scholarly journals Retardation of myelination due to dietary vitamin B12 deficiency: cranial MRI findings

1997 ◽  
Vol 27 (2) ◽  
pp. 155-158 ◽  
Author(s):  
Karl-Olof Lövblad ◽  
Gianpaolo Ramelli ◽  
Luca Remonda ◽  
Arto C. Nirkko ◽  
Christoph Ozdoba ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
Mri Findings ◽  
Cranial Mri ◽  
B12 Deficiency

scholarly journals Reversible ecchymosis and hyperpigmented lesions: A rare presentation of dietary Vitamin B12 deficiency

2016 ◽  
Vol 5 (2) ◽  
pp. 485 ◽  
Author(s):  
HansRaj Pahadiya ◽  
Manoj Lakhotia ◽  
Sukhdev Choudhary ◽  
GopalRaj Prajapati ◽  
Sangeeta Pradhan
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
Rare Presentation ◽  
B12 Deficiency

scholarly journals Dietary vitamin B12 deficiency in an adolescent white boy

2002 ◽  
Vol 55 (6) ◽  
pp. 475-476 ◽  
Author(s):  
P O'Gorman ◽  
D Holmes ◽  
A V Ramanan ◽  
B Bose-Haider ◽  
M J Lewis ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
B12 Deficiency

scholarly journals Holotranscobalamin as an Indicator of Dietary Vitamin B12 Deficiency

2003 ◽  
Vol 49 (12) ◽  
pp. 2076-2078 ◽  
Author(s):  
Zouë Lloyd-Wright ◽  
Anne-Mette Hvas ◽  
Jan Møller ◽  
Tom A B Sanders ◽  
Ebba Nexø
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
B12 Deficiency

scholarly journals Subacute Combined Degeneration of the Spinal Cord due to Different Etiologies and Improvement of MRI Findings

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Azize Esra Gürsoy ◽  
Mehmet Kolukısa ◽  
Gülsen Babacan-Yıldız ◽  
Arif Çelebi
Keyword(s):  
Spinal Cord ◽  
Nitrous Oxide ◽  
Vitamin B12 ◽  
Neurological Complication ◽  
Vitamin B12 Deficiency ◽  
Vegetarian Diet ◽  
Mri Findings ◽  
Subacute Combined Degeneration ◽  
B12 Deficiency ◽  
Reversible Condition

Subacute combined degeneration (SCD) is a rare neurological complication of vitamin B12 deficiency, characterized by demyelination of the dorsal and lateral spinal cord. Herein, we describe three cases, who presented with SCD, one related to reduced intake of vitamin B12 because of a vegetarian diet and two related to nitrous oxide exposure during surgery. MR images of our patients revealed symmetrical hyperintense signals in dorsal and lateral columns in T2 weighted series. After treatment with intramuscular B12 injections (1 mg daily for 2 weeks, once weekly thereafter for three months) all patients showed improvement of their symptoms. Abnormalities of the spinal cord on MRI resolved in three months. In conclusion, SCD either due to nitrous oxide exposure or due to reduced intake of vitamin B12 is a reversible condition, when detected and treated early.

scholarly journals Dietary Intake and Status of Vitamin B12 in Slovenian Population

Nutrients ◽  
2022 ◽  
Vol 14 (2) ◽  
pp. 334
Author(s):  
Živa Lavriša ◽  
Hristo Hristov ◽  
Maša Hribar ◽  
Katja Žmitek ◽  
Anita Kušar ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Age Groups ◽  
Serum Vitamin ◽  
Vitamin B12 Deficiency ◽  
High Serum ◽  
Health Concern ◽  
Dietary Vitamin ◽  
Serum Homocysteine ◽  
Daily Vitamin ◽  
B12 Deficiency

Vitamin B12 deficiency poses a health concern, especially in vulnerable populations. Dietary vitamin B12 intake was obtained by two 24 h dietary recalls and food propensity questionnaires in a representative Slovenian cross-sectional food consumption survey, SI.Menu (n = 1248 subjects; 10–74 years). For a subgroup of 280 participants, data on serum vitamin B12 were available through the Nutrihealth study. The estimated usual population-weighted mean daily vitamin B12 intakes were 6.2 µg (adults), 5.4. µg (adolescents), and 5.0 µg (elderly). Lower intakes were observed in females. Inadequate daily vitamin B12 intake (<4 µg) was detected in 37.3% of adolescents, 31.7% of adults, and 58.3% elderlies. The significant predictors for inadequate daily vitamin B12 intake were physical activity score in all age groups, sex in adolescents and adults, financial status and smoking in elderly, and employment in adults. Meat (products), followed by milk (products), made the highest vitamin B12 contribution in all age groups. In adolescents, another important vitamin B12 contributor was cereals. The mean population-weighted serum vitamin B12 levels were 322.1 pmol/L (adults) and 287.3 pmol/L (elderly). Low serum vitamin B12 concentration (<148 nmol/L) and high serum homocysteine (>15 µmol/L) were used as criteria for vitamin B12 deficiency. The highest deficiency prevalence was found in elderlies (7.0%), particularly in males (7.9%). Factors associated with high serum homocysteine were also investigated. In conclusion, although vitamin B12 status was generally not critical, additional attention should be focused particularly to the elderly.

scholarly journals Low vitamin B12 diet increases liver homocysteine levels and leads to liver steatosis in rats

2019 ◽  
Vol 38 (3) ◽  
pp. 194
Author(s):  
Imelda Rosalyn Sianipar ◽  
Irena Ujianti ◽  
Sophie Yolanda ◽  
Ahmad Aulia Jusuf ◽  
Neng Tine Kartinah ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Vitamin B12 ◽  
Insulin Signaling ◽  
Liver Steatosis ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
Control Group ◽  
Treatment Groups ◽  
Treatment Standard ◽  
B12 Deficiency

Background <br />Nonalcoholic fatty liver disease (NAFLD) is one of the most widespread chronic liver diseases, caused by the development of insulin resistance. One of the mechanisms involved is a disturbance in insulin signaling by certain toxic substances that interact with one of the proteins responsible for the insulin signaling pathway. Increased homocysteine level, upon disruption of the methionine pathway, is associated with insulin resistance. The aim of this study was to evaluate the effect of hyperhomocysteinemia and insulin resistance (HOMA-IR level) induced by dietary vitamin B12 restriction on liver steatosis. <br /><br />Methods <br />A study of laboratory experimental design was conducted involving 18 male Sprague Dawley rats (age 36-40 weeks, BW 300-350 g), that were randomly divided into 3 groups: control, 8-week treatment, and 16-week treatment. Standard AIN-93 diet was administered to the control group, whereas rats in the treatment groups were fed vitamin B12 deficiency-AIN-93M. At the end of treatment, liver homocysteine levels were determined by ELISA, HOMA-IR values were calculated, and steatosis degree of the liver was determined histologically. Statistical analysis was performed using independent t-test. <br /><br />Results <br />A significant increase in liver homocysteine levels was found between the control and both the 8- and 16-week treatment groups (p&lt;0.001). HOMA-IR levels were significantly higher in both treatment groups compared to controls (p&lt;0.001). The area of liver steatosis in both treatment groups was significantly larger than that of the control group (p&lt;0.001). <br /><br />Conclusion <br />Increased homocysteine levels due to dietary vitamin B12 deficiency induces liver steatosis due to insulin resistance in rats.

scholarly journals Dietary Vitamin B12 Deficiency

1984 ◽  
Vol 145 (6) ◽  
pp. 671-671 ◽  
Author(s):  
Frank Rawlinson ◽  
John M. Eagles
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Dietary Vitamin ◽  
B12 Deficiency

The effects of dietary vitamin B12 deficiency on sperm maturation in developing and growing male rats

2003 ◽  
Vol 43 (1) ◽  
pp. 57-64 ◽  
Author(s):  
Toshiaki Watanabe ◽  
Keiko Ohkawa ◽  
Shigenobu Kasai ◽  
Shuhei Ebara ◽  
Yoshihisa Nakano ◽  
...  
Keyword(s):  
Vitamin B12 ◽  
Vitamin B12 Deficiency ◽  
Sperm Maturation ◽  
Male Rats ◽  
Dietary Vitamin ◽  
B12 Deficiency
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