Clinical significance of estrogen receptor β in breast cancer

2005 ◽  
Vol 56 (S1) ◽  
pp. 21-26 ◽  
Author(s):  
Shigehira Saji ◽  
Makiko Hirose ◽  
Masakazu Toi
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Clinical Significance ◽  
Estrogen Receptor Β

Clinical significance of estrogen receptor β in breast cancer

Breast Cancer ◽  
1999 ◽  
Vol 6 (4) ◽  
pp. 325-330 ◽  
Author(s):  
Hirotaka Iwase ◽  
Yoko Omoto ◽  
Tatsuya Toyama ◽  
Yasuo Hara ◽  
Hiroji Iwata ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Clinical Significance ◽  
Estrogen Receptor Β

scholarly journals Agonists and knockdown of estrogen receptor β differentially affect invasion of triple-negative breast cancer cells in vitro

BMC Cancer ◽  
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Susanne Schüler-Toprak ◽  
Julia Häring ◽  
Elisabeth C. Inwald ◽  
Christoph Moehle ◽  
Olaf Ortmann ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Triple Negative Breast Cancer ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
Estrogen Receptor Β

scholarly journals Expression of estrogen receptor β isoforms in normal breast epithelial cells and breast cancer: regulation by methylation

Oncogene ◽  
2003 ◽  
Vol 22 (48) ◽  
pp. 7600-7606 ◽  
Author(s):  
Chunyan Zhao ◽  
Eric W-F Lam ◽  
Andrew Sunters ◽  
Eva Enmark ◽  
Manuela Tamburo De Bella ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Epithelial Cells ◽  
Normal Breast ◽  
Estrogen Receptor Β ◽  
Breast Epithelial Cells ◽  
Breast Epithelial ◽  
Normal Breast Epithelial Cells

Clinical significance of estrogen receptor 1 gene mutations in hormonal resistant breast cancer patients

Gene Reports ◽  
2021 ◽  
pp. 101261
Author(s):  
Reham A. Aboelwafa ◽  
Nermine H. Zakaria ◽  
Neamat Hagazy ◽  
Inas I. Zaki ◽  
Aya S. Rady ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Gene Mutations ◽  
Breast Cancer Patients ◽  
Estrogen Receptor 1

Different associations of estrogen receptor β isoforms, ERβ1 and ERβ2, expression levels with tumor size and survival in early- and late-onset breast cancer

2012 ◽  
Vol 321 (1) ◽  
pp. 73-79 ◽  
Author(s):  
Vesna Mandusic ◽  
Bogomir Dimitrijevic ◽  
Dragica Nikolic-Vukosavljevic ◽  
Zora Neskovic-Konstantinovic ◽  
Ksenija Kanjer ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Tumor Size ◽  
Late Onset ◽  
Estrogen Receptor Β ◽  
Expression Levels

scholarly journals The expression and clinical significance of GADD45A in breast cancer patients

PeerJ ◽  
2018 ◽  
Vol 6 ◽  
pp. e5344 ◽  
Author(s):  
Junnan Wang ◽  
Yiran Wang ◽  
Fei Long ◽  
Fengshang Yan ◽  
Ning Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Patients ◽  
Clinical Significance ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Breast Cancer Patients ◽  
Ki 67 ◽  
Expression Levels ◽  
Cancer Tissues

BackgroundGrowth arrest and DNA-damage-inducible protein 45 alpha (GADD45A) was previously found to be associated with risk of several kinds of human tumors. Here, we studied the expression and clinical significance of GADD45A in breast cancer.MethodsWe performed an immunohistochemical study of GADD45A protein from 419 breast cancer tissues and 116 adjacent non-neoplastic tissues.ResultsSignificantly high GADD45A expression were observed in breast cancer tissues compared with adjacent non-neoplastic tissues (P < 0.001) and were independently correlative with estrogen receptor negative (P = 0.028) and high Ki-67 index (P < 0.001). Kaplan–Meier survival analysis revealed that patients with high GADD45A expression levels had a worse long-term prognosis in triple negative breast cancer (P = 0.041), but it was not an independent prognostic factor in multivariate analysis (P = 0.058).ConclusionsGADD45A expression levels are significantly correlative with estrogen receptor status and Ki-67 index in human breast cancer. Patients with triple negative breast cancer might be stratified into high risk and low risk groups based on the GADD45A expression levels.

Knockdown of PTEN decreases expression of estrogen receptor β and tamoxifen sensitivity of human breast cancer cells

Steroids ◽  
2020 ◽  
Vol 153 ◽  
pp. 108521
Author(s):  
Oliver Treeck ◽  
Susanne Schüler-Toprak ◽  
Maciej Skrzypczak ◽  
Florian Weber ◽  
Olaf Ortmann
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Cancer Cells ◽  
Human Breast Cancer ◽  
Breast Cancer Cells ◽  
Estrogen Receptor Β ◽  
Human Breast Cancer Cells ◽  
Human Breast ◽  
Tamoxifen Sensitivity

Phosphorylation of Estrogen Receptor β at Serine 105 in Primary Breast Cancer.

2009 ◽  
Author(s):  
W. Hamilton-Burke ◽  
A. Shaaban ◽  
M. Cummings ◽  
D. Holliday ◽  
S. Pollock ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Primary Breast Cancer ◽  
Estrogen Receptor Β
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