Optimization of X-ray mammography and technetium-99m methoxyisobutylisonitrile scintimammography in the diagnosis of non-palpable breast lesions

1998 ◽  
Vol 25 (5) ◽  
pp. 491-496 ◽  
Author(s):  
Isabel Uriarte ◽  
Jose Manuel Carril ◽  
Remedios Quirce ◽  
Ceferino Gutiérrez-Mendiguchí ◽  
Isabel Blanco ◽  
...  
Keyword(s):  
Breast Lesions ◽  
X Ray ◽  
Technetium 99M ◽  
Palpable Breast ◽  
Technetium 99M Methoxyisobutylisonitrile

scholarly journals X-ray and Ultrasound Localization of Non-Palpable Breast Lesions and Difficulties in Management

1987 ◽  
Vol 80 (11) ◽  
pp. 678-680 ◽  
Author(s):  
J J T Tate ◽  
G T Royle ◽  
P McDonald ◽  
P B Guyer ◽  
I Taylor
Keyword(s):  
Breast Lesion ◽  
Careful Examination ◽  
Breast Lesions ◽  
Residual Cancer ◽  
X Ray ◽  
Ultrasound Localization ◽  
Biopsy Site ◽  
Operative Specimen ◽  
Asymptomatic Patients ◽  
Palpable Breast

Seventy-four patients who have had biopsy of a non-palpable breast lesion are reviewed. A double-dye localization technique was used in 88% while in 12% localization of the lesion was best achieved by ultrasound mammography. Biopsy was successful in 70 patients (95%) at the first attempt. The overall incidence of malignancy was 20%, being greater in asymptomatic patients (32%) than in patients with mastalagia (16%). Re-excision of the biopsy site in these patients showed residual cancer in 33%. It is suggested that both careful examination of the operative specimen and postoperative mammography may be necessary to ensure that the original lesion has been removed. Re-excision of the biopsy site appears to be necessary when the histology is malignant.

99MTechnetium-sestamibi scintimammography in non-palpable breast lesions found on screening X-ray mammography

2007 ◽  
Vol 33 (1) ◽  
pp. 23-27 ◽  
Author(s):  
G.M.M. Gommans ◽  
F.M. van der Zant ◽  
A. van Dongen ◽  
R.O. Boer ◽  
G.J.J. Teule ◽  
...  
Keyword(s):  
Breast Lesions ◽  
X Ray ◽  
Palpable Breast

201Tl Scintigraphy in the Evaluation of Palpable and Nonpalpable Breast Lesions: Correlation with Mammography and Ultrasonography

1997 ◽  
Vol 36 (08) ◽  
pp. 282-288 ◽  
Author(s):  
T. Atasever ◽  
A. Özdemir ◽  
I. Öznur ◽  
N. I. Karabacak ◽  
N. Gökçora ◽  
...  
Keyword(s):  
Final Diagnosis ◽  
Lower Sensitivity ◽  
Breast Lesions ◽  
Breast Cancers ◽  
Combined Use ◽  
Malignant Breast ◽  
Malignant Lesions ◽  
Benign Breast Lesions ◽  
Palpable Breast ◽  
Metastatic Sites

Summary Aim: Our goal was to determine the clinical usefulness of TI-201 to identify breast cancer in patients with suspicious breast lesions on clinical examination, and/or abnormal radiologic (mammography and/or ultrasonography) findings. Methods: TI-201 scintigraphy were performed in sixty-eight patients with 70 breast abnormalities (51 palpable, 19 nonpalpable) and compared with mammography and ultrasonography (US). Early (15 min) and late (3 h) images of the breasts were obtained following the injection of 111 MBq (3 mCi) of TI-201. Visual and semiquantitative interpretation was performed. Results: Final diagnosis confirmed 52 malignant breast lesions and 18 benign conditions. TI-201 visualized 47 of 52 (90%) overall malignant lesions. Thirty-eight of 40 (95%) palpable and 9 of 12 (75%) nonpalpable breast cancers were detected by TI-201 scintigraphy. The smallest mass lesion detected by TI-201 measured 1.5x1.0 cm. Eleven breast lesions were interpreted as indeterminate by mammography and/or sonography. TI-201 scintigraphy excluded malignancy in 7 of 8 (88%) patients with benign breast lesions interpreted as indeterminate. Five of the 18 (28%) benign breast lesions showed TI-201 uptake. None of the fibroadenoma and fibrocystic changes accumulated TI-201. TI-201 scintigraphy, mammography and ultrasonography showed 90%, 92%, 85% overall sensitivity and 72%, 56%, 61% overall specificity respectively. Twenty-one of the 28 (75%) axillary nodal metastatic sites were also detected by TI-201. In malignant and benign lesions, early and late lesion/contralateral normal side (L/N) ratios were 1.58 ± 0.38 (mean ± SD) and 1.48 ± 0.32 (p >0.05), 1.87 ± 0.65 and 1.34 ± 0.20 (p<0.05) respectively. The mean early and late L/N ratios of malignant and benign groups did not show statistical difference (p>0.05). Conclusion: Overall, TI-201 scintigraphy was the most specific of the three methods and yielded favourable results in palpable breast cancers, while it showed lower sensitivity in nonpalpable cancers and axillary metastases. Combined use of TI-201 scintigraphy with mammography and US seems to be useful in difficult cases, such as dense breasts and indeterminate breast lesions.

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