Spinal cord injury without radiographic abnormalities in children and adolescents: case report of a severe cervical spine lesion and review of literature

2000 ◽  
Vol 8 (3) ◽  
pp. 186-189 ◽  
Author(s):  
A. Beck ◽  
F. Gebhard ◽  
L. Kinzl ◽  
A. Rüter ◽  
E. Hartwig
2014 ◽  
Vol 11 (2) ◽  
pp. 150-153
Author(s):  
Pradipta Tripathy ◽  
Chidananda Dash ◽  
Aurobind Rath ◽  
S. Chakraborty ◽  
Jagannath Sahoo ◽  
...  

2020 ◽  
pp. 1-5
Author(s):  
Theresa L. Williamson ◽  
Andrew Cutler ◽  
Mary I. Cobb ◽  
Shervin Rahimpour ◽  
Eric R. Butler ◽  
...  

This study describes a patient with an autograft-derived spinal cord mass following transplantation of olfactory mucosa for treatment of cervical spine injury. The authors report the case of a 35-year-old man who suffered a complete spinal cord injury (SCI) at C5–6 in 2001. The patient underwent an olfactory mucosal cell implantation at the location of injury 4 years following initial trauma. Twelve years later, the patient presented with rapidly progressive decline in upper-extremity function as well as neuropathic pain. Imaging revealed a heterogeneously enhancing intramedullary mass from C3 to C7. At surgery, the patient was found to have a posttransplant mucinous mass. Each mucinous cyst was drained and a portion of the cyst wall was removed. Histological examination demonstrated ciliated epithelium-lined fibrous tissue, submucosal glands, and mucoid material, consistent with a transplant-derived tumor. This case report both documents a rare long-term complication of olfactory mucosal cell transplantation and serves as a cautionary tale encouraging prudent use of novel treatments in a vulnerable population of patients with severe SCI.


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