Power Spectral Analysis of Vertebral Trabecular Bone Structure from Radiographs: Orientation Dependence and Correlation with Bone Mineral Density and Mechanical Properties

1998 ◽  
Vol 63 (6) ◽  
pp. 482-489 ◽  
Author(s):  
J. Millard ◽  
P. Augat ◽  
T. M. Link ◽  
M. Kothari ◽  
D. C. Newitt ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Spectral Analysis ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Bone Structure ◽  
Power Spectral Analysis ◽  
Orientation Dependence ◽  
Mineral Density ◽  
Power Spectral

Changes in Bone Mineral Density and Mechanical Properties Due to Alcohol and Ovariectomy in Trabecular Bone of Female Rats

2002 ◽  
Author(s):  
Harry A. Hogan ◽  
H. Wayne Sampson
Keyword(s):  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Animal Model ◽  
Risk Factor ◽  
Alcohol Consumption ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Female Rats ◽  
Mineral Density ◽  
Rat Animal Model

Alcohol consumption is a known risk factor exacerbating postmenopausal osteoporosis [1,2]. The current study was undertaken to investigate these effects using the rat animal model. Recent studies with rats have shown deleterious effects due to alcohol [3,4], but no significant effects when combined estrogen deficiency induced by ovariectomy (OVX) [5]. This last study did not report mechanical properties, however. The objective of the current study was to investigate the effects of alcohol and OVX on trabecular bone mechanical properties and bone mineral density (BMD) in adult female rats. An important issue in evaluating osteoporosis and related bone maladies clinically is the relation between bone mineral density (BMD) and fracture risk or incidence. Thus, an additional goal of the current study was to examine the relationships (correlations) between trabecular bone BMD and mechanical properties.

VALIDATION OF THE USE OF FRACTIONAL QUANTITATIVE COMPUTED TOMOGRAPHY BASED ON THE MECHANICAL PROPERTIES OF TRABECULAR BONE

2010 ◽  
Vol 24 (15n16) ◽  
pp. 2670-2675
Author(s):  
JONG MIN LEE ◽  
YONG MIN CHANG ◽  
GUANG HU JIN ◽  
JONG HYOUNG KIM ◽  
CHANG MIN SUH
Keyword(s):  
Computed Tomography ◽  
Mechanical Properties ◽  
Bone Mineral Density ◽  
Compressive Strength ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Quantitative Computed Tomography ◽  
Mineral Density

The fractional quantitative computed tomography (fQCT) to determine both quantity and distribution of bone mineral was evaluated based on the mechanical properties of trabecular bone. Using quantitative computed tomography (QCT), bone mineral density was measured at 46 areas from 5 bovine tibias. Subsequently, fQCT was measured by the proportion of pixels showing a bone mineral density greater than 290 mg/ml. Based on the mechanical properties of the bone specimens, the QCT and the fQCT were compared. The fQCT showed a significant correlation with the compressive strength with superiority to the QCT.

scholarly journals rhIGF-1 Treatment Increases Bone Mineral Density and Trabecular Bone Structure in Children with PAPP-A2 Deficiency

2018 ◽  
Vol 89 (3) ◽  
pp. 200-204 ◽  
Author(s):  
Federico G. Hawkins-Carranza ◽  
María T. Muñoz-Calvo ◽  
Gabriel Á. Martos-Moreno ◽  
Gonzalo Allo-Miguel ◽  
Luis Del Río ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Body Composition ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Bone Structure ◽  
Stop Codon ◽  
Premature Stop Codon ◽  
Whole Body ◽  
Homozygous Mutation ◽  
Mineral Density

Aim: Our objective was to determine changes in bone mineral density (BMD), trabecular bone score (TBS), and body composition after 2 years of therapy with recombinant human insulin-like growth factor-1 (rhIGF-1) in 2 prepubertal children with a complete lack of circulating PAPP-A2 due to a homozygous mutation in PAPP-A2 (p.D643fs25*) resulting in a premature stop codon. Methods: Body composition, BMD, and bone structure were determined by dual-energy X-ray absorptiometry at baseline and after 1 and 2 years of rhIGF-1 treatment. Results: Height increased from 132 to 145.5 cm (patient 1) and from 111.5 to 124.5 cm (patient 2). Bone mineral content increased from 933.40 to 1,057.97 and 1,152.77 g in patient 1, and from 696.12 to 773.26 and 911.51 g in patient 2, after 1 and 2 years, respectively. Whole-body BMD also increased after 2 years of rhIGF-1 from baseline 0.788 to 0.869 g/cm2 in patient 1 and from 0.763 to 0.829 g/cm2 in patient 2. After 2 years of treatment, both children had an improvement in TBS. During therapy, a slight increase in body fat mass was seen, with a concomitant increase in lean mass. No adverse effects were reported. Conclusion: Two years of rhIGF-1 improved growth, with a tendency to improve bone mass and bone microstructure and to modulate body composition.

VALIDATION OF A BONE MINERAL DENSITY CALIBRATION PROTOCOL FOR MICRO-COMPUTED TOMOGRAPHY

2017 ◽  
Vol 17 (01) ◽  
pp. 1750015
Author(s):  
FABIO BARUFFALDI ◽  
ROSSELLA STOICO ◽  
SIMONE TASSANI ◽  
LAURA MECOZZI ◽  
STEFANO FALCIONI ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Bone Structure ◽  
Tissue Type ◽  
Micro Ct ◽  
Micro Computed Tomography ◽  
Mineral Density ◽  
Calibration Protocol

Micro-computed tomography (micro-CT) is widely used for in vitro studies to characterize bone structure at the resolution of 10–100 microns. However, a densitometric calibration protocol is necessary to convert the X-ray attenuation coefficient provided by micro-CT in bone mineral density (BMD). The lastest one has an important role to improve the accuracy of subject-specific finite element models. This work presents a simple calibration protocol based on the use of solid hydroxyapatite phantoms with the correction of the beam hardening effect. The method was validated in comparison to ashing measures of cortical and trabecular human bone. In addition, bone samples tissue mineral density (TMD) was calculated with two different methods. The correlation between ash density and BMD was linear both for cortical ([Formula: see text]) and trabecular bone ([Formula: see text]). The analysis stratified by tissue type versus the pooled analysis confirmed the validity of a common linear model for both types of tissue ([Formula: see text]). Despite its simplicity, the correlation obtained in this work does not depend on the acquisition settings of the micro-CT. TMD was shown to be dependent on the tissue investigated, with values in the range of 1.15–1.21[Formula: see text]mg/mm3 for trabecular bone, and 1.19–1.29[Formula: see text]mg/mm3 for cortical bone. Results are of some interest for generating micro finite elements models.

Abstract #225 Trabecular Bone Score is Lower in Patients on Permanent Hemodialysis Compared to Controls Matched for Bone Mineral Density

2019 ◽  
Vol 25 ◽  
pp. 77-78
Author(s):  
Roxana Dusceac ◽  
Dan Niculescu ◽  
Madalina Sorohan ◽  
Ramona Dobre ◽  
Catalina Poiana
Keyword(s):  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Trabecular Bone Score ◽  
Mineral Density

Inadequate vitamin D status adversely affects trabecular bone mineral density in 14-18 year old adolescents

2017 ◽  
Author(s):  
Taryn Smith ◽  
Laura Tripkovic ◽  
Camilla Damsgaard ◽  
Christian Molgaard ◽  
Aine Hennessy ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Vitamin D ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Vitamin D Status ◽  
Mineral Density ◽  
Trabecular Bone Mineral Density

A study of the homogeneity of the trabecular bone mineral density in the calcaneus

1987 ◽  
Vol 14 (4) ◽  
pp. 687-690 ◽  
Author(s):  
Shailendra S. Shukla ◽  
Min Y. Leu ◽  
Thomas Tighe ◽  
Bradford Krutoff ◽  
J. Duncan Craven ◽  
...  
Keyword(s):  
Bone Mineral Density ◽  
Trabecular Bone ◽  
Bone Mineral ◽  
Mineral Density ◽  
Trabecular Bone Mineral Density
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