Improved incidental memory with nicotine after semantic processing, but not after phonological processing

2001 ◽  
Vol 153 (2) ◽  
pp. 258-263 ◽  
Author(s):  
David M. Warburton ◽  
Abigail Skinner ◽  
Christopher D. Martin
Keyword(s):  
Phonological Processing ◽  
Semantic Processing ◽  
Incidental Memory

scholarly journals Early Phonological Neural Specialization Predicts Later Growth in Word Reading Skills

2019 ◽  
Author(s):  
Brianna L. Yamasaki ◽  
Karla Kay McGregor ◽  
James R. Booth
Keyword(s):  
Phonological Processing ◽  
Semantic Processing ◽  
Reading Skills ◽  
Word Reading ◽  
Superior Temporal Gyrus ◽  
Preliminary Evidence ◽  
Reading Growth ◽  
Best Fitting ◽  
And Performance ◽  
Performance Results

According to the Interactive Specialization Theory, cognitive skill development is facilitated by a process of neural specialization. In line with this theory, the current study investigated whether neural specialization for phonological and semantic processing at 5-to-6 years old was predictive of growth in word reading skills from 5-to-8 years old. Specifically, four regression models were estimated in which reading growth was predicted from: (1) an intercept-only model, (2) measures of semantic and phonological neural specialization, (3) performance on semantic and phonological behavioral tasks, or (4) a combination of neural specialization and behavioral performance. Results from the preregistered analyses revealed little evidence in favor of the hypothesis that early semantic and phonological skills predict growth in reading. However, results from the exploratory analyses, which included a larger sample, focused exclusively on the phonological predictors, and investigated relative growth in reading, demonstrated strong evidence that variability in phonological processing is predictive of growth in word reading skills. Specifically, the best fitting model included both measures of phonological neural specialization within the posterior superior temporal gyrus and performance on a phonological behavioral task. This work provides important preliminary evidence in favor of the Interactive Specialization Theory and, more specifically, for the role of phonological neural specialization in the development of early word reading skills.

Contemporary model of language organization: an overview for neurosurgeons

2015 ◽  
Vol 122 (2) ◽  
pp. 250-261 ◽  
Author(s):  
Edward F. Chang ◽  
Kunal P. Raygor ◽  
Mitchel S. Berger
Keyword(s):  
Speech Processing ◽  
Phonological Processing ◽  
Semantic Processing ◽  
Functional Organization ◽  
Inferior Frontal Gyrus ◽  
Superior Temporal Gyrus ◽  
Functional Neuroanatomy ◽  
Additional Information ◽  
Dorsal Pathway ◽  
Subcortical Mapping

Classic models of language organization posited that separate motor and sensory language foci existed in the inferior frontal gyrus (Broca's area) and superior temporal gyrus (Wernicke's area), respectively, and that connections between these sites (arcuate fasciculus) allowed for auditory-motor interaction. These theories have predominated for more than a century, but advances in neuroimaging and stimulation mapping have provided a more detailed description of the functional neuroanatomy of language. New insights have shaped modern network-based models of speech processing composed of parallel and interconnected streams involving both cortical and subcortical areas. Recent models emphasize processing in “dorsal” and “ventral” pathways, mediating phonological and semantic processing, respectively. Phonological processing occurs along a dorsal pathway, from the posterosuperior temporal to the inferior frontal cortices. On the other hand, semantic information is carried in a ventral pathway that runs from the temporal pole to the basal occipitotemporal cortex, with anterior connections. Functional MRI has poor positive predictive value in determining critical language sites and should only be used as an adjunct for preoperative planning. Cortical and subcortical mapping should be used to define functional resection boundaries in eloquent areas and remains the clinical gold standard. In tracing the historical advancements in our understanding of speech processing, the authors hope to not only provide practicing neurosurgeons with additional information that will aid in surgical planning and prevent postoperative morbidity, but also underscore the fact that neurosurgeons are in a unique position to further advance our understanding of the anatomy and functional organization of language.

Semantic and phonological processing in illiteracy

2004 ◽  
Vol 10 (6) ◽  
pp. 818-827 ◽  
Author(s):  
MARY H. KOSMIDIS ◽  
KYRANA TSAPKINI ◽  
VASILIKI FOLIA ◽  
CHRISTINA H. VLAHOU ◽  
GRIGORIS KIOSSEOGLOU
Keyword(s):  
Cognitive Processing ◽  
Language Processing ◽  
Phonological Processing ◽  
Oral Language ◽  
Semantic Processing ◽  
Formal Education ◽  
Functional Organization ◽  
Hemispheric Specialization ◽  
Cognitive Strategies ◽  
Phonological Information

Researchers of cognitive processing in illiteracy have proposed that the acquisition of literacy modifies the functional organization of the brain. They have suggested that, while illiterate individuals have access only to innate semantic processing skills, those who have learned the correspondence between graphemes and phonemes have several mechanisms available to them through which to process oral language. We conducted 2 experiments to verify that suggestion with respect to language processing, and to elucidate further the differences between literate and illiterate individuals in the cognitive strategies used to process oral language, as well as hemispheric specialization for these processes. Our findings suggest that semantic processing strategies are qualitatively the same in literates and illiterates, despite the fact that overall performance is augmented by increased education. In contrast, explicit processing of oral information based on phonological characteristics appears to be qualitatively different between literates and illiterates: effective strategies in the processing of phonological information depend upon having had a formal education, regardless of the level of education. We also confirmed the differential abilities needed for the processing of semantic and phonological information and related them to hemisphere-specific processing. (JINS, 2004,10, 818–827.)

scholarly journals Early Phonological Neural Specialization Predicts Later Growth in Word Reading Skills

2021 ◽  
Vol 15 ◽  
Author(s):  
Brianna L. Yamasaki ◽  
Karla K. McGregor ◽  
James R. Booth
Keyword(s):  
Phonological Processing ◽  
Semantic Processing ◽  
Reading Skills ◽  
Word Reading ◽  
Superior Temporal Gyrus ◽  
Behavioral Performance ◽  
Reading Growth ◽  
Best Fitting ◽  
Decisive Evidence ◽  
Performance Results

According to the Interactive Specialization Theory, cognitive skill development is facilitated by a process of neural specialization. In line with this theory, the current study investigated whether neural specialization for phonological and semantic processing at 5-to-6 years old was predictive of growth in word reading skills 2 years later. Specifically, four regression models were estimated in which reading growth was predicted from: (1) an intercept-only model; (2) measures of semantic and phonological neural specialization; (3) performance on semantic and phonological behavioral tasks; or (4) a combination of neural specialization and behavioral performance. Results from the preregistered analyses revealed little evidence in favor of the hypothesis that early semantic and phonological skills are predictive of growth in reading. However, results from the exploratory analyses, which included a larger sample, added age at Time 1 as a covariate, and investigated relative growth in reading, demonstrated decisive evidence that variability in phonological processing is predictive of reading growth. The best fitting model included both measures of specialization within the posterior superior temporal gyrus (pSTG) and behavioral performance. This work provides important evidence in favor of the Interactive Specialization Theory and, more specifically, for the role of phonological neural specialization in the development of early word reading skills.

Cognition, Metacognition, and Achievement of College Students with Learning Disabilities

2005 ◽  
Vol 28 (4) ◽  
pp. 261-272 ◽  
Author(s):  
Guy Trainin ◽  
H. Lee Swanson
Keyword(s):  
College Students ◽  
Learning Strategies ◽  
Phonological Processing ◽  
Help Seeking ◽  
Semantic Processing ◽  
Short Term Memory ◽  
Word Reading ◽  
Self Regulation ◽  
Students With Learning Disabilities ◽  
Students With Ld

This study examined the way successful college students with LD compensated for their deficits in phonological processing. Successful was defined as average or above-average grades in college coursework. The study compared the cognitive and metacognitive performance of students with and without LD (N=40). Although achievement levels for both groups were comparable, students with LD scored significantly lower than students without LD in word reading, processing speed, semantic processing, and short-term memory. Differences were also found between groups in self-regulation and number of hours of studying. Results showed that students with LD compensated for their processing deficits by relying on verbal abilities, learning strategies, and help seeking.

scholarly journals Triangulation of the neurocomputational architecture underpinning reading aloud

2015 ◽  
Vol 112 (28) ◽  
pp. E3719-E3728 ◽  
Author(s):  
Paul Hoffman ◽  
Matthew A. Lambon Ralph ◽  
Anna M. Woollams
Keyword(s):  
Individual Differences ◽  
Phonological Processing ◽  
Semantic Processing ◽  
Word Reading ◽  
Reading Aloud ◽  
Brain Regions ◽  
Semantic Knowledge ◽  
Cognitive Models ◽  
Causal Modeling ◽  
Neural Pathways

The goal of cognitive neuroscience is to integrate cognitive models with knowledge about underlying neural machinery. This significant challenge was explored in relation to word reading, where sophisticated computational-cognitive models exist but have made limited contact with neural data. Using distortion-corrected functional MRI and dynamic causal modeling, we investigated the interactions between brain regions dedicated to orthographic, semantic, and phonological processing while participants read words aloud. We found that the lateral anterior temporal lobe exhibited increased activation when participants read words with irregular spellings. This area is implicated in semantic processing but has not previously been considered part of the reading network. We also found meaningful individual differences in the activation of this region: Activity was predicted by an independent measure of the degree to which participants use semantic knowledge to read. These characteristics are predicted by the connectionist Triangle Model of reading and indicate a key role for semantic knowledge in reading aloud. Premotor regions associated with phonological processing displayed the reverse characteristics. Changes in the functional connectivity of the reading network during irregular word reading also were consistent with semantic recruitment. These data support the view that reading aloud is underpinned by the joint operation of two neural pathways. They reveal that (i) the ATL is an important element of the ventral semantic pathway and (ii) the division of labor between the two routes varies according to both the properties of the words being read and individual differences in the degree to which participants rely on each route.

scholarly journals Behavioral Effects of Chronic Gray and White Matter Stroke Lesions in a Functionally Defined Connectome for Naming

2018 ◽  
Vol 32 (6-7) ◽  
pp. 613-623 ◽  
Author(s):  
Shihui Xing ◽  
Ayan Mandal ◽  
Elizabeth H. Lacey ◽  
Laura M. Skipper-Kallal ◽  
Jinsheng Zeng ◽  
...  
Keyword(s):  
White Matter ◽  
Left Hemisphere ◽  
Phonological Processing ◽  
Semantic Processing ◽  
Structural Connectivity ◽  
Dorsal Stream ◽  
Naming Task ◽  
Brain Regions ◽  
Lesion Size ◽  
The Impact

Background. In functional magnetic resonance imaging studies, picture naming engages widely distributed brain regions in the parietal, frontal, and temporal cortices. However, it remains unknown whether those activated areas, along with white matter pathways between them, are actually crucial for naming. Objective. We aimed to identify nodes and pathways implicated in naming in healthy older adults and test the impact of lesions to the connectome on naming ability. Methods. We first identified 24 cortical nodes activated by a naming task and reconstructed anatomical connections between these nodes using probabilistic tractography in healthy adults. We then used structural scans and fractional anisotropy (FA) maps in 45 patients with left hemisphere stroke to assess the relationships of node and pathway integrity to naming, phonology, and nonverbal semantic ability. Results. We found that mean FA values in 13 left hemisphere white matter tracts within the dorsal and ventral streams and 1 interhemispheric tract significantly related to naming scores after controlling for lesion size and demographic factors. In contrast, lesion loads in the cortical nodes were not related to naming performance after controlling for the same variables. Among the identified tracts, the integrity of 4 left hemisphere ventral stream tracts related to nonverbal semantic processing and 1 left hemisphere dorsal stream tract related to phonological processing. Conclusions. Our findings reveal white matter structures vital for naming and its subprocesses. These findings demonstrate the value of multimodal methods that integrate functional imaging, structural connectivity, and lesion data to understand relationships between brain networks and behavior.

scholarly journals The Left Posterior Superior Temporal Gyrus Participates Specifically in Accessing Lexical Phonology

2008 ◽  
Vol 20 (9) ◽  
pp. 1698-1710 ◽  
Author(s):  
William W. Graves ◽  
Thomas J. Grabowski ◽  
Sonya Mehta ◽  
Prahlad Gupta
Keyword(s):  
Phonological Processing ◽  
Repetition Priming ◽  
Semantic Processing ◽  
Superior Temporal Gyrus ◽  
Repetition Suppression ◽  
Left Posterior ◽  
Whole Word ◽  
Conjunction Analysis ◽  
Lexical Phonology ◽  
Phonological Access

Impairments in phonological processing have been associated with damage to the region of the left posterior superior temporal gyrus (pSTG), but the extent to which this area supports phonological processing, independent of semantic processing, is less clear. We used repetition priming and neural repetition suppression during functional magnetic resonance imaging (fMRI) in an auditory pseudoword repetition task as a semantics-free model of lexical (whole-word) phonological access. Across six repetitions, we observed repetition priming in terms of decreased reaction time and repetition suppression in terms of reduced neural activity. An additional analysis aimed at sublexical phonology did not show significant effects in the areas where repetition suppression was observed. To test if these areas were relevant to real word production, we performed a conjunction analysis with data from a separate fMRI experiment which manipulated word frequency (a putative index of lexical phonological access) in picture naming. The left pSTG demonstrated significant effects independently in both experiments, suggesting that this area participates specifically in accessing lexical phonology.

Semantic Processing in the Left Inferior Prefrontal Cortex: A Combined Functional Magnetic Resonance Imaging and Transcranial Magnetic Stimulation Study

2003 ◽  
Vol 15 (1) ◽  
pp. 71-84 ◽  
Author(s):  
Joseph T. Devlin ◽  
Paul M. Matthews ◽  
Matthew F. S. Rushworth
Keyword(s):  
Magnetic Resonance Imaging ◽  
Prefrontal Cortex ◽  
Transcranial Magnetic Stimulation ◽  
Magnetic Resonance ◽  
Functional Magnetic Resonance Imaging ◽  
Phonological Processing ◽  
Magnetic Stimulation ◽  
Semantic Processing ◽  
Functional Magnetic Resonance ◽  
Resonance Imaging

The involvement of the left inferior prefrontal cortex (LIPC) in phonological processing is well established from both lesion-deficit studies with neurological patients and functional neuroimaging studies of normals. Its involvement in semantic processing, on the other hand, is less clear. Although many imaging studies have demonstrated LIPC activation during semantic tasks, this may be due to implicit phonological processing. This article presents two experiments investigating semantic functions in the LIPC. Results from a functional magnetic resonance imaging experiment demonstrated that both semantic and phonological processing activated a common set of areas within this region. In addition, there was a reliable increase in activation for semantic relative to phonological decisions in the anterior LIPC while the opposite comparison (phonological vs. semantic decisions) revealed an area of enhanced activation within the posterior LIPC. A second experiment used transcranial magnetic stimulation (TMS) to temporarily interfere with neural information processing in the anterior portion of the LIPC to determine whether this region was essential for normal semantic performance. Both repetitive and single pulse TMS significantly slowed subjects' reactions for the semantic but not for the perceptual control task. Our results clarify the functional anatomy of the LIPC by demonstrating that anterior and posterior regions contribute to both semantic and phonological processing, albeit to different extents. In addition, the findings go beyond simply establishing a correlation between semantic processing and activation in the LIPC and demonstrate that a transient disruption of processing selectively interfered with semantic processing.

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