Quantitation of dolastatin-10 using HPLC/electrospray ionization mass spectrometry: application in a phase I clinical trial

1998 ◽  
Vol 41 (4) ◽  
pp. 299-306 ◽  
Author(s):  
D. A. Garteiz ◽  
T. Madden ◽  
D. E. Beck ◽  
W. R. Huie ◽  
K. T. McManus ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Clinical Trial ◽  
Phase I ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Phase I Clinical Trial ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Mass Spectrometry Application ◽  
Dolastatin 10

Specific interactions of leucine with disaccharides by electrospray ionization mass spectrometry: application to rapid differentiation of disaccharide isomers in combination with statistical analysis

The Analyst ◽  
2015 ◽  
Vol 140 (23) ◽  
pp. 7965-7973 ◽  
Author(s):  
Hang Yuan ◽  
Jianxi Ying ◽  
Peiran Deng ◽  
Peng Chen ◽  
Jinwen Shi ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Statistical Analysis ◽  
Tandem Mass Spectrometry ◽  
Electrospray Ionization ◽  
Electrospray Ionization Mass Spectrometry ◽  
Ionization Mass Spectrometry ◽  
Ionization Mass ◽  
Tandem Mass ◽  
Specific Interactions ◽  
Mass Spectrometry Application

The unique complexes of [2Dis + Leu + K]+ were discovered and successfully applied for the discrimination of twelve disaccharide isomers using tandem mass spectrometry in combination with statistical analysis.

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