative joint disease where the main characteristics include cartilage degeneration and synovial membrane inflammation. These changes in the knee joint eventually dampen the function of the joint and restrict joint movement, which eventually leads to a stage where total joint replacement is the only treatment option. While much is still unknown about the pathogenesis and progression mechanism of OA, joint fibrosis can be a critical issue for better understanding this disease. Synovial fibrosis and the generation of fibrocartilage are the two main fibrosis-related characteristics that can be found in OA. However, these two processes remain mostly misunderstood. In this review, we focus on the fibrosis process in OA, especially in the cartilage and the synovium tissue, which are the main tissues involved in OA.

scholarly journals A Case Study of Janusandhigatavata (Osteoarthritis of knee joint)

2020 ◽  
Vol 8 (05) ◽  
Author(s):  
Dr Anushri Gokul Endait
Keyword(s):  
Physical Activity ◽  
Knee Joint ◽  
Joint Disease ◽  
Knee Joints ◽  
Restricted Movement ◽  
Osteoarthritis Of Knee ◽  
Before And After ◽  
Subjective Sign

            Osteoarthritis is one of the most common disorders in joint disease. It is characterized by pain, shiftiness, decreased range of motion which is very close to Sandhigatavat. Sandhigatavat is amongst 80 Nanatmaj Vat Vyadhi. Here is a case of 57 years old male patient who was having complaints        of pain, tenderness, crepitus, swelling and restricted movement of both knee joints. Based on these symptoms and clinical sign he was diagnosed as a case of Sandhigatvat. Treatment given to this patient was Snehan, Swedan, Janubasti, Yog, Basti and oral medication . Assessment of patient before and after treatment was done on the basis of pain, tenderness and physical activity to exclude the efficacy of the treatment. Based on assessment parameter, moderate improvement was seen in subjective sign & symptoms after the completion of Schedule of IPD treatment & 1 month follow up. The pain & physical activity were improved significantly.

scholarly journals Relationship between Radiological Severity, Knee Pain and Functional Limitation in Patients With Knee Osteoarthritis at Dr. M. Djamil Padang General Hospital

2021 ◽  
Vol 5 (11) ◽  
pp. 997-1004
Author(s):  
Yona Riapesi ◽  
Rizki Rahmadian ◽  
Hendra Maska
Keyword(s):  
Knee Joint ◽  
Pain Intensity ◽  
Functional Limitation ◽  
Degenerative Joint Disease ◽  
Joint Disease ◽  
Moderate Intensity ◽  
P Value ◽  
Physical Capability ◽  
Fourth Degree ◽  
Study Results

Background: Osteoarthritis (OA) is a degenerative joint disease frequently affecting the elderly and the middle class due to injury or overuse of the joints. An individual with pain due to OA will experience dysfunction of joints and muscles, thus causing movement limitation, decrease of muscle strength and balance. The objective of this study is to know the association of OA radiological degree with pain intensity and limitation of physical capability in patients with knee joint OA. Methods: This study is a retrospective study on patients with knee joint OA treated at RSUP Dr. M. Djamil Padang in year 2021 from January 2021 to May 2021. Data collection was conducted in the Medical Records Department of RSUP Dr. M. Djamil Padang and questionnaire which fulfills the inclusion and exclusion criteria. Results: A total of 58 patients fulfilled the inclusion criteria of this study. Results of the study showed the mean age of the respondents was 60 years with variance of 7 years. More than a half (77.6%) of the respondents were female and most common ethnicity was Minang (82.8%). 50% of the patients were housewives. BMI of the respondents were mostly overweight - obese (65.5%). Most commonly affected side of the knee joint OA was the right side (55.2%). Most common degree of OA was the fourth degree (39.7%). More than a half of the respondents (84.5%) had moderate intensity of pain and 34.5% respondents had mild physical limitation. Results of the study showed that there was an association between OA radiological degree and pain intensity in patients with knee joint OA (p value = 0.0001). Results of the study showed that there was an association between OA radiological degree and level of physical capability limitations in patients with knee joint OA (p value = 0.0001). Results of the study showed that there was an association between pain intensity and level of physical capability limitations in patients with knee joint OA (p value = 0.0001). Conclusion: There was an association between OA radiological degree and pain intensity, physical limitations in patients with knee joint OA, and there was an association between pain intensity and level of physical capability limitation in patients with knee joint OA.

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