Localisation and surface quantification of secondary metabolites in the red alga Delisea pulchra

1999 ◽  
Vol 133 (4) ◽  
pp. 727-736 ◽  
Author(s):  
S. A. Dworjanyn ◽  
R. De Nys ◽  
P. D. Steinberg
Keyword(s):  
Secondary Metabolites ◽  
Red Alga ◽  
Delisea Pulchra

scholarly journals Chemical mediation of bacterial surface colonisation by secondary metabolites from the red alga Delisea pulchra

1998 ◽  
Vol 15 ◽  
pp. 233-246 ◽  
Author(s):  
R Maximilien ◽  
R de Nys ◽  
C Holmström ◽  
L Gram ◽  
M Givskov ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Red Alga ◽  
Bacterial Surface ◽  
Chemical Mediation ◽  
Delisea Pulchra

scholarly journals Traffic of Secondary Metabolites to Cell Surface in the Red Alga Laurencia dendroidea Depends on a Two-Step Transport by the Cytoskeleton

PLoS ONE ◽  
2013 ◽  
Vol 8 (5) ◽  
pp. e63929 ◽  
Author(s):  
Vanessa M. Reis ◽  
Louisi S. Oliveira ◽  
Raoni M. F. Passos ◽  
Nathan B. Viana ◽  
Cláudia Mermelstein ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Cell Surface ◽  
Red Alga

scholarly journals Genomes and Virulence Factors of Novel Bacterial Pathogens Causing Bleaching Disease in the Marine Red Alga Delisea pulchra

PLoS ONE ◽  
2011 ◽  
Vol 6 (12) ◽  
pp. e27387 ◽  
Author(s):  
Neil Fernandes ◽  
Rebecca J. Case ◽  
Sharon R. Longford ◽  
Mohammad R. Seyedsayamdost ◽  
Peter D. Steinberg ◽  
...  
Keyword(s):  
Virulence Factors ◽  
Bacterial Pathogens ◽  
Red Alga ◽  
Delisea Pulchra

New Bioactive Secondary Metabolites from Bornean Red Alga, Laurencia similis (Ceramiales)

2013 ◽  
Vol 8 (3) ◽  
pp. 1934578X1300800 ◽  
Author(s):  
Takashi Kamada ◽  
Charles Santhanaraju Vairappan
Keyword(s):  
Antibacterial Activity ◽  
Secondary Metabolites ◽  
Secondary Metabolite ◽  
Red Alga ◽  
Algal Population ◽  
Cytotoxic Effects ◽  
Antibiotic Resistant ◽  
Good Antibacterial Activity ◽  
Bioactive Secondary Metabolites ◽  
Red Algal

A Bornean red algal population of Laurencia simlis Nam et Saito was analyzed for its secondary metabolite composition. Seven compounds were identified: ent -1(10)-aristolen-9β-ol (1), (+)-aristolone (2), axinysone B (3), 9-aristolen-1α-ol (4), 2,3,5,6-tetrabromoindole (5), 1-methyl-2,3,5,6-tetrabromoindole (6), and 1-methyl-2,3,5-tribromoindole (7). Compound 1 was identified as a new optical isomer of 1(10)-aristolen-9β-ol. Compounds 1, 4 and 5 exhibited good antibacterial activity against antibiotic resistant clinical bacteria and cytotoxic effects against selected cancer cell lines.

Polyhalogenated Indoles from the Red Alga Rhodophyllis membranacea: The First Isolation of Bromo-Chloro-Iodo Secondary Metabolites

2016 ◽  
Vol 79 (3) ◽  
pp. 463-469 ◽  
Author(s):  
Victoria H. Woolner ◽  
Cori M. Jones ◽  
Jessica J. Field ◽  
Nazmi H. Fadzilah ◽  
Andrew B. Munkacsi ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Red Alga

scholarly journals New Halogenated Secondary Metabolites from Red Algae of the South Pacific

2021 ◽  
Author(s):  
◽  
Victoria Woolner
Keyword(s):  
New Zealand ◽  
Secondary Metabolites ◽  
Structure Elucidation ◽  
Detailed Examination ◽  
Red Alga ◽  
Marine Natural Product ◽  
Extensive Investigation ◽  
Ic50 Value ◽  
Mass Spectrometric Evidence ◽  
Related Compounds

<p>An NMR- and MS-directed study led to the isolation and structure elucidation of several halogenated secondary metabolites from a New Zealand and a Tongan red alga. An extensive investigation was carried out on the New Zealand red alga Rhodophyllis membranacea following mass spectrometric evidence for an unusual tetrahalogenated indole with the exceptionally rare inclusion of bromine, chlorine and iodine within a fraction of a semi-purified extract. Due to the difficulty associated with the structure elucidation of proton deficient molecules, a strategic isolation and structure elucidation of several polyhalogenated indoles was employed in order to unequivocally assign the halogen positions on the indolic core. This resulted in the isolation and characterisation of 11 new tetrahalogenated indoles (123–133), four of which contain bromine, chlorine and iodine (124 and 129–131) and represent the first isolation of such compounds. Additionally, four new pentahalogenated indoles (134–137) and an uncharacterised tribromotrichloroindole were isolated. The synthetically known compound 4-chloroisatin (138) was isolated as a new marine natural product, while 4-chloro-3-hydroxyl-3-(2-oxopropyl)-2-oxindole (139) was established to be an artefact of isolation. Several compounds were found to exhibit antifungal properties against Saccharomyces cerevisiae.  A detailed examination of the Tongan alga Callophycus serratus led to the isolation of six new meroditerpenoids: callophycol C (227), iodocallophycols E (228) and F (229), iodocallophycoic acid B (230), deiodocallophycoic B (231) and callophycoic acid I (232). The relative configurations in compounds 228–231 are proposed to differ from closely related compounds in the literature. Iodocallophycol E (228) exhibited moderate cytotoxicity against the HL-60 cell line with an IC50 value of 6.0 μM.</p>

scholarly journals Quantitative variation of secondary metabolites in the sea hare Aplysia parvula and its host plant, Delisea pulchra

1996 ◽  
Vol 130 ◽  
pp. 135-146 ◽  
Author(s):  
R de Nys ◽  
PD Steinberg ◽  
CN Rogers ◽  
TS Charlton ◽  
MW Duncan
Keyword(s):  
Secondary Metabolites ◽  
Host Plant ◽  
Quantitative Variation ◽  
Sea Hare ◽  
Delisea Pulchra

scholarly journals Antifouling Activity of Halogenated Compounds Derived from the Red Alga Sphaerococcus coronopifolius: Potential for the Development of Environmentally Friendly Solutions

Marine Drugs ◽  
2021 ◽  
Vol 20 (1) ◽  
pp. 32
Author(s):  
Maxence Quémener ◽  
Stefanos Kikionis ◽  
Marilyne Fauchon ◽  
Yannick Toueix ◽  
Fanny Aulanier ◽  
...  
Keyword(s):  
Secondary Metabolites ◽  
Green Chemistry ◽  
Red Alga ◽  
Point Of View ◽  
Economic Losses ◽  
Research Strategies ◽  
Antifouling Paints ◽  
Antifouling Activity ◽  
Bioactive Secondary Metabolites ◽  
Adhesion Process

Nowadays, biofouling is responsible for enormous economic losses in the maritime sector, and its treatment with conventional antifouling paints is causing significant problems to the environment. Biomimetism and green chemistry approaches are very promising research strategies for the discovery of new antifouling compounds. This study focused on the red alga Sphaerococcus coronopifolius, which is known as a producer of bioactive secondary metabolites. Fifteen compounds, including bromosphaerol (1), were tested against key marine biofoulers (five marine bacteria and three microalgae) and two enzymes associated with the adhesion process in macroalgae and invertebrates. Each metabolite presented antifouling activity against at least one organism/enzyme. This investigation also revealed that two compounds, sphaerococcinol A (4) and 14R-hydroxy-13,14-dihydro-sphaerococcinol A (5), were the most potent compounds without toxicity towards oyster larvae used as non-target organisms. These compounds are of high potential as they are active towards key biofoulers and could be produced by a cultivable alga, a fact that is important from the green chemistry point of view.

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