Suprasellar seeding of a benign choroid plexus papilloma of the fourth ventricle with local recurrence

2000 ◽  
Vol 42 (9) ◽  
pp. 657-661 ◽  
Author(s):  
M. Irsutti ◽  
M. Thorn-Kany ◽  
P. Arrué ◽  
J. Richaud ◽  
J. C. Sol ◽  
...  
Keyword(s):  
Local Recurrence ◽  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Plexus Papilloma

Ossified choroid plexus papilloma of the fourth ventricle: elucidation of the mechanism of osteogenesis in benign brain tumors

2013 ◽  
Vol 12 (1) ◽  
pp. 13-20 ◽  
Author(s):  
Sunil Manjila ◽  
Erin Miller ◽  
Amad Awadallah ◽  
Shunichi Murakami ◽  
Mark L. Cohen ◽  
...  
Keyword(s):  
Brain Tumors ◽  
Bone Formation ◽  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Immunohistochemical Analysis ◽  
Pluripotent Cell ◽  
Bone Trabeculae ◽  
Plexus Papilloma ◽  
Mature Bone

True ossification within benign brain tumors is rare, and the molecular mechanism for this process is poorly understood. The authors report a case of ossified choroid plexus papilloma (CPP) and analyze it to help elucidate the underlying molecular basis of osteogenesis in benign brain tumors. A 21-year-old man presented with headache and depression that progressed over years. Computed tomography, MRI, and angiography demonstrated a large heavily calcified fourth ventricular tumor with a vascular blush and no hydrocephalus. The tumor was resected and was found to be an ossified CPP. Immunohistochemical staining for VEGF, Sox2, BMP-2, osterix, osteopontin, and osteocalcin was performed in an attempt to elucidate the mechanism of bone formation. The tumor was extensively ossified with mature bone trabeculae. Immunostaining for VEGF was positive. Additional staining showed the presence of osteocalcin in this ossified tumor but not in samples of nonossified CPPs collected from other patients. Staining for osterix and osteopontin was equivocally positive in the ossified CPP but also in the nonossified CPPs examined. The presence of osteocalcin in the ossified CPP demonstrates that there is true bone formation rather than simple calcification. Its appearance within cells around the trabeculae suggests the presence of osteoblasts. The presence of osterix suggests that a pluripotent cell, or one that is already partially differentiated, may be differentiated into an osteoblast through this pathway. This represents the first systematic immunohistochemical analysis of osteogenesis within choroid plexus tumors.

Akinetic mutism after fourth ventricle choroid plexus papilloma: treatment with a dopamine agonist

1999 ◽  
Vol 51 (2) ◽  
pp. 181-184 ◽  
Author(s):  
Hakan Caner ◽  
Nur Altinörs ◽  
Sibel Benli ◽  
Tarkan Çalişaneller ◽  
Ahmet Albayrak
Keyword(s):  
Dopamine Agonist ◽  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Akinetic Mutism ◽  
Plexus Papilloma

Diffuse craniospinal seeding from a benign fourth ventricle choroid plexus papilloma

1998 ◽  
Vol 88 (4) ◽  
pp. 757-760 ◽  
Author(s):  
Richard Leblanc ◽  
Sabah Bekhor ◽  
Denis Melanson ◽  
Stirling Carpenter
Keyword(s):  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Obstructive Hydrocephalus ◽  
Choroid Plexus Papilloma ◽  
Blurred Vision ◽  
Content Type ◽  
Biological Potential ◽  
History Of ◽  
Fine Print ◽  
Plexus Papilloma

✓ Choroid plexus papillomas can metastasize to the subarachnoid space, but extensive metastasis has only been reported when the tumors are malignant. The authors report a case of diffuse, extensive metastasis to the craniospinal leptomeninges from a benign fourth ventricular choroid plexus papilloma in an adult. This 19-year-old woman presented with a 2-year history of headache, blurred vision, diplopia, and ataxia. Magnetic resonance imaging of the brain and spinal cord revealed obstructive hydrocephalus caused by a 4-cm, partially calcified, inhomogeneously enhancing tumor of the fourth ventricle that was displacing the pons, medulla oblongata, and cerebellum. Innumerable cystic lesions of varying size were also seen in the cranial and spinal leptomeninges. Histological examination of the resected fourth ventricular tumor and of a few of the leptomeningeal lesions revealed a benign choroid plexus papilloma and leptomeningeal choroid plexus cysts. This singular case of diffuse and extensive metastasis to the craniospinal leptomeninges from a histologically benign fourth ventricular papilloma adds to the available information about the biological potential of these tumors and expands the differential diagnosis of posterior fossa lesions with subarachnoid metastasis.

Early Second-Trimester Spontaneous Miscarriage Due to Fourth Ventricle Choroid Plexus Papilloma

2018 ◽  
Vol 5 (3) ◽  
pp. 163-165
Author(s):  
George S. Stoyanov ◽  
Ina Kobakova ◽  
Dimo Stoyanov ◽  
Marin Zhelezov ◽  
Meglena Angelova ◽  
...  
Keyword(s):  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Second Trimester ◽  
Spontaneous Miscarriage ◽  
Plexus Papilloma

scholarly journals Fourth ventricle primitive choroid plexus papilloma with divergent differentiation potentials: a case report

2015 ◽  
Vol 2 (4) ◽  
Author(s):  
Rosalba Vega-Orozco ◽  
Martha Lilia Tena-Suck ◽  
Daniel Rembao Bojórquez ◽  
Miguel Ángel Collado-Ortiz
Keyword(s):  
Case Report ◽  
Choroid Plexus ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Divergent Differentiation ◽  
Plexus Papilloma

scholarly journals Choroid plexus papilloma of the fourth ventricle in a septuagenarian

2012 ◽  
Vol 03 (03) ◽  
pp. 402-404
Author(s):  
Alok A. Umredkar ◽  
Rajesh Chhabra ◽  
Aman Bal ◽  
Ashim Das
Keyword(s):  
Choroid Plexus ◽  
Posterior Fossa ◽  
Fourth Ventricle ◽  
Choroid Plexus Papilloma ◽  
Provisional Diagnosis ◽  
Geriatric Population ◽  
Choroid Plexus Papillomas ◽  
Plexus Papilloma ◽  
Posterior Fossa Lesion

ABSTRACTChoroid plexus papillomas (CPP) are most commonly found in children and rarely in adult. A very few cases are reported in geriatric population. We present a case of 72-year-old man with posterior fossa lesion operated with provisional diagnosis of metastasis, but turn out to be CPP.

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