Does long-term continuous administration of pentoxifylline affect platelet function in the critically ill patient?

1996 ◽  
Vol 22 (7) ◽  
pp. 644-650 ◽  
Author(s):  
J. Boldt ◽  
M. M�ller ◽  
M. Heesen ◽  
S. Heyn ◽  
G. Hempelmann
Keyword(s):  
Critically Ill ◽  
Platelet Function ◽  
Critically Ill Patient ◽  
Continuous Administration

Does long-term continous administration of pentoxifylline affect platelet function in the critically ill patient?

1996 ◽  
Vol 22 (7) ◽  
pp. 644-650 ◽  
Author(s):  
J. Boldt ◽  
M. Müller ◽  
M. Heesen ◽  
S. Heyn ◽  
G. Hempelmann
Keyword(s):  
Critically Ill ◽  
Platelet Function ◽  
Critically Ill Patient

scholarly journals ACUTE KIDNEY INJURY DURING CRITICAL ILLNESS – A GLOBAL CHALLENGE

2019 ◽  
Vol 16 (2) ◽  
pp. 83-95
Author(s):  
M. Ostermann
Keyword(s):  
Acute Kidney Injury ◽  
Drug Therapy ◽  
Critically Ill ◽  
Kidney Injury ◽  
Critically Ill Patient ◽  
Infusion Therapy ◽  
Global Challenge ◽  
Nephrotoxic Drugs ◽  
Definition Of

The report is devoted to the problem of acute kidney injury (AKI) in critically ill patients. Currently, the clinical definition of AKI is based on the assessment of increasing serum creatinine, but this method has a number of significant drawbacks. Perhaps the use of biomarkers for early detection of renal injury will improve diagnostic results. Up to date, no specific drug therapy for AKI has no available. The therapeutic tactics are based on the assessment of the risk of development AKI in critically ill patient, hemodynamic optimization, revision of drug therapy to exclude nephrotoxic drugs and the use of renal replacement therapy (RRT). Despite the numerous studies and the presence of multiple researches of AKI, there are many unclear issues related, for example, how to choose tactics of infusion therapy, the use of vasopressor support in patients with AKI, the time of the beginning and the choice of the mode of RRT, the feasibility of combining several technologies of extracorporeal hemocorrection. It is important to define how to improve the short-term prognosis and the long-term consequences of renal dysfunction.

scholarly journals Saccharomyces cerevisiae fungemia in a critically ill patient with acute cholangitis and long term probiotic use

2019 ◽  
Vol 23 ◽  
pp. 23-25 ◽  
Author(s):  
Mustafa Fadhel ◽  
Swapnil Patel ◽  
Edward Liu ◽  
Michael Levitt ◽  
Arif Asif
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Critically Ill ◽  
Acute Cholangitis ◽  
Critically Ill Patient

scholarly journals Long-Term Sequelae of Severe Acute Kidney Injury in the Critically Ill Patient without Comorbidity: A Retrospective Cohort Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (3) ◽  
pp. e0121482 ◽  
Author(s):  
Gijs Fortrie ◽  
Susanne Stads ◽  
Albert-Jan H. Aarnoudse ◽  
Robert Zietse ◽  
Michiel G. Betjes
Keyword(s):  
Acute Kidney Injury ◽  
Cohort Study ◽  
Critically Ill ◽  
Retrospective Cohort Study ◽  
Retrospective Cohort ◽  
Kidney Injury ◽  
Critically Ill Patient

Levodopa Withdrawal Presenting as Fever in a Critically Ill Patient Receiving Concomitant Enteral Nutrition

2016 ◽  
Vol 29 (6) ◽  
pp. 574-578 ◽  
Author(s):  
Craig B. Whitman ◽  
Enyo Ablordeppey ◽  
Beth Taylor
Keyword(s):  
Enteral Nutrition ◽  
Critically Ill ◽  
Long Term Care ◽  
Care Facility ◽  
Critically Ill Patient ◽  
Shortness Of Breath ◽  
Term Care ◽  
Long Term Care Facility ◽  
Levodopa Withdrawal

Nutritional protein may decrease levodopa absorption and has resulted in withdrawal and neuroleptic malignant-like syndromes in critically ill patients. A 72-year-old male was admitted with shortness of breath. His medical history included Parkinson’s disease for over 30 years for which he took carbidopa/levodopa 5 times daily. The patient’s home medications were continued. On day 2, he was intubated and transferred to the intensive care unit (ICU). He was extubated the next day and reintubated on day 4. Enteral nutrition was initiated at 85 mL/h overnight. The patient’s carbidopa/levodopa was administered to limit coadministration with nutrition. Throughout his ICU stay, the patient did not demonstrate changes in mental status. Despite resolution of his pneumonia, he developed fever after administration of one dose overlapping with nutrition, with defervescence throughout the rest of the day. On hospital day 10, that dose was empirically increased. After this dosing change, the patient failed to develop fever during the rest of his hospital stay. On day 16, the patient was discharged to a long-term care facility without any other complications. Our case highlights the interaction between levodopa and enteral nutrition and the potential of fever as the sole sign of withdrawal.

scholarly journals Risk Factors for Acute Delirium in Critically Ill Adult Patients: A Systematic Review

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Ihsan Mattar ◽  
Moon Fai Chan ◽  
Charmaine Childs
Keyword(s):  
Risk Factors ◽  
Critically Ill ◽  
Functional Decline ◽  
Older Age ◽  
Adult Patients ◽  
Critically Ill Patient ◽  
Surgical Intensive Care ◽  
Mini Mental Status Examination ◽  
Reversible Condition

Background. Delirium is characterized by disturbances of consciousness, attention, cognition, and perception. Delirium is a serious but reversible condition associated with poor clinical outcomes. This has implications for the critically ill patient; the effects of delirium cause long term sequelae, principally cognitive deficits, and functional decline. Objectives. The objective of the paper was to describe risk factors associated with delirium in critically ill adult patients. Methods. Published and unpublished literature from 1990 to 2012, limited to English, was searched using ten databases. Results. Twenty-two studies were included in this paper. A large number of risk factors were presented in the literature; some of these were common across all settings whilst others were exclusive to the type of setting. Benzodiazepines and opioids were shown to be risk factors for delirium independent of setting. Conclusion. With regard to patients admitted to medical and surgical intensive care units, risk factors of older age and comorbidity were common. In the cardiac ICU, older age and lower Mini-Mental Status Examination scores were cited most often as risk factors for delirium, but other risk factors exclusive to the setting were also significant. Benzodiazepines were identified as the most significant pharmacological risk factor for delirium.

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