Modulation of resistance to cisplatin by amphotericin B and aphidicolin in human larynx carcinoma cells

1995 ◽  
Vol 35 (4) ◽  
pp. 327-333 ◽  
Author(s):  
L. Beketic-Oreskovic ◽  
Maja Osmak
Keyword(s):  
Amphotericin B ◽  
Carcinoma Cells ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma

Hyperthermic modulation of resistance tocis-diammine-dichloroplatinum(II) in human larynx carcinoma cells

1997 ◽  
Vol 13 (2) ◽  
pp. 205-214 ◽  
Author(s):  
L. Beketić-Oreŝ Ković ◽  
M. Jakŝić ◽  
S. Oreŝković ◽  
M. Osmak
Keyword(s):  
Carcinoma Cells ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma

Characterization of carboplatin-resistant sublines derived from human larynx carcinoma cells

1995 ◽  
Vol 347 (3-4) ◽  
pp. 141-150 ◽  
Author(s):  
M. Osmak ◽  
L. Bizjak ◽  
B. Jernej ◽  
S. Kapitanović
Keyword(s):  
Carcinoma Cells ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma

scholarly journals Anti-proteasome autoantibodies contribute to anti-nuclear antibody patterns on human larynx carcinoma cells

2006 ◽  
Vol 66 (1) ◽  
pp. 5-11 ◽  
Author(s):  
E Feist ◽  
M Brychcy ◽  
G Hausdorf ◽  
B Hoyer ◽  
K Egerer ◽  
...  
Keyword(s):  
Carcinoma Cells ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Human Larynx Carcinoma

Combined Vitamins B12b and C Induce the Glutathione Depletion and the Death of Epidermoid Human Larynx Carcinoma Cells HEp-2

2000 ◽  
Vol 20 (5) ◽  
pp. 411-417 ◽  
Author(s):  
Vladimir S. Akatov ◽  
Yury V. Evtodienko ◽  
Violetta V. Leshchenko ◽  
Vera V. Teplova ◽  
Margarita M. Potselueva ◽  
...  
Keyword(s):  
Redox System ◽  
Carcinoma Cells ◽  
Glutathione Depletion ◽  
Cytotoxic Action ◽  
Glutathione Level ◽  
Human Larynx ◽  
Combined Action ◽  
Human Larynx Carcinoma ◽  
Preceding Cell

The combination of hydroxocobalamin (vitamin B12b) and ascorbicacid (vitamin C) can cause the death of tumor cells at the concentrationsof the components at which they are nontoxic when administeredseparately. This cytotoxic action on epidermoid human larynx carcinomacells HEp-2 in vitro is shown to be due to the hydrogen peroxidegenerated by the combination of vitamins B12b and C. The drop inthe glutathione level preceding cell death was found to be the result ofcombined action of the vitamins. It is supposed that the induction of celldeath by combined action of vitamins B12b and C is connected to the damageof the cell redox system.

scholarly journals Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid

2010 ◽  
Vol 6 ◽  
Author(s):  
Arne Homann ◽  
Riaz-ul Qamar ◽  
Sevnur Serim ◽  
Petra Dersch ◽  
Jürgen Seibel
Keyword(s):  
Sialic Acid ◽  
Cell Surface ◽  
Carcinoma Cell ◽  
Larynx Carcinoma ◽  
Interaction Processes ◽  
Acid Analogue ◽  
Human Larynx ◽  
Sialic Acid Analogue ◽  
Metabolic Glycoengineering ◽  
Human Larynx Carcinoma

Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of pathogens prior to infection and immunogenicity. Here we present the synthesis and bioorthogonal metabolic incorporation of the sialic acid analogue N-(1-oxohex-5-ynyl)neuraminic acid (Neu5Hex) into the cell-surface glycocalyx of a human larynx carcinoma cell line (HEp-2) and its fluorescence labelling by click chemistry.

scholarly journals Evaluation of Transfected HEP-2 Cell Line Using ß-Galactosidase Reporter Assay System

2011 ◽  
Vol 8 (3) ◽  
pp. 728-735
Author(s):  
Baghdad Science Journal
Keyword(s):  
Cell Line ◽  
High Efficiency ◽  
Carcinoma Cell ◽  
Transfection Efficiency ◽  
Carcinoma Cell Line ◽  
Larynx Carcinoma ◽  
Human Larynx ◽  
Therapy Studies ◽  
Human Larynx Carcinoma ◽  
Transfection Agent

Liposome-mediated transfection of cancer cells provide a valuable experimental technique to study cellular gene expression and may also be adapted for gene therapy studies. However, the widely recognized advantage of liposome-mediated transfection is high efficiency. Therefore, this study were performed to optimize transfection techniques in human larynx carcinoma cell line Hep-2 using the commercial synthetic lipid TransFast™ Reagent and monitoring the expression efficiency by using the pSV-?-galactosidase Control Vector which encoded ?-galactosidase, maximum transfection efficiency were achieved with TransFast™ Reagent used at the Charge ratios of 2:1 and 0.5 µg DNA/ml, this is indicate that TransFast™ Reagent can be used as an efficient transfection agent to deliver foreign DNA into human larynx carcinoma cell line Hep-2 and expression of the transgene efficiently.

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