scholarly journals Correction to: Metabotropic group II glutamate receptors in the basolateral amygdala mediate cue‑triggered increases in incentive motivation

2021 ◽  
Vol 238 (10) ◽  
pp. 2919-2922
Author(s):  
Caroline Garceau ◽  
Anne‑Noël Samaha ◽  
Thomas Cordahi ◽  
Alice Servonnet ◽  
Shaun Yon‑Seng Khoo
Keyword(s):  
Glutamate Receptors ◽  
Basolateral Amygdala ◽  
Incentive Motivation ◽  
Group Ii

scholarly journals Metabotropic group II glutamate receptors in the basolateral amygdala mediate cue-triggered increases in incentive motivation

2021 ◽  
Author(s):  
Caroline Garceau ◽  
Anne-Noël Samaha ◽  
Thomas Cordahi ◽  
Alice Servonnet ◽  
Shaun Yon-Seng Khoo
Keyword(s):  
Glutamate Receptors ◽  
Basolateral Amygdala ◽  
Incentive Motivation ◽  
Group Ii

scholarly journals Metabotropic group II glutamate receptors in the basolateral amygdala mediate cue-triggered increases in incentive motivation

2021 ◽  
Author(s):  
Caroline Garceau ◽  
Anne-Noël Samaha ◽  
Thomas Cordahi ◽  
Alice Servonnet ◽  
Shaun Yon-Seng Khoo
Keyword(s):  
Basolateral Amygdala ◽  
Free Water ◽  
Incentive Motivation ◽  
Sprague Dawley ◽  
Glutamate Signaling ◽  
Reward Seeking ◽  
Sprague Dawley Rats ◽  
Conditioned Approach ◽  
Group Ii ◽  
Motor Effects

Rationale: Reward-associated cues can trigger incentive motivation for reward and invigorate reward-seeking behaviour via Pavlovian-to-instrumental transfer (PIT). Glutamate signaling within the basolateral amygdala (BLA) modulates cue-triggered increases in incentive motivation. However, the role of BLA metabotropic group II glutamate (mGlu2/3) receptors is largely unknown. Objectives: In Experiment 1, we characterized cue-triggered increases in incentive motivation for water reward using the PIT paradigm. In Experiment 2, we assessed the influence of intra-BLA microinjections of the mGlu2/3 receptor agonist LY379268 on this effect. Methods: Water-restricted male Sprague-Dawley rats learned to press a lever for water. Separately, they learned to associate one of two auditory cues with free water. On test days, rats could lever press under extinction conditions (no water), with intermittent, non-contingent CS+ and CS- presentations. In Experiment 1, rats were tested under baseline conditions. In Experiment 2, rats received intra-BLA microinjections of LY379268 (0, 3 and 6 μg/hemisphere) before testing. Results: Across experiments, CS+, but not CS- presentations increased water-associated lever pressing during testing, even though responding was reinforced neither by water nor the CS+. Intra-BLA LY379268 abolished both CS+ potentiated pressing on the water-associated lever and CS+ evoked conditioned approach to the site of water delivery. LY379268 did not influence locomotion or instrumental and Pavlovian response rates during intervals between CS presentations or during the CS-, indicating no motor effects. Conclusions: mGlu2/3 receptor activity in the BLA mediates CS-triggered potentiation of incentive motivation for reward, suppressing both CS-induced increases in instrumental pursuit of the reward and anticipatory approach behaviour.

scholarly journals HDAC and HAT Inhibitors Differently Affect Analgesia Mediated by Group II Metabotropic Glutamate Receptors

2014 ◽  
Vol 10 ◽  
pp. 1744-8069-10-68 ◽  
Author(s):  
Magda Zammataro ◽  
Maria Angela Sortino ◽  
Carmela Parenti ◽  
Robert W Gereau ◽  
Santina Chiechio
Keyword(s):  
Glutamate Receptors ◽  
Metabotropic Glutamate Receptors ◽  
Metabotropic Glutamate ◽  
Group Ii

Role of glutamate receptors of central and basolateral amygdala nuclei on retrieval and reconsolidation of taste aversive memory

2014 ◽  
Vol 111 ◽  
pp. 35-40 ◽  
Author(s):  
Paola Garcia-delaTorre ◽  
Consuelo Pérez-Sánchez ◽  
Kioko Guzmán-Ramos ◽  
Federico Bermúdez-Rattoni
Keyword(s):  
Glutamate Receptors ◽  
Basolateral Amygdala
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