scholarly journals The prognostic significance of DNA cytophotometry and proliferation index (Ki-67) in giant cell tumors of bone

1999 ◽  
Vol 23 (6) ◽  
pp. 315-319 ◽  
Author(s):  
I. Antal ◽  
Z. S�pi ◽  
M. Szendr�i
Keyword(s):  
Giant Cell ◽  
Prognostic Significance ◽  
Proliferation Index ◽  
Giant Cell Tumors ◽  
Ki 67 ◽  
Dna Cytophotometry ◽  
Tumors Of Bone

scholarly journals Proliferation index and vascular density of giant cell tumors of bone: Are they prognostic markers?

Cancer ◽  
1996 ◽  
Vol 77 (10) ◽  
pp. 2044-2051 ◽  
Author(s):  
Muhammadsamir A. Sulh ◽  
M. Alba Greco ◽  
Tony Jiang ◽  
Sunanda B. Goswami ◽  
David Present ◽  
...  
Keyword(s):  
Giant Cell ◽  
Prognostic Markers ◽  
Proliferation Index ◽  
Vascular Density ◽  
Giant Cell Tumors ◽  
Tumors Of Bone

Giant Cell Tumor of the Talar Neck

2007 ◽  
Vol 97 (3) ◽  
pp. 225-228 ◽  
Author(s):  
Hakan Selek ◽  
Hamza Özer ◽  
Sacit Turanli ◽  
Özlem Erdem
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Clinical Signs ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Radiographic Appearance ◽  
Aneurysmal Bone Cysts ◽  
Tumors Of Bone ◽  
Brown Tumors ◽  
Small Bones

We describe a patient with a giant cell tumor in the talar head and neck of the left foot who was diagnosed as having osteochondritis dissecans and treated with arthroscopic drilling in this same location 3 years earlier. Giant cell tumors can be confused with several conditions, including giant cell reparative granulomas, brown tumors, and aneurysmal bone cysts. Giant cell tumors of bone typically occur in the epiphysis of long bones, including the distal femur and proximal tibia. They are uncommonly found in the small bones of the foot or ankle, and talar involvement is rare. Despite this rarity, the radiographic appearance and clinical signs of talar lesions should be considered in the differential diagnosis of nontraumatic conditions in the foot. (J Am Podiatr Med Assoc 97(3): 225–228, 2007)

scholarly journals Protein Expression Profiling of Giant Cell Tumors of Bone Treated with Denosumab

PLoS ONE ◽  
2016 ◽  
Vol 11 (2) ◽  
pp. e0148401 ◽  
Author(s):  
Kenta Mukaihara ◽  
Yoshiyuki Suehara ◽  
Shinji Kohsaka ◽  
Keisuke Akaike ◽  
Yu Tanabe ◽  
...  
Keyword(s):  
Protein Expression ◽  
Giant Cell ◽  
Expression Profiling ◽  
Giant Cell Tumors ◽  
Tumors Of Bone

Giant-Cell Tumors of Bone and Progesterone Receptors

Orthopedics ◽  
2003 ◽  
Vol 26 (12) ◽  
pp. 1209-1212
Author(s):  
Nikolaos Demertzis ◽  
Fani Kotsiandri ◽  
Ioulia Giotis ◽  
Nikiphoros Apostolikas
Keyword(s):  
Giant Cell ◽  
Progesterone Receptors ◽  
Giant Cell Tumors ◽  
Tumors Of Bone

scholarly journals Correlation between Campanacci’s radiological classification of giant cell tumor of bone and expression of Cyclin D1 and PCNA

2017 ◽  
Vol 7 (1) ◽  
pp. 47
Author(s):  
Eréndira G. Estrada-Villaseñor ◽  
Hidalgo Bravo Alberto ◽  
C. Bandala ◽  
P. De la Garza-Montano ◽  
Reyes Medina Naxieli ◽  
...  
Keyword(s):  
Cyclin D1 ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Descriptive Study ◽  
Cell Tumor ◽  
Giant Cell Tumors ◽  
Radiological Classification ◽  
Tumors Of Bone ◽  
Made In

Giant cell tumor of bone is considered by his behavior a benign but aggressive neoplasm. The objective of our study was to determine if there is a correlation between the Campanacci’s radiological classification of giant cell tumors of bone and the expression by immunohistochemistry of Cyclin D1 and proliferation cell nuclear antibody (PCNA). A retrospective and descriptive study was made. In total, there were 27 cases. All cases showed Cyclin D1 and PCNA positivity. Rho Spearman for Campanacci and Cyclin D1 expression was 0.06 and for Campanacci and PCNA was 0.418. We conclude that there is a positive correlation between PCNA expression in giant cell tumors of Bone and the Campanacci’s radiological classification II and III, butCyclin D1 expression was no related with radiologic features.

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