Unbalanced Diet to Lower Serum Cholesterol Level is a Risk Factor for Postmenopausal Osteoporosis and Distal Forearm Fracture

2001 ◽  
Vol 12 (4) ◽  
pp. 296-301 ◽  
Author(s):  
M. Varenna ◽  
L. Binelli ◽  
F. Zucchi ◽  
D. Ghiringhelli ◽  
L. Sinigaglia
Keyword(s):  
Risk Factor ◽  
Postmenopausal Osteoporosis ◽  
Serum Cholesterol Level ◽  
Forearm Fracture ◽  
Distal Forearm ◽  
Distal Forearm Fracture ◽  
Lower Serum ◽  
Lower Serum Cholesterol ◽  
Lower Serum Cholesterol Level ◽  
Unbalanced Diet

scholarly journals Effect of simvastatin on thrombopoiesis in porcine bone marrow

2019 ◽  
Vol 63 (1) ◽  
pp. 117-121 ◽  
Author(s):  
Anna Snarska ◽  
Dominika Wysocka ◽  
Liliana Rytel
Keyword(s):  
Bone Marrow ◽  
Serum Cholesterol Level ◽  
Porcine Model ◽  
Dependent Manner ◽  
Platelet Volume ◽  
Lower Serum ◽  
Pharmacological Agents ◽  
Lower Serum Cholesterol ◽  
Cytological Evaluation ◽  
Lower Serum Cholesterol Level

Abstract Introduction: Statins are pharmacological agents commonly used to lower serum cholesterol level. The aim of the experiment was to investigate the effect of the statin simvastatin on thrombopoiesis in the porcine model because it is the closest to the human one regarding physiological and genetic similarities. Material and Methods: The study was conducted on a group of 32 pigs randomly divided into two equal groups: control and experimental. The pigs were treated for 28 and 56 days with simvastatin in a dose of 40 mg per day per animal. Cytological evaluation of bone marrow smears was performed to assess the average number of all types of cells during thrombopoiesis as was analysis of haematological parameters to assess PLT and MPV. Results: During the course of the experiment statistically significant changes in the number of promegakaryocytes were observed. Other parameters also showed some fluctuations during the study. However, these changes were not statistically significant. Conclusion: The obtained results clearly indicate a toxic influence of simvastatin on the process of thrombopoiesis and prove that statins reduce mean platelet volume, thus affecting the process of clot formation through the period of administration in a duration-dependent manner.

scholarly journals Distal forearm fracture as risk factor for vertebral osteoporosis

BMJ ◽  
1994 ◽  
Vol 308 (6943) ◽  
pp. 1543-1544 ◽  
Author(s):  
N F A Peel ◽  
N A Barrington ◽  
T W D Smith ◽  
R Eastell
Keyword(s):  
Risk Factor ◽  
Forearm Fracture ◽  
Distal Forearm ◽  
Distal Forearm Fracture ◽  
Vertebral Osteoporosis

X-ray Follow-up after Open Reduction Internal Fixation of Distal Forearm Fracture

2020 ◽  
Author(s):  
Henrik Johan Sjølander ◽  
Sune Jauffred ◽  
Michael Brix ◽  
Per H. Gundtoft
Keyword(s):  
Diagnostic Imaging ◽  
Forearm Fracture ◽  
Minimal Risk ◽  
Distal Forearm ◽  
Forearm Fractures ◽  
Distal Forearm Fracture ◽  
Standard Regimen ◽  
Prolonged Immobilization ◽  
Distal Forearm Fractures

Abstract Background Following surgery, the standard regimen for fractures of the distal forearm includes radiographs taken 2-weeks postoperatively. However, it is unclear whether these radiographs have any therapeutic risks or benefits for patients. Objective The purpose of this study is to determine the importance of radiographs taken 2-weeks after surgery on distal forearm fractures, especially if it leads to further operations, and to establish whether this practice should be continued. Materials and Methods This is a retrospective cohort study of patients with a distal forearm fracture treated surgically with a volar locking plate at two university hospitals in Denmark. Standard aftercare at both departments is 2 weeks in a cast. Patients attend a 2-week follow-up, at which the cast is replaced with a removable orthosis and radiographs are taken. It was recorded whether these radiographs had resulted in any change of treatment in terms of further operations, prolonged immobilization, additional clinical follow-up, or additional diagnostic imaging. Results A total of 613 patients were included in the study. The radiographs led to a change of standard treatment for 3.1% of the patients. A second operation was required by 1.0%; 0.5% were treated with prolonged immobilization, and 1.6% had additional outpatient follow-up due to the findings on the radiographs. Additional diagnostic imaging was performed on 1.9% of the patients. Conclusion The radiographs taken at the 2-weeks follow-up resulted in a change of treatment in 3.1% of the cases. Given the low cost and minimal risk of radiographs of an extremity, we concluded that the benefits outweigh the costs of routine radiographs taken 2 weeks after surgical treatment of distal forearm fractures.

Perimenopausal risk of falling and incidence of distal forearm fracture

Maturitas ◽  
1989 ◽  
Vol 11 (4) ◽  
pp. 342
Author(s):  
S.J. Winner ◽  
C.A. Morgan ◽  
J Grimley Evans
Keyword(s):  
Forearm Fracture ◽  
Distal Forearm ◽  
Distal Forearm Fracture ◽  
Risk Of Falling

scholarly journals Patients with femoral or distal forearm fracture in Germany: a prospective observational study on health care situation and outcome

2006 ◽  
Vol 6 (1) ◽  
Author(s):  
Heinz G Endres ◽  
Burkhard Dasch ◽  
Margitta Lungenhausen ◽  
Christoph Maier ◽  
Rüdiger Smektala ◽  
...  
Keyword(s):  
Health Care ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Forearm Fracture ◽  
Distal Forearm ◽  
Distal Forearm Fracture ◽  
Care Situation
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