Determinants of Bone Loss in Elderly Men and Women: A Prospective Population-Based Study

1999 ◽  
Vol 10 (5) ◽  
pp. 384-391 ◽  
Author(s):  
E. Dennison ◽  
R. Eastell ◽  
C. H. D. Fall ◽  
S. Kellingray ◽  
P. J. Wood ◽  
...  
2005 ◽  
Vol 77 (3) ◽  
pp. 134-138 ◽  
Author(s):  
R. M. Reynolds ◽  
E. M. Dennison ◽  
B. R. Walker ◽  
H. E. Syddall ◽  
P. J. Wood ◽  
...  

PLoS ONE ◽  
2013 ◽  
Vol 8 (7) ◽  
pp. e69627 ◽  
Author(s):  
Philipp Mahlknecht ◽  
Stefan Kiechl ◽  
Bastiaan R. Bloem ◽  
Johann Willeit ◽  
Christoph Scherfler ◽  
...  

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Yoosun Cho ◽  
Seulggie Choi ◽  
Young Ho Yun ◽  
Belong Cho ◽  
Ji-Yeob Choi ◽  
...  

2015 ◽  
Vol 182 ◽  
pp. 126-131 ◽  
Author(s):  
Jennifer Glaus ◽  
Caroline L. Vandeleur ◽  
Aurélie M. Lasserre ◽  
Marie-Pierre F. Strippoli ◽  
Enrique Castelao ◽  
...  

2009 ◽  
Vol 32 (9) ◽  
pp. 780-785 ◽  
Author(s):  
Axel C Carlsson ◽  
Per E Wändell ◽  
Gunilla Journath ◽  
Ulf de Faire ◽  
Mai-Lis Hellénius

2016 ◽  
Vol 59 ◽  
pp. 18-23 ◽  
Author(s):  
Anna-Karin Danielsson ◽  
Andreas Lundin ◽  
Peter Allebeck ◽  
Emile Agardh

2001 ◽  
Vol 153 (5) ◽  
pp. 465-473 ◽  
Author(s):  
Gro K. Rosvold Berntsen ◽  
Vinjar Fønnebø ◽  
Anne Tollan ◽  
Anne Johanne Søgaard ◽  
Jeanette H. Magnus

2012 ◽  
Vol 16 (8) ◽  
pp. 1454-1462 ◽  
Author(s):  
Angela A Mulligan ◽  
Gunter GC Kuhnle ◽  
Marleen AH Lentjes ◽  
Veronica van Scheltinga ◽  
Natasha A Powell ◽  
...  

AbstractObjectiveA diet rich in phyto-oestrogens has been suggested to protect against a variety of common diseases but UK intake data on phyto-oestrogens or their food sources are sparse. The present study estimates the average intakes of isoflavones, lignans, enterolignans and coumestrol from 7 d food diaries and provides data on total isoflavone, lignan and phyto-oestrogen consumption by food group.DesignDevelopment of a food composition database for twelve phyto-oestrogens and analysis of soya food and phyto-oestrogen consumption in a population-based study.SettingMen and women, aged 40–79 years, from the general population participating in the Norfolk arm of the European Prospective Investigation into Cancer and Nutrition (EPIC-Norfolk) between 1993 and 1997, with nutrient and food data from 7 d food diaries.SubjectsA subset of 20 437 participants.ResultsThe median daily phyto-oestrogen intake for all men was 1199 μg (interquartile range 934–1537 μg; mean 1504 μg,sd1502 μg) and 888 μg for all women (interquartile range 710–1135 μg; mean 1205 μg,sd1701 μg). In soya consumers, median daily intakes were higher: 2861 μg in men (interquartile range 1304–7269 μg; mean 5051 μg,sd5031 μg) and 3142 μg in women (interquartile range 1089–7327 μg; mean 5396 μg,sd6092 μg). In both men and women, bread made the greatest contribution to phyto-oestrogen intake – 40·8 % and 35·6 %, respectively. In soya consumers, vegetable dishes and soya/goat's/sheep's milks were the main contributors – 45·7 % and 21·3 % in men and 38·4 % and 33·7 % in women, respectively.ConclusionsThe ability to estimate phyto-oestrogen intake in Western populations more accurately will aid investigations into their suggested effects on health.


Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Charlotte A Larsson ◽  
Bledar Daka ◽  
Margareta I Hellgren ◽  
Maria C Eriksson ◽  
Lennart Råstam ◽  
...  

Introduction: Clusters of metabolic variables and their effects on incidence of type 2 diabetes have been studied previously; however, little is known about the effects on diabetes from risk factor clusters including lifestyle and self-rated health. Hypothesis: We assessed the hypothesis that clusters of common cardiovascular risk factors, including lifestyle and self-rated health, can predict development of type 2 diabetes in men and women, respectively. Methods: In 2002-2005, 2816 men and women, 30-74 years, were randomly selected from two municipalities in southwestern Sweden and assessed with regard to cardiovascular/metabolic risk factors within the Skaraborg Project (76% participation). Participants performed an OGTT, had blood samples drawn, had anthropometric measurements and blood pressure taken, and answered validated questionnaires about e.g. leisure-time physical activity (with four answer alternatives from intensive to sedentary) and self-rated health (with five alternatives from excellent to very poor). Using the same protocol, 1332 participants from the baseline survey where re-examined in 2011-2014. After excluding those with diabetes at baseline, 1268 participants were included in this prospective population-based study. Results: Factor analysis (using varimax rotation) identified significant loadings (≥0.40) on the following three identical factors in men and women: the metabolic factor , comprising HOMA-ir, WHR, systolic blood pressure, and apolipoprotein B-to-A1 ratio; the vitality factor , comprising physical activity and self-rated health; and the addiction factor , comprising smoking and alcohol consumption. After a mean follow-up of 9.7±1.4 years, 76 cases of diabetes were identified; 46 in men and 30 in women. In a logistic regression analysis adjusted for all principal components, age, and educational level, the metabolic factor significantly predicted type 2 diabetes in both men (OR: 3.3, CI: 2.3-5.0) and women (OR: 3.5, CI: 2.2-5.6). Furthermore, a predictive effect of the vitality factor was also seen in women (OR: 1.8, CI: 1.2-2.9), but not in men (OR: 1.1, CI: 0.8-1.6), whereas the addiction factor had no effect in either men or women. Conclusions: This is to our knowledge the first time principle components of cardiovascular risk factors, including both metabolic and lifestyle variables, have been used to predict incidence of type 2 diabetes. The gender difference observed with regard to the combined impact of self-rated health and physical activity are novel and indicates a mechanism beside the metabolic syndrome that warrants further gender-specific exploration in future studies.


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