Malignant transformation of a giant-cell tumor in the distal radius. The prognostic value of the DNA-cytophotometry

2000 ◽  
Vol 29 (7) ◽  
pp. 0677-0683 ◽  
Author(s):  
I. Antal ◽  
Z. Sápi ◽  
M. Szendrôi
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Transformation ◽  
Distal Radius ◽  
Prognostic Value ◽  
Cell Tumor ◽  
Dna Cytophotometry

scholarly journals A Systematic Review and Meta-Analysis of En-Bloc vs Intralesional Resection for Giant Cell Tumor of Bone of the Distal Radius

2013 ◽  
Vol 7 (1) ◽  
pp. 103-108 ◽  
Author(s):  
Theresa J.C Pazionis ◽  
Hussain Alradwan ◽  
Benjamin M Deheshi ◽  
Robert Turcotte ◽  
Forough Farrokhyar ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Distal Radius ◽  
Wrist Joint ◽  
Meta Analysis ◽  
En Bloc Resection ◽  
Cell Tumor ◽  
En Bloc ◽  
Intralesional Curettage ◽  
Functional Benefit

Introduction: Surgical management of Giant Cell Tumor of Bone of the distal radius (GCTDR) remains controversial due to risk of local recurrence (LR) offset by functional limitations which result from en-bloc resection. This study aims to determine the oncologic and functional outcomes of wide excision (WE) vs intralesional curettage (IC) of GCTDR. Methods: A complete search of the applicable literature was done. Included studies reported on patients from the same cohort who were surgically treated for GCTDR with WE or IC. Two reviewers independently assessed all papers. The primary outcome measure was LR. Results: One-hundred-forty-one patients from six studies were included: 60 treated with WE, and 81 with IC. Five WE patients (8%) suffered LR whereas 25 IC patients (31%) did. The odds of LR were three times less in the WE group vs the IC group. MSTS1993 scores, where available, were on average 'good' with WE and 'excellent' with IC. Conclusions: Within statistical limitations the data support an attempt, where feasible, at wrist joint preservation and superior function with IC. Intralesional curettage is reasonable when the functional benefit outweighs the risk of recurrence as is the case in many cases of GCT of the distal radius.

Malignant Transformation of Giant Cell Tumor Affecting the Lower Lip

2015 ◽  
Vol 120 (2) ◽  
pp. e68
Author(s):  
JORGE ESQUICHE LEÓN ◽  
LUCIANA YAMAMOTO DE ALMEIDA ◽  
MARISOL MARTÍNEZ MARTÍNEZ ◽  
FERNANDA DOS SANTOS MOREIRA ◽  
ALÍCIA RUMAYOR PIÑA ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Transformation ◽  
Cell Tumor ◽  
Lower Lip

Primary malignant transformation of giant cell tumor of bone

2007 ◽  
Vol 62 (3) ◽  
pp. 89-93 ◽  
Author(s):  
Eric J. Heffernan ◽  
Paul J. O'Sullivan ◽  
Manoochehr Adibeig ◽  
Luck J. Louis ◽  
Anthony G. Ryan ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Transformation ◽  
Cell Tumor

scholarly journals Clinical and Radiographic Results of Reconstruction with Fibular Autograft for Distal Radius Giant Cell Tumor

2016 ◽  
Vol 8 (2) ◽  
pp. 196-204 ◽  
Author(s):  
Dian-wen Qi ◽  
Peng Wang ◽  
Zhao-ming Ye ◽  
Xiu-chun Yu ◽  
Yong-cheng Hu ◽  
...  
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Distal Radius ◽  
Cell Tumor ◽  
Fibular Autograft

scholarly journals Radius' Giant Cell Tumor: Allograft with Conservation of Distal Radioulnar Joint

2019 ◽  
Vol 08 (03) ◽  
pp. 215-220 ◽  
Author(s):  
S. Ruatti ◽  
M. Boudissa ◽  
P. Grobost ◽  
G. Kerschbaumer ◽  
J. Tonetti
Keyword(s):  
Range Of Motion ◽  
Giant Cell Tumor ◽  
Giant Cell ◽  
Distal Radius ◽  
Functional Results ◽  
Distal Radioulnar Joint ◽  
Cell Tumor ◽  
The Other ◽  
Radioulnar Joint

Purpose Giant cell tumor of the distal radius are frequent lesions, and different types of surgeries have been described. Functional results, after conservative treatment or arthrodesis, often find a decreased strength and range of motion. The sacrifice of the distal radioulnar joint could be one of the causes. We report the case of a 26-year-old patient who presented with a Campanacci Grade III giant cell tumor of the distal radius. We managed his case by the association of en bloc resection and allograft reconstruction with the preservation of distal radioulnar joint. Hypothesis This procedure could improve functional results, without increasing the risk of recurrence at 2 years follow-up. Case Report The originality of our technique was the possibility of distal radioulnar joint conservation. We preserved a long portion of cortex bone all through the ulnar side of the distal radius. We then used an allograft of distal radius, fixed by a reconstruction anatomical plate. Results At 2 years follow-up, the range of motion was 100° with 60° of palmar flexion, 40° of extension, 75° of pronation, and 70° of supination. Radial and ulnar inclination were 10 and 15°, respectively. MTS (Musculoskeletal Tumor Society Score) 1993 was 88% and DASH score was 6. Concerning grip strength, it was measured at 85% in comparison with the other side. Pronation and supination strengths were 80 and 73%, respectively, in comparison with the other side. At follow-up, standard X-rays showed no recurrence. The allograft was well integrated. Conclusion Conservative treatment of the distal radioulnar joint allowed an almost ad integrum recovery, concerning strengths and range of motion. It allows a better functional recovery, without increasing the risk of recurrence.

Malignant Transformation of a Giant Cell Tumor of Bone Treated with Denosumab

2016 ◽  
Vol 6 (3) ◽  
pp. e78 ◽  
Author(s):  
Andrew Park ◽  
Cara A. Cipriano ◽  
Kirk Hill ◽  
Michael Kyriakos ◽  
Douglas J. McDonald
Keyword(s):  
Giant Cell Tumor ◽  
Giant Cell ◽  
Malignant Transformation ◽  
Cell Tumor
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