Thyroid Cancer in Patients with Familial Adenomatous Polyposis

1998 ◽  
Vol 22 (7) ◽  
pp. 738-743 ◽  
Author(s):  
Nancy D. Perrier ◽  
Jon A. van Heerden ◽  
John R. Goellner ◽  
E. Dillwyn Williams ◽  
Hossein Gharib ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis

Barriers to thyroid cancer screening with ultrasound in patients with familial adenomatous polyposis

2019 ◽  
Vol 129 (10) ◽  
pp. 2436-2441 ◽  
Author(s):  
Celeste Nagy ◽  
Zachary Kelly ◽  
Steven Keilin ◽  
Field Willingham ◽  
Amy Chen
Keyword(s):  
Thyroid Cancer ◽  
Cancer Screening ◽  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis ◽  
Thyroid Cancer Screening

scholarly journals Age- and Gender-Specific Risk of Thyroid Cancer in Patients With Familial Adenomatous Polyposis

2016 ◽  
Vol 101 (12) ◽  
pp. 4611-4617 ◽  
Author(s):  
Shinya Uchino ◽  
Hideki Ishikawa ◽  
Akira Miyauchi ◽  
Mitsuyoshi Hirokawa ◽  
Shiro Noguchi ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Thyroid Nodules ◽  
Adenomatous Polyposis ◽  
Protein Truncation Test ◽  
Exact Test ◽  
Female Patients ◽  
And Gender ◽  
Transducer Probe ◽  
Gender Specific

Context: The cribriform-morula variant of papillary thyroid carcinoma (CMV-PTC) is a rare variant of PTC and is associated with familial adenomatous polyposis (FAP). However, the incidence and the nature of CMV-PTC among FAP patients have not been well characterized. Objective: The aim of this study was to determine the incidence and characteristics of thyroid cancer screened by neck ultrasonography for FAP patients. Design, Patients, and Intervention: A total of 129 FAP patients were included in this study. Neck ultrasonography was performed using a 12.0-MHz transducer probe. Germline APC gene mutation was examined for by the protein truncation test or DNA sequencing methods. Results: Twenty-one patients (16.3%) had solid nodules, and 24 patients (18.6%) had benign cystic nodules. In total, PTC was found in 11 patients (16% of the women and 0% of the men), 8 of which were CMV-PTC and the rest were classical PTC. In 17 female patients with thyroid nodules, CMV-PTC occurred in 8 of 9 patients who were 35 years age or younger but in none of the 8 patients who were older than 35 (P = .0004 by Fisher’s exact test). The APC germline mutations in 8 patients with CMV-PTC were present at the 5′ side of the profuse type of FAP region (codons 1249–1330). Conclusions: The prevalence of CMV-PTC in FAP patients was higher than previously reported and this type of tumor was found preferentially in younger (under age 35) female patients with FAP in this cohort.

scholarly journals Cribiform variant of papillary thyroid cancer and familial adenomatous polyposis

2015 ◽  
Vol 16 ◽  
pp. 192-194 ◽  
Author(s):  
E. Perea del Pozo ◽  
C. Ramirez Plaza ◽  
J. Padillo Ruiz ◽  
J.M. Martos Martínez
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Papillary Thyroid Cancer ◽  
Adenomatous Polyposis ◽  
Papillary Thyroid

Screening for Thyroid Cancer in Patients With Familial Adenomatous Polyposis

2011 ◽  
Vol 253 (3) ◽  
pp. 515-521 ◽  
Author(s):  
Awad M. Jarrar ◽  
Mira Milas ◽  
Jamie Mitchell ◽  
Lisa Laguardia ◽  
Margaret ([a-z]+)ʼMalley ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis

scholarly journals Association between thyroid cancer of cribriform variant and familial adenomatous polyposis.

1996 ◽  
Vol 49 (7) ◽  
pp. 611-613 ◽  
Author(s):  
K Hizawa ◽  
M Iida ◽  
T Yao ◽  
K Aoyagi ◽  
Y Oohata ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis

Screening for Thyroid Cancer in Patients With Familial Adenomatous Polyposis

2015 ◽  
Vol 261 (1) ◽  
pp. e13-e14 ◽  
Author(s):  
Francesco Cetta ◽  
Gabriele Ugolini ◽  
Jacopo Martellucci ◽  
Giuseppe Gotti
Keyword(s):  
Thyroid Cancer ◽  
Familial Adenomatous Polyposis ◽  
Adenomatous Polyposis

scholarly journals Thyroid cancer in Gardner’s syndrome: Case report and review of literature

2012 ◽  
Vol 01 (01) ◽  
pp. 43-47 ◽  
Author(s):  
Sachin B. Punatar ◽  
Vanita Noronha ◽  
Amit Joshi ◽  
Kumar Prabhash
Keyword(s):  
Thyroid Cancer ◽  
Case Report ◽  
Familial Adenomatous Polyposis ◽  
Male Patient ◽  
Gardner's Syndrome ◽  
Endocrine Tumors ◽  
Adenomatous Polyposis ◽  
Review Of Literature ◽  
Gardner’S Syndrome

AbstractGardner′s syndrome is a variant of familial adenomatous polyposis. A multitude of extra-colonic manifestations including various endocrine tumors have been associated with this syndrome, the commonest of which is thyroid cancer. Majority of the patients with thyroid cancer and Gardner′s syndrome are females. Here we describe a male patient with Gardner′s syndrome who subsequently developed thyroid cancer.

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