Blockade of phencyclidine-induced hyperlocomotion by olanzapine, clozapine and serotonin receptor subtype selective antagonists in mice

1997 ◽  
Vol 129 (1) ◽  
pp. 79-84 ◽  
Author(s):  
S. D. Gleason ◽  
Harlan E. Shannon
Keyword(s):  
Serotonin Receptor ◽  
Receptor Subtype ◽  
Selective Antagonists ◽  
Subtype Selective

The design of novel methoctramine-related tetraamines as muscarinic receptor subtype selective antagonists

Life Sciences ◽  
1995 ◽  
Vol 56 (11-12) ◽  
pp. 837-844 ◽  
Author(s):  
Carlo Melchiorre ◽  
Anna Minarini ◽  
Roberta Budriesi ◽  
Alberto Chiarini ◽  
Santi Spampinato ◽  
...  
Keyword(s):  
Muscarinic Receptor ◽  
Receptor Subtype ◽  
Muscarinic Receptor Subtype ◽  
Selective Antagonists ◽  
Subtype Selective

Endothelin antagonists: The rational design of combined and ETB receptor subtype selective antagonists

Peptides ◽  
1994 ◽  
pp. 598-600 ◽  
Author(s):  
W. L. Cody ◽  
A. M. Doherty ◽  
J. X. He ◽  
P. L. DePue ◽  
L. A. Waite ◽  
...  
Keyword(s):  
Rational Design ◽  
Receptor Subtype ◽  
Selective Antagonists ◽  
Endothelin Antagonists ◽  
Etb Receptor ◽  
Subtype Selective

Adenosine receptor subtype-selective antagonists in inflammation and hyperalgesia

2008 ◽  
Vol 377 (1) ◽  
pp. 65-76 ◽  
Author(s):  
Andras Bilkei-Gorzo ◽  
Osama M. Abo-Salem ◽  
Alaa M. Hayallah ◽  
Kerstin Michel ◽  
Christa E. Müller ◽  
...  
Keyword(s):  
Adenosine Receptor ◽  
Receptor Subtype ◽  
Selective Antagonists ◽  
Subtype Selective

scholarly journals Comparison of human and porcine gastric clasp and sling fiber contraction by M2and M3muscarinic receptors

2010 ◽  
Vol 298 (4) ◽  
pp. G530-G534 ◽  
Author(s):  
Anil K. Vegesna ◽  
Alan S. Braverman ◽  
Larry S. Miller ◽  
Ronald J. Tallarida ◽  
Mansoor I. Tiwana ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Muscarinic Receptor ◽  
Muscarinic Receptors ◽  
Gastroesophageal Junction ◽  
Muscle Fibers ◽  
Receptor Subtype ◽  
Muscarinic Receptor Subtype ◽  
Selective Antagonists ◽  
Subtype Selective ◽  
Fiber Contraction

To compare the gastroesophageal junction of the human with the pig, M2and M3receptor densities and the potencies of M2and M3muscarinic receptor subtype selective antagonists were determined in gastric clasp and sling smooth muscle fibers. Total muscarinic and M2receptors are higher in pig than human clasp and sling fibers. M3receptors are higher in human compared with pig sling fibers but lower in human compared with pig clasp fibers. Clasp fibers have fewer M3receptors than sling fibers in both humans and pigs. Similar to human clasp fibers, pig clasp fibers contract significantly less than pig sling fibers. Analysis of the methoctramine Schild plot suggests that M2receptors are involved in mediating contraction in pig clasp and sling fibers. Darifenacin potency suggests that M3receptors mediate contraction in pig sling fibers and that M2and M3receptors mediate contraction in pig clasp fibers. Taken together, the data suggest that both M2and M3muscarinic receptors mediate the contraction in both pig clasp and sling fibers similar to human clasp and sling fibers.

Hydrazides of clozapine: A new class of D1 dopamine receptor subtype selective antagonists

2006 ◽  
Vol 16 (17) ◽  
pp. 4543-4547 ◽  
Author(s):  
T.K. Sasikumar ◽  
D.A. Burnett ◽  
H. Zhang ◽  
A. Smith-Torhan ◽  
A. Fawzi ◽  
...  
Keyword(s):  
Dopamine Receptor ◽  
Receptor Subtype ◽  
New Class ◽  
Selective Antagonists ◽  
D1 Dopamine Receptor ◽  
Subtype Selective

Assessment for the Role of Serotonin Receptor Subtype 3 for the Analgesic Action of Morphine at the Spinal Level

2005 ◽  
Vol 18 (2) ◽  
pp. 113
Author(s):  
Myung Ha Yoon ◽  
Hong Buem Bae ◽  
Jeong Il Choi ◽  
Seok Jae Kim ◽  
Chang Mo Kim ◽  
...  
Keyword(s):  
Serotonin Receptor ◽  
Receptor Subtype ◽  
Analgesic Action ◽  
Spinal Level ◽  
Subtype 3
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