Characterization of Matrix-Induced Osteogenesis in Rat Calvarial Bone Defects: I. Differences in the Cellular Response to Demineralized Bone Matrix Implanted in Calvarial Defects and in Subcutaneous Sites

1999 ◽  
Vol 65 (2) ◽  
pp. 156-165 ◽  
Author(s):  
J. Wang ◽  
M. J. Glimcher
Keyword(s):  
Cellular Response ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Defects ◽  
Calvarial Bone ◽  
Calvarial Defects ◽  
Demineralized Bone

Accelerated repair of cortical bone defects using a synthetic extracellular matrix to deliver human demineralized bone matrix

2006 ◽  
Vol 24 (7) ◽  
pp. 1454-1462 ◽  
Author(s):  
Yanchun Liu ◽  
Shama Ahmad ◽  
Xiao Zheng Shu ◽  
R. Kent Sanders ◽  
Sally Anne Kopesec ◽  
...  
Keyword(s):  
Extracellular Matrix ◽  
Cortical Bone ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Defects ◽  
Demineralized Bone

scholarly journals Formulation and Characterization of a New Injectable Bone Substitute Composed PVA/borax /CaCO3 and Demineralized Bone Matrix

2021 ◽  
Author(s):  
Daniela Medrano-David ◽  
Aura Maria Lopera ◽  
Martha Elena Londoño ◽  
Pedronel Araque-Marín
Keyword(s):  
Bone Substitute ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Particulate Material ◽  
Bone Tissue Regeneration ◽  
Bone Implant ◽  
Injectable Scaffold ◽  
The World ◽  
Demineralized Bone

The occurrence of bone-related disorders and diseases has increased dramatically in recent years around the world. Demineralized bone matrix (DBM) has been widely used as a bone implant due to its osteoinduction and bioactivity. However, the use of DBM is limited because it is a particulate material, which makes it difficult to manipulate and implant with precision, in addition, these particles are susceptible to migrate to other sites. To address this situation, DBM is commonly incorporated into a variety of carriers. An injectable scaffold has advantages over bone grafts or preformed scaffolds, such as the ability to flow and fill the bone defect. The aim of this research is to develop a DBM carrier with such viscoelastic properties to obtain an injectable bone substitute (IBS). The DBM carrier developed consisted of a PVA/glycerol network cross-linked with borax and reinforced with CaCO3 as a pH neutralizer, porosity generator, and source of Ca. The physicochemical properties were determined by the injectability test, FTIR, SEM, and TGA. Porosity, degradation, bioactivity, possible cytotoxic effect, and proliferation in osteoblasts were also determined. The results show that the developed material has great potential to be used in bone tissue regeneration

Characterization of Bone Defect Repair in Young and Aged Rat Femur Induced by Xenogenic Demineralized Bone Matrix

2002 ◽  
Vol 73 (9) ◽  
pp. 1003-1009 ◽  
Author(s):  
Paola Torricelli ◽  
Milena Fini ◽  
Gianluca Giavaresi ◽  
Lia Rimondini ◽  
Roberto Giardino
Keyword(s):  
Bone Defect ◽  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Rat Femur ◽  
Aged Rat ◽  
Bone Defect Repair ◽  
Defect Repair ◽  
Demineralized Bone

scholarly journals Temporal and spatial immunolocalization of osteopontin in the repair of orthopaedic bone defects treated with demineralized bone matrix

2019 ◽  
Vol 21 (1) ◽  
pp. 53-68
Author(s):  
S.A. Audisio ◽  
◽  
P.G. Vaquero ◽  
E.C. Verna ◽  
A.L. Cristofolini ◽  
...  
Keyword(s):  
Demineralized Bone Matrix ◽  
Bone Matrix ◽  
Bone Defects ◽  
Temporal And Spatial ◽  
Demineralized Bone
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